Severe asthma exerts a disproportionately heavy burden on patients and health care. Due to the heterogeneity of the severe asthma population, many patients need to be evaluated to understand the clinical features and outcomes of severe asthma in order to facilitate personalised and targeted care. The International Severe Asthma Registry (ISAR) is a multi-country registry project initiated to aid i

https://www.lupop.lu.se/article/international-severe-asthma-registry-isar-protocol-global-registry - 2025-08-29

In this article, several independent populations following exponential distribution with common location parameter and unknown and unequal scale parameters are considered. From these populations, several independent samples of generalized order statistics (gos) are drawn. Under the setup of gos, the problem of estimation of common location parameter is discussed and various estimators of common lo

https://www.lupop.lu.se/article/estimation-common-location-parameter-several-heterogeneous-exponential-populations-based-generalized - 2025-08-29

Information about how risk for bipolar disorder is transmitted across generations and how parental risk for bipolar disorder relates to their children's risk for schizophrenia and major depression is limited. Read more at https://pubmed.ncbi.nlm.nih.gov/32186664/

https://www.lupop.lu.se/article/extended-swedish-national-adoption-study-bipolar-disorder-illness-and-cross-generational-familial - 2025-08-29

Non-Alcoholic Fatty Liver Disease (NAFLD), a progressive liver disease that is closely associated with obesity, type 2 diabetes, hypertension and dyslipidaemia, represents an increasing global public health challenge. There is significant variability in the disease course: the majority exhibit only fat accumulation in the liver but a significant minority develop a necroinflammatory form of the dis

https://www.lupop.lu.se/article/european-nafld-registry-real-world-longitudinal-cohort-study-nonalcoholic-fatty-liver-disease - 2025-08-29

This paper measures consumption expenditures using registry data on income and asset holdings in Sweden. We show how a registry-based measure complements traditional survey measures of consumption and can alleviate some critical limitations. We describe the construction of our measure, which builds on prior work and exploits the identity coming from the household budget constraint between consumpt

https://www.lupop.lu.se/article/value-registry-data-consumption-analysis-application-health-shocks - 2025-08-29

Pelvic floor disorders (PFDs) are important public health concerns due to their increasing prevalence. Hence, there is an increasing need for developing systematically collected quality data to assist appropriate clinical decision‐making. This study aimed to develop a core data set for patients with PFDs based on the PFDs registry. Read more at https://onlinelibrary.wiley.com/doi/full/10.1111/luts

https://www.lupop.lu.se/article/development-core-data-set-pelvic-floor-disorder-patients-registry - 2025-08-29

Dementia was identified as a priority area for the development of a Clinical Quality Registry (CQR) in Australia in 2016. The Australian Dementia Network (ADNeT) Registry is being established as part of the ADNeT initiative, with the primary objective of collecting data to monitor and enhance the quality of care and patient outcomes for people diagnosed with either dementia or Mild Cognitive Impai

https://www.lupop.lu.se/article/protocol-clinical-quality-registry-dementia-and-mild-cognitive-impairment-mci-australian-dementia - 2025-08-29

Independent disease registries for pre-and post-approval of novel treatments for rare diseases are increasingly important for healthcare professionals, patients, regulators and the pharmaceutical industry. Current registries for rare diseases to evaluate orphan drugs are mainly set up and owned by the pharmaceutical industry which leads to unacceptable conflicts of interest. To ensure independence

https://www.lupop.lu.se/article/registries-orphan-drugs-generating-evidence-or-marketing-tools - 2025-08-29

Ragnar Söderbergs stiftelse finansierar projekt vid Stockholms och Lunds Universitet En framgångsrik digitalisering resulterar i ett unikt dataset som kastar nytt ljus på svensk industrihistoria. Planen är att göra datasetet offentligt, och bedömningen är att det kan bli internationellt uppmärksammat och användas i historiska studier av industrialisering.Läs mer här.

https://www.lupop.lu.se/article/projekt-att-digitalisera-svensk-industridata-beviljas-13-miljoner-kronor - 2025-08-29

