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Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies and is known for its high resistance and low response to treatment. Tumor immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Karyopherin alpha 2 (KPNA2), a member of the nuclear transporter family, is elevated in multiple human cancers and accelerates carcinogenesis. Howeve
Healthcare in Sweden is dealing with problems regarding accessibility for patients. Moreover, there is a lack of an overall model concerning matching specialist care to patients. Against this background, the purpose was to develop a preliminary healthcare matching model and discuss the barriers of this model. Theoretically, the study draws on the concepts of matching and coordination completed wit
Systembolaget kan genom sin monopolställning låta storsäljarna finansiera det udda utbudet, det lokala utbudet, personalens kompetens och ett stort samhällsansvar. Denna affärsmodell skulle med fördel till exempel kunna föras över till detaljhandel med fisk och skaldjur.
The aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi’s What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomobThe aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi's What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomob
Lack of tools for detailed, real-time observation of mosquito behavior with high spatio-temporal resolution limits progress towards improved malaria vector control. We deployed a high-resolution entomological lidar to monitor a half-kilometer static transect positioned over rice fields outside a Tanzanian village. A quarter of a million in situ insect observations were classified, and several inse
Background COVID-19 is a rapidly spreading disease that has caused extensive burden to individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently needed. This is the second edition of a living systematic review of randomized clinical trials assessing the effects of all treatment interventions for participants in all age groups with COVID-19. Methods and findings
This collaborative statement from the International Society for Holter and Noninvasive Electrocardiology/ Heart Rhythm Society/ European Heart Rhythm Association/ Asia Pacific Heart Rhythm Society describes the current status of mobile health ("mHealth") technologies in arrhythmia management. The range of digital medical tools and heart rhythm disorders that they may be applied to and clinical dec
