BACKGROUND: A chronic disease impacts a patient's daily life, with the burden of symptoms and managing the condition, and concerns of progression and disease complications. Such aspects are captured by Patient-Reported Outcomes Measures (PROM), assessments of e.g. wellbeing. Patient-Reported Experience Measures (PREM) assess patients' experiences of healthcare and address patient preferences. Biom

Nasopharyngeal cancer (NPC) is associated with the Epstein-Barr virus (EBV). The clinical presentation and prognosis of NPC is well described, but not in relation to intralesional EBV-DNA load. In a retrospective design, 48 patients with NPC were examined. Patient history was re-evaluated, and diagnostic biopsies were re-examined. Furthermore, intralesional EBV-DNA was quantitated and HPV status d

The aim of this work was to develop a method for assessing the drying performance of a hygienic, small-scale fruit juice preservation process called Solar Assisted Pervaporation (SAP). SAP is a batch process that allows for fruit juices or purées to be solar dried in water vapour-permeable membrane pouches in rural and remote areas. Traditional methods for measuring water vapour flux through membr

Osteopontin (OPN) plays a role in inflammation via recruitment of neutrophils and tissue remodeling. In this study, we investigated the distribution of OPN-expressing cells in the airway epithelium of normal lung tissue and that from patients with chronic obstructive pulmonary disease (COPD). OPN was detected on the epithelial cell surface of small airways and in scattered cells within the epithel

Aerosol composition and optical scattering from particles in the lowermost stratosphere (LMS) have been studied by comparing in-situ aerosol samples from the IAGOS-CARIBIC passenger aircraft with vertical profiles of aerosol backscattering obtained from the CALIOP lidar aboard the CALIPSO satellite. Concentrations of the dominating fractions of the stratospheric aerosol, being sulphur and carbon,

The idea that original soft tissue structures and the native structural proteins comprising them can persist across geological time is controversial, in part because rigorous and testable mechanisms that can occur under natural conditions, resulting in such preservation, have not been well defined. Here, we evaluate two non-enzymatic structural protein crosslinking mechanisms, Fenton chemistry and

Some of the most pressing concerns of our time, such as crises connected to migration, the welfare state, international law and terrorism, are part of the Swedish upper secondary school subject Social Science. This means that Social Science teaching easily generates intense emotions, sparks of which are lit in the encounter between the students, the teacher, and the specific content of the school

Inference of CO2 surface fluxes using atmospheric CO2 observations in atmospheric inversions depends critically on accurate representation of atmospheric transport. Here we characterize regional-scale CO2 transport uncertainties due to uncertainties in meteorological fields using a mesoscale atmospheric model and an ensemble of simulations with flow-dependent transport errors. During a 1-month sum

This study systematically examines the regional uncertainties and biases in carbon dioxide (CO2) mole fractions from two of the state-of-the-art global CO2 analysis products, namely, the Copernicus Atmosphere Monitoring Service (CAMS) real-time atmospheric analysis from the European Centre for Medium-Range Weather Forecasts (ECMWF) and the CarbonTracker Near-Real-Time (CT-NRT) reanalysis from the

The significance and robustness of the link between Arctic sea ice loss and changes in midlatitude weather patterns is investigated through a series of model simulations from the Community Atmosphere Model, version 5.3, with systematically perturbed sea ice cover in the Arctic. Using a large ensemble of 10 sea ice scenarios and 550 simulations, it is found that prescribed Arctic sea ice anomalies

Using Arctic sea ice concentration derived from passive microwave satellite observations in autumn and early winter over the 1979-2014 period, the Arctic region was objectively classified into several smaller regions based on the interannual sea ice variability through self-organizing map analyses. The trend in regional sea ice extent (RSIE) in each region was removed using an adaptive, nonlinear,

A comprehensive dynamic control oriented model of a polymer electrolyte fuel cell (PEFC) is developed, considering the mixed effects of temperature, gas flow and capacitance. The fractional relationship between the dynamic output voltage and the capacitance, which escaped the attention in most previous studies is also addressed. Moreover, based on the developed PEFC model, a proportional integral

Protapion trifolii and P. fulvipes (Coleoptera: Brentidae) are major pests in European clover seed production. Previous studies have reported a high host plant fidelity of these weevils for red and white clover species, respectively, driven by host plant olfactory cues. Given the specific host preferences observed in these weevils, we aimed to elucidate to which extent such selectivity is reflecte

Central nervous system (CNS) involvement by cytospin is associated with increased risk of relapse in childhood acute lymphoblastic leukemia. We investigated if flow cytometric analysis of cerebrospinal fluid (CSF) at diagnosis improves the prediction of relapse. This prospective cohort study included patients (1.0–17.9 years) treated according to the Nordic Society of Pediatric Hematology and Onco

The data collected in this article is based on a performance test of a polymer electrolyte fuel cell (PEFC). The behavior the different parameters of a PEFC is analyzed considering different aspects relative to the inlet gases temperatures. The fuel cell was evaluated by means of a current sweep at different percentages of relative humidity between the feed gas and the cell. The relative humidity

I det fjärde numret av Essä uppmärksammas ett helt vanligt grässtrå – fårsvingeln – genom Olof Rudbeck den äldres avbildning av det i det stora botaniska verket Campus Elysii som under dramatiska omständigheter nästan brann upp i stadsbranden i Uppsala 1702. De som tittat på gräset och skrivit om det är Erik Bergqvist, Gunnar Eriksson, Honor C. Prentice, Birgitta Lillpers, Carin Franzén och Jakob