Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation : a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST)
Background: The optimal timing of oral anticoagulation for prevention of early ischaemic stroke recurrence in people with acute ischaemic stroke and atrial fibrillation remains uncertain. We aimed to estimate the effects of starting a direct oral anticoagulant (DOAC) early (≤4 days) versus later (≥5 days) after onset of ischaemic stroke. Methods: For this systematic review and meta-analysis we sea
