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Lacosamide as treatment of epileptic seizures - cost utility results for Sweden.

Bolin K, Berggren F, Forsgren L. Lacosamide as treatment of epileptic seizures - cost utility results for Sweden. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2009.01320.x. (c) 2010 The Authors Journal compilation (c) 2010 Blackwell Munksgaard. Objectives - To calculate cost per additional quality-adjusted life-year (QALY) for lacosamide as adjunctive treatment for patients with uncontrolled partia

CGRP blockers in migraine therapy: where do they act?

Calcitonin gene-related peptide (CGRP) is expressed throughout the CNS and peripheral nervous system, consistent with control of vasodilatation, nociception, motor function, secretion and olfaction. alphaCGRP is prominently localized in primary afferent C and Adelta fibres of spinal and trigeminal ganglia. Activation of the trigeminal nerve results in antidromic release of CGRP, acting through a C

Fogar i våtrum

Kostnaderna för att åtgärda fukt- och vattenskador i våra våtrum har ökat dramatiskt och oroväckande under senare år. I den skadeinventering som ingick i SABOs stora projekt 'Fukt och mögel i flerbostadshus' uppvisade 11,3 procent av våtrummen skador av olika slag

Customization of buildings using configuration systems - a study of conditions and opportunities in the Swedish timber house manufacturing industry

The aim of this project has been to study timber house manufacturers and provide guidance to those who aim to increase efficiency through the adaption of product modeling and eventually configuration. The findings in this report are based on a series of case studies within the abovementioned industry, which serves as a basis for the analysis and recommendations given. The Swedish timber house man

När tanken lyfter

This paper discusses the evolutionary function of certain advanced aspects of cognition, like planning, self-awareness, and free will. The inner environment of an agent consists of all representations which the agent can actively "think about". A distinction is made between immediate planning, where plans are made for present needs, and anticipatory planning, where future needs are predicted. Huma

Evidence for a rapid sea-level rise at 7600 years ago

Dating the transgression and subsequent regression in marginal basins of the southeastern Swedish Baltic Sea provides a new perspective of global ice-volume changes and the isostatic adjustment of the mantle after the retreat of the Scandinavian Ice Sheet from this area. Superimposed upon a smooth pattern of local sea-level rise, acceleration occurred ca. 7600 calibrated (cal) yr B.P., evidenced a