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Dickson E, Soylu-Kucharz R , Petersén Å and Björkqvist M. Mol Metab. 2022 Mar;57:101439. doi: 10.1016/j.molmet.2022.101439. Epub 2022 Jan 7. Abstract Objective In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progress

https://www.huntington-research.lu.se/hypothalamic-expression-huntingtin-causes-distinct-metabolic-changes-huntingtons-disease-mice - 2026-08-03

Soylu-Kucharz R, Khoshnan A and Petersén Å. iScience 2022 Jan 19;25(2):103771. doi: 10.1016/j.isci.2022.103771. eCollection 2022 Feb 18. Abstract Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin (HTT) gene. Metabolic changes are associated with HD progression, but underlying mechanisms are not fully known. As the IKKβ/NF-κB pathway is an

https://www.huntington-research.lu.se/ikkb-signaling-mediates-metabolic-changes-hypothalamus-huntingtons-disease-mouse-model-0 - 2026-08-03

Dickson E, Sai Dwijesha A, Andersson N, Lundh S, Björkqvist M, Petersén Å and Soylu-Kucharz R. Frontiers in Neuroscience. 2022 Nov 3;16:1027269. doi: 10.3389/fnins.2022.1027269. PMID: 36408416; PMCID: PMC9671106. Abstract Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington’s disease (HD), a neurodegenerative diso

https://www.huntington-research.lu.se/microarray-profiling-hypothalamic-gene-expression-changes-huntingtons-disease-mouse-models - 2026-08-03

Petersén Å1 and Kirik D2.1Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund SE-221 84, Sweden.2Brain Repair and Imaging in Neural Systems (BRAINS) Unit, Department of Experimental Medical Science, Lund University, Lund SE-221 84, Sweden.Journal of Clinical Investigation 17:1-3 (2014)AbstractA common form of the hyperkinetic movement disor

https://www.huntington-research.lu.se/twisting-mice-move-dystonia-field-forward - 2026-08-03

Hellem MNN, Cheong RY, Tonetto S, Vinther-Jensen T, Hendel RK, Larsen IU, Nielsen TT, Hjermind LE, Vogel A, Budtz-Jørgensen E, Petersén Å and Nielsen JE. Parkinsonism and Related Disorders. 99: 23-29 (2022).  Abstract Objective: Huntington's disease (HD) is an inherited neurodegenerative disease with motor, cognitive and psychiatric symptoms. Non-motor symptoms like depression and altered social c

https://www.huntington-research.lu.se/decreased-csf-oxytocin-relates-measures-social-cognitive-impairment-huntingtons-disease-patients - 2026-08-03

Bergh S, Cheong R Y, Petersén Å and Gabery S. Front. Mol. Neurosci., 14 September 2022; Sec. Molecular Signalling and Pathways; doi.org/10.3389/fnmol.2022.984317   Abstract Neurodegenerative disorders (NDDs) such as Huntington’s disease (HD) and the spectrum of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are characterized by progressive loss of selectively vulnerable popu

https://www.huntington-research.lu.se/oxytocin-huntingtons-disease-and-spectrum-amyotrophic-lateral-sclerosis-frontotemporal-dementia - 2026-08-03

Furby H, Moore S, Nordstroem A-L, Houghton R, Lambrelli D, Graham S, Svenningsson P and Petersén Å. Journal of Neurology. 270(2): 864-876 (2023) doi:10.1007/s00415-022-11418-y. Abstract Background: Huntington's disease (HD) is a rare, neurodegenerative disease and its complex motor, cognitive and psychiatric symptoms exert a lifelong clinical burden on both patients and their families. Objective:

https://www.huntington-research.lu.se/comorbidities-and-clinical-outcomes-adult-and-juvenile-onset-huntingtons-disease-study-linked - 2026-08-03

7.5 CREDITS | SPRING TERM In this course, the student will learn to understand and review the structures of social theories. OverviewAbout the courseIn contrast to courses that teach theory only from the perspective of given scholars, themes, and content, this course aims to demystify theory-driven research by making the practical knowledge of meta-theory explicit. The student will thereby acquire

https://graduateschool.sam.lu.se/course-catalogue/profile-and-elective-courses/spring-term-courses/structure-social-theory-simp58 - 2026-08-03

OverviewIn the Autumn term, Graduate School offers the following methods courses:SIMM52: Designing Research in Social SciencesThis course aims to provide the student with an understanding of and skills in research design in the social sciences. (7,5 credits)SIMM53: Methods in Contemporary Middle Eastern StudiesThis course in Methods in Contemporary Middle Eastern Studies is designed to introduce s