Recruitment for Alzheimer's disease (AD)-focused studies, particularly prevention studies, is challenging due to the public's lack of awareness about study opportunities coupled with studies' inclusion and exclusion criteria, resulting in a high screen fail rate. Read more at https://pubmed.ncbi.nlm.nih.gov/32920626/

https://www.lupop.lu.se/article/alzheimers-prevention-registry-large-internet-based-participant-recruitment-registry-accelerate - 2025-08-29

Hypertension (HTN) has become a major public health problem which can cause serious complications when it is not well-controlled. Prevention and effective care of HTN require a population-based registry. Thus, establishing this registry can be used to collect comprehensive, timely, and reliable data on epidemiology cases. The aim is to create a registry for the collection of highly required prospe

https://www.lupop.lu.se/article/improving-hypertension-surveillance-data-management-prospective-data-requirements-implementation - 2025-08-29

The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital-based healthcare

https://www.lupop.lu.se/article/costs-diabetes-complications-hospital-based-care-and-absence-work-392200-people-type-2-diabetes-and - 2025-08-29

Non-Western immigrants to Europe are at high risk for type 2 diabetes. In this nationwide study including incident cases of type 2 diabetes, the aim was to compare all-cause mortality (ACM) and cause-specific mortality (CSM) rates in first- and second-generation immigrants with native Swedes. Read more at https://pubmed.ncbi.nlm.nih.gov/32979073/

https://www.lupop.lu.se/article/mortality-first-and-second-generation-immigrants-sweden-diagnosed-type-2-diabetes-10-year-nationwide - 2025-08-29

Several prediction models for falls/near falls in Parkinson’s disease (PD) have been proposed. However, longitudinal predictors of frequency of falls/near falls are poorly investigated. Therefore, we aimed to identify short- and long-term predictors of the number of falls/near falls in PD. Read more at https://link.springer.com/article/10.1007/s00415-020-10234-6

https://www.lupop.lu.se/article/longitudinal-prediction-falls-and-near-falls-frequencies-parkinsons-disease-prospective-cohort-study - 2025-08-29

The objective was to describe the epidemiology, bacteriology, clinical presentation, risk factors for endocarditis (IE), diagnostic workup, and outcome of patients with bacteremia caused by the non-influenzae Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella genera (HACEK). A retrospective population-based cohort of patients with bacteremia collected from 2012 to 2017 was iden

https://www.lupop.lu.se/article/epidemiology-bacteriology-and-clinical-characteristics-hacek-bacteremia-and-endocarditis-population - 2025-08-29

Higher socioeconomic status (SES) is associated with lower mortality, and this correlation has been confirmed using different indicators across several geographical settings. Nevertheless, the timing of the emergence of the SES gradient remains unclear. We used individual-level longitudinal data for a regional population in southern Sweden covering the period between 1813 and 2014, and we applied

https://www.lupop.lu.se/article/ses-inequalities-cause-specific-adult-mortality-study-long-term-trends-using-longitudinal-individual - 2025-08-29

Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fetma och hjärtsjukdomar   Föredrag av professor Olle Melander Professor Olle Melan

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2025-08-29

They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, professor at the University of Oxford, who is also now to be an honorary doctor at Lun

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2025-08-29

Four researchers have been awarded grants from The Bo and Kerstin Hjelt Diabetes Foundation. The grant consists of Euro 50 000 each and are aiming towards better treatments and prevention of type 2-diabetes. Improved life expectancy and quality of people with diabetesDiabetes affects millions of patients around the world. The two main types of the disease, type 1 and type 2, are both characterized

https://www.ludc.lu.se/article/200000-euro-diabetes-research - 2025-08-29

There has been no known link between diabetes and vitamin A -- until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.The researchers initially discovered that insulin-producing beta-cells contain a large quantity of a cell surface receptor for vitamin A. "There are no unnecessary surface receptors in human cells. They all serve a purpose but which, in ma

https://www.ludc.lu.se/article/role-vitamin-diabetes - 2025-08-29