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The aggregation of the protein Amyloid-beta (Abeta) into plaques outside the nerve cells has been recognized in patients with Alzheimer’s disease since 1905. But eliminating the plaques has not helped patients so far. Still, Tomas Roos was recently recruited as a postdoc in our lab. He thinks that Abeta matters, but we may need to focus on the aggregates elsewhere. Earlier this spring, he defended

https://www.neuroinflammation.lu.se/article/does-alzheimers-disease-start-inside-neurons-interview-tomas-roos-recently-recruited-our-lab - 2026-06-07

Communication is key in research. Recently, our lab had a team-building day at the beach. And a simple Lego game can tell very much about the reasons behind the reproducibility crisis in science. Getting together to communicate new ideas and build relationships is critical for maintaining a vital research group. That is why our lab arranges a team-building once a year, together with the experiment

https://www.neuroinflammation.lu.se/article/why-research-replication-fails - 2026-06-07

Collaboration is the most efficient way of moving science forward. That is why our research group initiated a network inviting all researchers interested in physical activity investigations at Lund University. Since 2022, we coordinate CoPARLU, a new center of physical activity research at Lund University. Having a physically active lifestyle has been associated with a broad range of health benefi

https://www.neuroinflammation.lu.se/article/coparlu-centre-physical-activity-research-lund-university - 2026-06-07

Megg Garcia-Ryde’s thesis sheds light on the early pathological processes in Alzheimer’s disease and the interplay between neurons and microglia as the disease evolves. October 10, she defends her thesis. Now, she gives her perspectives from a close collaboration between the experimental neuroinflammation laboratory and the experimental dementia research group and how she brings together the exper

https://www.neuroinflammation.lu.se/article/neuroimmune-crosstalk-early-alzheimers-disease-phd-interview-megg-garcia-ryde - 2026-06-07

Nailing one's doctoral thesis by simply nailing it up for viewing is an old tradition that possibly dates back to Martin Luther. The tradition has lost its former glory but is still a reason to invite people to a party. Here, Megg Garcia Ryde talks about her nailing. How was the actual nailing? It took some time but went fairly smoothly! I’m the handy person in my household, so I brought my awl to

https://www.neuroinflammation.lu.se/article/nailed-it-why-do-swedes-nail-their-thesis - 2026-06-07

Microglia govern the brain and protect it, but in the wrong context, they can also cause harm. Their activity needs to be well timed and balanced, or things go off course. When they get stuck in the wrong gear, microglia can drive neurodegeneration. Scientists in the Neuroinflammation research group believe that by targeting a protein called Galectin-3, microglial states can be tuned. "We previous

https://www.neuroinflammation.lu.se/article/galectin-3-shapes-microglial-function-possible-target-alzheimers-disease - 2026-06-07

In a recent study from Lund University, researchers have discovered that metabolic changes in the blood cell, affect the development of blood during the fetal stage. They found a previously unknown metabolic regulator - a kind of switch - which turns out to be crucial for how different types of blood cells develop. In the long run, this could mean that natural killer cells, a type of white blood c

https://www.stemcellcenter.lu.se/article/increased-metabolism-mitochondria-resulted-higher-levels-natural-killer-cells - 2026-06-07

A multidisciplinary research team at Lund University has innovatively tackled what has long been a major problem in stem cell research. The project has now been awarded a Proof of Concept grant from the European Research Council, ERC. Jonas Larsson, Professor of Molecular Medicine, and his research colleague Ludwig Schmiderer, together with Martin Hjort, a researcher at NanoLund, have developed th

https://www.stemcellcenter.lu.se/article/how-nanostraws-can-increase-number-blood-stem-cells - 2026-06-07

Each year, Lund Stem Cell Center presents one of its members with its Article of the Year Award. This year three distinguished nominees contended for the title. Among them, Marie Jönsson, representing the research group Molecular Neurogenetics, was awarded Article of the Year 2021, for their work in revealing how the activation of ancient viruses during brain development causes inflammation. In th

https://www.stemcellcenter.lu.se/article/scc-article-year-award-goes - 2026-06-07

A team of researchers from Lund University and the Lund Stem Cell Center have developed a new memory-efficient tool for single-cell genomic analysis called Scarf. Now available in Nature Communications, this innovative, bioinformatics software has the potential to help researchers navigate a growing treasure trove of data and set them on the path to answering new scientific questions related to hu

https://www.stemcellcenter.lu.se/article/introducing-scarf-memory-efficient-solution-single-cell-genomic-analysis - 2026-06-07

