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Abstract – Background: Cytologic examination of lymph nodes and serous effusions is of value in the diagnosis of small cell lymphomas. The World Health Organisation (WHO) has recently published a reporting system relating to the cytologic examination of lymph nodes, spleen, and thymus to standardise the approach to reporting such specimens. Summary: An overview of the WHO reporting system is given
Enhancing the transformation-induced plasticity effect in steel-based binders through deformation-induced martensitic transformation requires careful control of the austenite stability. This study investigated the effect of binder fraction on the thermal stability of austenite in the WC-(Fe,Ni) system with different binder contents within the WC + binder + graphite equilibrium region. Binder marte
Conventional or ‘true’ memory CD8+ T cells (TTM) arise from immunologically naive T cells that circulate in the periphery after selection in the thymus. During infection or immunization by a foreign antigen, naive T cells can receive antigen-specific activation signals after recognition of MHC-antigenic peptide complexes. But the CD8+ T-cell population in immunologically naive hosts is not restric
The number of people seeking help for mental illness is increasing across all ages, creating a major burden for individuals, families, and the society. While personalized medicine is advancing in other fields, diagnosis and treatment of mental disorders remain largely symptom-based and fail to capture individual, sex, and gender differences in risk, manifestation, and treatment response. Early sig
Effective control over the alignment of 2D nanomaterials in solution is critical for optimizing their macroscopic properties. However, the fundamental factors governing this alignment remain poorly understood. This study addresses this gap by investigating the disorder-to-order transition states of Ti3C2Tx MXene sheets. We specifically examine the interplay among sheet sizes, concentrations, and s
Background Obstructive sleep apnea (OSA) is associated with autonomic dysfunction and increased cardiovascular risk, but the effects of continuous positive airway pressure (CPAP) on exercise-derived autonomic responses in patients with coronary artery disease (CAD) remain unclear. Methods This study included nonsleepy patients (Epworth Sleepiness Scale score <10) with CAD and OSA (apnea–hypopnea i
Metal joining remains an essential yet challenging process in manufacturing, particularly for components with small dimensions, multiplex, delicate geometries, or dissimilar metals, where conventional joining methods can be insufficient. Here, we introduce Gas Actuated Bonding (GAB), a novel joining method that employs gaseous melting-point-depressant (MPD) agents to induce a diffusion-active stat
Amelogenin self-assembly is a critical step in enamel matrix organization, supporting the spatial confinement of transient ACP and orchestrating hydroxyapatite nucleation and ordered growth. Studies have demonstrated that amelogenin self-assembles into nanoribbons by forming an amyloid-like structure that matches the cross-β pattern observed in the developing enamel matrix. However, molecular dete
PURPOSE: RAD51, a central player in the response to DNA damage, has been suspected to contribute to tumour resistance to therapy. A single-nucleotide polymorphism, RAD51 135G>C, in the untranslated region of the RAD51 gene elevates breast cancer risk among BRCA2 carriers. In this study, it was investigated whether this polymorphism is related to prognosis of breast cancer and RAD51 protein express
Microplastics and nanoplastics (MNPs) are ubiquitous environmental pollutants with increasing implications for human health. While their presence in human tissues is established, the molecular mechanisms driving their potential neurotoxicity remain unclear. This study investigates the impact of polystyrene (PS) on amyloid protein misfolding and cellular metabolism using optical photothermal infrar
X-ray absorption spectroscopy (XAS) measurements were performed at the oxygen K-edge using aqueous solutions of succinic and maleic acids. Molecular dynamics simulations were employed to perform structural sampling and calculate the theoretical spectra using the framework of the density functional theory. When the pH was varied, the first peak in the XAS profiles exhibited different behaviors for
3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua and 2I/Borisov. Its unusually high excess velocity and active cometary nature make it a key probe of the Galactic population of icy planetesimals. Understanding its origin requires its past trajectory through the Galaxy to be traced and the possible role of stellar encounters to be assessed, both as a potential or
Context. A growing number of white dwarfs (WDs) exhibit one or more signs of remnant planetary systems, including transits, infrared excesses, and atmospheric metal pollution. WD 1054-226 stands out for its unique, highly structured, and persistent photometric variability.Aims. We investigate the long-term stability and nature of the periodic signals observed in WD 1054-226 to better understand th
