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Hydrodynamic interaction of a particle pair at Reynolds number 600

In the current study the focus is on the flow and particle interaction effects in the chaotic regime. The influence on the forces (i.e drag and lift), wake structures and flow patterns from different inflow boundary conditions and varying separation distances of a particle pair in tandem is discussed at a particle Reynolds number of 600.

IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis

Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (Pr3) are considered pathogenic in ANCA-associated necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. Modulation of ANCA IgG glycosylation may potentially reduce its pathogenicity by abolishing Fc receptor mediated activation of leukocytes and complement Here, we investigated

Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional data

PURPOSE. To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies. METHODS. Subjects with OAG were identified in nine surveys of randomly sampled populations using standard criteria for glaucomatous optic neuropathy. Subjects were of European, African, Chinese, and Hispanic ethnicity. The measure of OAG dama

Bridging the Gap: How do EU-Based Civil Society Organisations Acquire Their Internal Representation?

In recent decades, the emergence and development of pan-European civil society organisations have been prominent, including those representing interests of marginalised groups and raising related social issues. Typically composed of national and European level umbrella organisations, some of these organisations have grown as important interlocutors between EU institutions and civil society, and de

The prevalence of anemia and iron deficiency in IBD outpatients in Scandinavia

Objective. To evaluate the prevalence of anemia and iron deficiency (ID) among patients with inflammatory bowel disease (IBD) in the Scandinavian countries. Material and methods. A cross-sectional study including 429 IBD patients from six centers in Denmark, Norway and Sweden. Patients were screened for anemia and ID. Each center included similar to 5% of their IBD cohort. Patients were consecutiv

How accurate are continuum solvation models for drug-like molecules?

We have estimated the hydration free energy for 20 neutral drug-like molecules, as well as for three series of 6-11 inhibitors to avidin, factor Xa, and galectin-3 with four different continuum solvent approaches (the polarised continuum method the Langevin dipole method, the finite-difference solution of the Poisson equation, and the generalised Born method), and several variants of each, giving

Scaling of the mean and variance of population dynamics under fluctuating regimes

Theoretical ecologists have long sought to understand how the persistence of populations depends on the interactions between exogenous (biotic and abiotic) and endogenous (e.g., demographic and genetic) drivers of population dynamics. Recent work focuses on the autocorrelation structure of environmental perturbations and its effects on the persistence of populations. Accurate estimation of extinct

Oak leaves as aerosol collectors: relationships with wind velocity and particle size distribution. Experimental results and their implications

Advancing the understanding of the aerosol-capture efficiencies of forest components such as leaves and needles, and of the mechanisms that underpin these efficiencies, is essential to the many related issues of forest turnover of nutrients and pollutants. For idealized collectors (such as artificial plates or cylinders) aerosol-mechanics offers a means for calculating capture efficiencies. For li

An approach to constraint-based and mass-customizable product design

In traditional product development, several iterations are usually necessary to obtain a successful compromise between constraints emanating from engineering, manufacturing, and aesthetics. Moreover, this approach to product development is not well suited for true mass-customization, as the manufacturing company remains in control of all aspects of the shape of the product-to-be. In this article,

Investigation and optimisation of mobile Nal(Tl) and He-3-based neutron detectors for finding point sources

Neutron radiation produces high-energy gamma radiation through (n,gamma) reactions in matter. This can be used to detect neutron sources indirectly using gamma spectrometers. The sensitivity of a gamma spectrometer to neutrons can be amplified by surrounding it with polyvinyl chloride (PVC). The hydrogen in the PVC acts as a moderator and the chlorine emits prompt gammas when a neutron is captured

Images of the EU in EPA negotiations: Angel, demon - or just human?

A striking feature of the discourses surrounding the negotiations of Economic Partnership Agreements between the EU and developing states is the starkly contrasting pictures given of the role and nature of the EU. The Union is either portrayed as an angel, an actor with altruistic objectives, concerned primarily with the economic and social development of the ACP countries, or as a demon, an actor

Effects of Water Stress, Organic Amendment and Mycorrhizal Inoculation on Soil Microbial Community Structure and Activity During the Establishment of Two Heavy Metal-Tolerant Native Plant Species

Our aim was to examine the effect of water stress on plant growth and development of two native plant species (Tetraclinis articulata and Crithmum maritimum) and on microbial community composition and activity in the rhizosphere soil, following the addition of an organic amendment, namely sugar beet residue (SBR), and/or the inoculation with an arbuscular mycorrhizal (AM) fungus, namely Glomus mos

A TX VCO for WCDMA/EDGE in 90 nm RF CMOS

A VCO is implemented in an RF 90 nm CMOS process and covers the frequency range 2.55-4.08 GHz. Drawing 19 mA from 1.2 V, the phase noise at 20 MHz frequency offset from a 3.7 GHz carrier is -156 dBc/Hz, meeting the phase noise requirement for GSM/EDGE and SAW-less WCDMA transmitter after frequency division by 2 or by 4. A second version of the VCO covers an additional 4.90-5.75 GHz range, at the e

Diagnosis and progression of sacroiliitis in repeated sacroiliac joint computed tomography.

Objective. To assess the clinical utility of repeat sacroiliac joint computed tomography (CT) in sacroiliitis by assessing the proportion of patients changing from normal to pathologic at CT and to which degree there is progression of established sacroiliitis at repeat CT. Methods. In a retrospective analysis of 334 patients (median age 34 years) with symptoms suggestive of inflammatory back pain,