Researchers at Lund University and Lund Stem Cell Center in Sweden have developed a new method for studying age-related brain disorders. The researchers have focused on the neurodegenerative disorder Huntington’s disease and the results have now been published in the journal Brain. Basic medical research often faces the challenge of developing disease models that correspond to specific disease mec

https://www.stemcellcenter.lu.se/article/researchers-reprogram-human-skin-cells-aged-neurons-study-neurodegenerative-disorders - 2026-06-07

Sofia Wijk will defend her Ph.D. thesis on the 8th of September 2022, with a vision to contribute to the development of future cell-based therapies for patients with chronic lung disease. She has dedicated the last several years to better understanding the regenerative properties and processes of stem cells in our airways. In this interview, she tells us about her research, her journey in academia

https://www.stemcellcenter.lu.se/article/phd-defence-interview-sofia-wijk - 2026-06-07

A large amount of lungs donated cannot be used for transplantation. Researchers at Lund Stem Cell Center, Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future. The researchers have launched a pilot study to investigate whether the treatment will have the same positive effects on human beings. About 19

https://www.stemcellcenter.lu.se/article/new-treatment-could-result-more-donor-lungs - 2026-06-07

Sarah Warsi will defend her Ph.D. thesis on the 4th of October 2022. Driven by the desire to improve patient outcomes, she has dedicated the last several years to studying both in the clinic and the lab. During that time, her research efforts have centered on a better understanding of the functionality and fate of blood stem cells to contribute to developing improved clinical therapies for patient

https://www.stemcellcenter.lu.se/article/phd-defence-interview-sarah-warsi - 2026-06-07

The Royal Swedish Academy of Sciences has elected two new members of the Academy’s class for medical sciences. One of them is Malin Parmar, Professor of Cellular Neuroscience at Lund University, and Principal Investigator at Lund Stem Cell Center. Together with her research group, Malin Parmar has conducted several groundbreaking studies on stem cells that have led to the development of new treatm

https://www.stemcellcenter.lu.se/article/malin-parmar-elected-royal-swedish-academy-sciences - 2026-06-07

On 14 October 2022, Jessica Giacomoni will defend her Ph.D. thesis. With the ultimate goal to develop a possible, future alternative to cell transplantation for the treatment of neurodegenerative disorders, her research efforts have focused on the direct conversion of human glial cells into therapeutic neurons directly within the brain. Here, she tells us about future possibilities with this emerg

https://www.stemcellcenter.lu.se/article/turning-glia-neurons-inside-brain-phd-interview-jessica-giacomoni - 2026-06-07

Ouyang Yuan defends her Ph.D. thesis on 14 October 2022. As a medical student with a longstanding interest in blood malignancies, her research has focused on better understanding the development of a specific type of blood cancer, acute myeloid leukemia (AML). The hope is that these findings will help lead to a better understanding of AML and future treatments that can one day prevent, delay, or c

https://www.stemcellcenter.lu.se/article/placing-acute-myeloid-leukemia-under-microscope-phd-interview-ouyang-yuan - 2026-06-07

Skåne University Hospital, Lund University and Leiden University Medical Center will collaborate to develop research, education and care delivery in the field of ATMPs (Advanced Therapy Medicinal Products). That is the essence of a Memorandum of Understanding that was signed at the SciLifeLab near Stockholm on Wednesday 12 October, during the state visit of the Dutch Royal couple in Sweden. During

https://www.stemcellcenter.lu.se/article/international-collaboration-strengthen-development-atmps - 2026-06-07

An investigational stem cell-based therapy for the treatment of Parkinson’s Disease, STEM-PD, has been given regulatory approval for a Phase I/IIa clinical trial. Ethical approval of the trial has already been obtained from the Swedish Ethics Review Authority, and the STEM-PD team, led from Lund University in Sweden, is thereby ready to proceed with the trial. “We are excited and looking forward t

https://www.stemcellcenter.lu.se/article/swedish-medical-products-agency-grants-approval-clinical-study-new-stem-cell-based-parkinsons - 2026-06-07

B cells and the antibodies they produce play an important role in our immune system, protecting us from the microscopic enemies that make us ill. Uncovering how they form and are ‘programmed’ during development is key to better understanding the immune response to infections and vaccinations. A new study by researchers from Lund Stem Cell Center at Lund University in Sweden provides new insights i

https://www.stemcellcenter.lu.se/article/how-b-cells-are-programmed-early-life-can-impact-long-term-immune-health - 2026-06-07