Filtyp
Background Although the role of smoking as a risk factor for emphysema in α1-antitrypsin deficiency (AATD) is well known, never-smokers with severe AATD may also develop lung disease, ranging from mild asymptomatic disease to severe emphysema. Methods We performed a cross-sectional and observational study to analyse the characteristics of the population of never-smoker severe AATD (genotype) indiv
Background: Despite recommendations by EU, surveillance of Lyme neuroborreliosis (LNB) is still not fully implemented in all member states, Sweden being one of them. Laboratory-based notifications on positive Borrelia antibody index (AI) in paired cerebrospinal fluid-serum samples alone have been suggested for surveillance of LNB. Objectives: We aim to describe the epidemiology of Lyme borreliosis
Background: Transcatheter aortic valve replacement (TAVR) is increasingly used in patients with bicuspid aortic valve (BAV) stenosis, but there is limited comparative data on balloon-expandable (BEV) versus self-expanding valves (SEV) in this population. Aim: To compare clinical and hemodynamic outcomes between BEVs and SEVs in patients with BAV stenosis. Methods: This observational cohort include
Stiffening of tissue is a hallmark of cancer progression, promoting invasive phenotypes through altered cell-extracellular matrix (ECM) interactions. However, how fully formed epithelial structures respond to mechanical cues within their native ECM environment remains poorly understood. Here, using a 3D in situ stiffening hydrogel system that enables modulation of stiffness around mature normal ma
Background: People with intellectual disabilities experience significant health inequities. Digital interventions for health promotion are rarely designed from their specific needs. This study aimed to uncover core qualities of digital interventions for health promotion by exploring factors influencing health behaviours amongst people with intellectual disabilities. Methods: This study was conduct
Purpose – Our research examines the impact of Islamic religiosity, exploring the role of religious actors, religious ideas (knowledge-based religiosity) and religious practice, on the involvement in early-stage entrepreneurial activity at the provincial level in Indonesia. Design/methodology/approach – We rely on the survey conducted by Global Entrepreneurship Monitoring in Indonesia, spanning fro
This study presents a detailed simulation-based analysis of the detection limits of multi-element monolithic Germanium (Ge) detectors to cadmium traces in environmental soil samples. Using the capabilities of the Geant4 Monte Carlo toolkit in combination with the Solid State Detector Package, we evaluated the detection limit variation with the sample-to-detector distances and photon flux. These si
INTRODUCTION: The rapid digitalisation of workplaces presents both challenges and opportunities for older workers. This scoping review examines how digital technologies impact social support for older workers, focusing on emotional, informational, and instrumental support within professional environments. While social support is critical for well-being and productivity in ageing workforces, the ef
Objectives: This study aimed to assess the relationship between dietary intake and disease outcomes in patients with radiographic axial spondyloarthritis (r-axSpA), focusing on inflammation and disease activity, while also evaluating other health outcomes, and to compare dietary intake between patients and controls. Method: In a cross-sectional analysis, we studied 295 patients with r-axSpA (modif
Background: The recommended treatment for hyposmia (a clinically reduced sense of smell) is olfactory training using odor containers that the patients smell twice a day for several weeks. Adherence to the olfactory training regimen is, however, generally low. We aimed to investigate if a new form of odor delivery, using scented nasal inserts, could enhance adherence to olfactory training by allowi
Background: Studies in breast cancer patients have consistently shown that physical activity improves survival. We examined if change in physical activity from before to after a breast cancer diagnosis is associated with outpatient specialist care use and hospitalisations in women with type 2 diabetes mellitus (T2DM). Methods: This register-based cohort study included 2145 women with T2DM who self
Sammanfattning Det är enbart arbetstagare som omfattas av det arbetsrättsliga skyddet i lagstiftningen. Därmed utgör arbetstagarbegreppet en viktig del av arbetsrätten. Definitionen av begreppet får en allt större betydelse då sättet att organisera arbetet förändras kontinuerligt i och med att nya anställningsformer tillkommer. Uppsatsen undersöker hur EU och Sverige definierar och tillämpar arbAbstract The Labour law protection only covers those who are considered employees. Thus, the concept of employee is a significant part of the Labour law. The definition is becoming increasingly important as the way of organizing the work is continuously changing as new forms of employment are added. The essay examines how the EU and Sweden define and apply the concept of employee and what similar
Despite the need for bold rapid action when it comes to the climate emergency, the transition to a sustainable society is slower than desired, and disagreements on what actually matters within environmental action stunt progress. In an ever more complex society, where every day – seemingly innocent - acts such as lighting a tea-light has a negative environmental impact, it is increasingly difficul
The purpose of this study is to examine the significance of the office environment for organizations’ attractiveness as employers, as well as how the office environment may influence both efficiency and employee satisfaction in the workplace. The study particularly focuses on workplaces characterized by innovative, aesthetic, and experience-based office solutions. By analyzing the relationship bet
Den demografisk utveckling i flera länder medverkar till att allt fler kommer att behöva arbeta tillen högre ålder i framtiden. Det kommer alltså att fler äldre i arbetslivet i framtiden. Arbetslivet ärunder ständig utveckling och förändring. En del äldre arbetsmiljöproblem har försvunnit, andrakvarstår, samtidigt som ny ständigt uppstår. Hur och vad som påverkar arbetstagare i olika åldrarbehöver
OBJECTIVE: To evaluate short-term outcomes and identify predictors of morbidity and mortality following multivisceral oncologic resections involving the pancreas.SUMMARY BACKGROUND DATA: Multivisceral resections including the pancreas are required for locally advanced abdominal malignancies but are associated with considerable perioperative risk. While smaller series suggest acceptable outcomes in
BACKGROUNDAmyloid beta (Aβ) antibodies are the only therapies to slow cognitive decline in Alzheimer's disease (AD). Yet the sites where antibodies engage Aβ in the brain and mechanisms that lower Aβ are not fully understood. Defining Aβ antibody localizations in the brain is essential to understand how immunotherapy is beneficial for AD.METHODSN-terminal Aβ antibody 6E10 was injected via three di
This study presents the first direct measurement of aluminum monohydride (AlH) distribution and dynamics during aluminum combustion. Single micron-sized aluminum droplets were burned in a controlled H₂O/N₂/O₂ environment to ensure repeatable conditions. A dual-wavelength laser absorption imaging system is used to quantify the AlH concentration with high temporal and spatial resolution. The results