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods - 2026-08-03

OverviewIn the Spring term, Graduate School offers the following courses in methods and theory of science:SIMM23: Theory of Science for the Social SciencesThe aim of the course is to provide comprehensive understanding of contemporary Theory of Social Science. Hence the core of the course is presentations and critical discussions of major theories of Social Science as they revolve around epistemol

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/spring-term-courses-methods-and-theory-science - 2026-08-03

Lena Karlsson Director of Studies, Graduate School Email: lena [dot] karlsson [at] genus [dot] lu [dot] se Lena's profile on the LU Research Portal Catia Gregoratti Programme Director, MSc in Global Studies Email: catia [dot] gregoratti [at] svet [dot] lu [dot] se Catia's profile on the LU Research Portal Anne Jerneck Programme Director, MSc in Development Studies Email: anne [dot] jerneck [at] lu

https://graduateschool.sam.lu.se/contact/our-directors - 2026-08-03

15 CREDITS | SPRING TERM This course focuses on significant feminist interventions to social theories within the distinct but interrelated spheres of the economic, political, social and sexual. As a student of this course, you will be trained in the diversity of the field of feminist theory, including its debates, theoretical contributions and analytical tools. Overview About the course Students w

https://graduateschool.sam.lu.se/course-catalogue/profile-and-elective-courses/spring-term-courses/critical-feminist-perspectives-social-theory-simp28 - 2026-08-03

PROFILE AND ELECTIVE COURSES OverviewSIMP02 - Globalisation, Conflict, Security and the StateThe objectives of this course are to provide students with different theoretical perspectives to critically analyse (a) the continuing relevance of the state and (b) positive and negative consequences of globalisation processes for various dimensions of security, such as military, political, economic, cult

https://graduateschool.sam.lu.se/course-catalogue/profile-and-elective-courses/spring-term-courses - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course aims to provide the student with an understanding of and skills in research design in the social sciences. Overview Course content The course aims to provide the student with an understanding of and skills in research design in the social sciences. More specifically, the following issues are covered by the course: research approaches,  applied philosophy of sc

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/designing-research-social-sciences-simm52 - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course in Methods in Contemporary Middle Eastern Studies is designed to introduce students to the methodological debates and methods engaged in Middle Eastern Studies. Overview Course content This course aims to provide students with a broad-based training in research methodologies which enables them to use a range of research instruments and analyse different types

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/methods-contemporary-middle-eastern-studies-simm53 - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course aims to provide students with an understanding of key issues in feminist methodologies and theories of knowledge. OverviewCourse contentThe following issues are covered by the course: an overview of key concepts in theory of science in feminism,issues and debates in feminist theories of knowledge,main methodological approaches and traditions in feminist resear

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/feminist-methodologies-and-theories-knowledge-simm54 - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course aims to introduce students to approaches and methods in applied global studies research. Overview Course content It provides students with knowledge to be able to identify diverse theoretical underpinnings and methodological tools used to generate and analyse data in the context of a multidisciplinary and evolving field of studies. Emphasis will be placed on q

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/research-global-studies-simm57 - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course provides ample learning opportunities for the student to access, compare and understand a variety of research approaches and methods in contemporary development studies. Overview Course content With an emphasis on qualitative research, the course will demonstrate and highlight main approaches and principles for the collection, construction and analysis of diff

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/methods-development-studies-simm58 - 2026-08-03

7.5 CREDITS | AUTUMN TERM This course surveys the main genres of document-based research, such as secondary data research and archival research, and provides some depth regarding selected types of such research. OverviewPlease note that this course is also offered in the spring term. Course contentThe course surveys mostly qualitative approaches, including thematic analysis, (qualitative) content

https://graduateschool.sam.lu.se/course-catalogue/courses-methods-and-theory-science/autumn-term-courses-methods/document-research-simm59 - 2026-08-03

15 CREDITS | SPRING TERM Globalisation is a contested notion, which relates to the debates on changes and continuities in international relations. The objectives of this course are to provide you with different theoretical perspectives to critically analyse (a) the continuing relevance of the state and (b) positive and negative consequences of globalisation processes for various dimensions of secu

https://graduateschool.sam.lu.se/course-catalogue/profile-and-elective-courses/spring-term-courses/globalisation-conflict-security-and-state-simp02 - 2026-08-03