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Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

Sleep disturbances are prevalent among elderly populations and are linked to various health complications. Understanding the underlying biological mechanisms contributing to sleep disorders is crucial for developing targeted interventions. In this study, we measured 355 plasma proteins in an elderly Japanese cohort (n=77) using a high-throughput proteomic platform. Additionally, we collected over

We developed an algorithm for the early screening of autism spectrum disorder using baby cry sound. We collected the sound using a smartphone application to record it in their daily life. We employed the Japanese version of the Modified Checklist for Autism in Toddlers (M-CHAT) for the evaluation of the autism spectrum. We built a prediction model for binary classification using least absolute shr

Background and AimsAdolescent mental health has declined in recent decades. Few studies have explored whether shifts in interpersonal behaviours– both in-person and online– can help explain this decline. Using data from two Swedish cohorts (2007–2008, 2023–2024), we examined (1) 15-year time trends (2007–2008 vs. 2023–2024) in interpersonal behaviours (victimization, aggression, prosocial behaviou

Background: Patients with relapsing remitting multiple sclerosis (RRMS) treated with the high-efficacy drugs natalizumab (NTZ) or rituximab (RTX) generally show no evidence of disease activity. Currently, there is no head-to-head comparison between NTZ and RTX of neurodegenerative and neuroinflammatory biomarkers in cerebrospinal fluid (CSF). Objectives: To compare CSF biomarkers in a stable RRMS

Aerosols from volcanic eruptions impact our climate by influencing the Earth's radiative balance. The degree of their climate impact is determined by the location and injection altitude of the volcanic SO2. To investigate the importance of utilizing correct injection altitudes, we ran climate simulations of the June 2009 Sarychev eruptions with three SO2 datasets in the Community Earth System Mode

Tullkomplexet is an artist-driven collective formed by Felice Hapetzeder, Marit Lindberg, and Johan Suneson, who explore the city through artistic methods, site-related installations, and participatory processes. In the project Tullkomplexet/Greenroom/Sorgenfri, presented at Molekyl Gallery in Malmö in autumn 2024, the Sorgenfri neighborhood was activated as a site through a total environment, wheTullkomplexet is an artist-driven collective formed by Felice Hapetzeder, Marit Lindberg, and Johan Suneson, who explore the city through artistic methods, site-related installations, and participatory processes. In the project Tullkomplexet/Greenroom/Sorgenfri, presented at Molekyl Gallery in Malmö in autumn 2024, the Sorgenfri neighborhood was activated as a site through a total environment, whe

Heart failure is a common condition with a high burden of morbidity and mortality globally. Despite modern advancements in diagnostic evaluation and therapeutic strategies, challenges remain in providing optimal treatment for the individual patient. Heart-failure phenotyping requires imaging modalities for assessment of structures and function. This thesis is based on four studies which apply nove

For decades, social scientists and activists have advocated for equal participation of citizens in decision-making about development and equitable futures. The urgency of this call has intensified with the climate emergency, pushing communities towards resilience. Yet, the concept of participation remains contested. This systematic review examines 187 articles to understand how participatory proce

Musikalbum av Thomas Ringdahl i genren folkmusik/visa, utgiven på Vidar Records 2024, inspelad 2022. Mats Edén spelar fiol på på 9 av 12 spår.

Med utgångspunkt i repertoar med rötter i folkmusik från Iberiska halvön fortsätter Groupa sitt arbete med att skapa helt nya musikaliska uttryck baserade på traditionsmusik. Detta är det fjärde albumet i serien Kind of Folk, här i samarbete med spanska och portugisiska musiker. Medverkar gör slagverksduon Ttukunak Txalaparta, bestående av Maika Gomez och Sara Gomez, sångerskan och slagverkaren Va

Musiken är ett resultat av ett undersökande improvisationsprojekt tillsammans med professor Stefan Östersjö uifrån de förutsättningar som ges i mötet mellan vind, vatten, eolisk gitarr och mina stråkinstrument. Inspelningen skedde vid sjön Vomb. Det är en vidareutveckling av ett tidigare samarbete mellan paleoekolog Anna Broström och geolog Kalle Ljung där Edén utifrån deras forskning kring sjön V

Till grund för den här boken ligger föreläsningar som utvecklats efterhand på kurser i svensk grammatik för blivande eller redan verksamma lärare i svenska som andraspråk och på kurser för utländska studenter. Boken vill förmedla kunskaper om några centrala områden av den svenska andraspråksgrammatiken. Den vill också presentera, utveckla och tillämpa de perspektiv på grammatiken och ordförrådet s

Abstract in DanishLars-Johan Ekerots bog om svensk som andetsprog foreligger nu i dansk oversættelse og med et noteapparat henvendt til dansksprogede læsere.Bogen har siden udgivelsen i 1995 været et standardværk på læreruddannelser og andre uddannelser i svensk i Sverige og Finland samt på kurser i svensk som fremmedsprog.Bogen har også længe været flittigt brugt af studerende og kommende undervi

Regeneration of Norway spruce, Picea abies, forests is to a large extent depending on the production of seeds from high quality plus trees in orchards. However, the seed yield is variable and unpredictable due to weather, pest insects and diseases. Thus, more knowledge is needed to improve planning of harvest and mitigation of pests and diseases to secure future forest regeneration. In this study,

While digital play installations for outdoor use are becoming more common, little work has been done on how such technology shapes play in nature-rich environments. We performed a study of children's self-directed play with access to nature as well as digital installations. Our findings show that play with nature materials and digital installations emerged in different ways. Most notably, imaginat

PURPOSE: To contribute to an in-depth understanding of how the concepts accessibility, usability, and universal design interact and can be harmonised to create conditions for participation in the 21st century.MATERIAL AND METHODS: Ideas, empirical research, and selected literature from health science, engineering, and design constituted the material for a scientifically grounded analysis.RESULTS: