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Dynamic Standing Exercise in a Novel Assistive Device Compared with Standard Care for Children with Cerebral Palsy Who Are Non-Ambulant, with Regard to Quality of Life and Cost-Effectiveness
Children with cerebral palsy who are non-ambulant cannot stand or walk independently. In Sweden, daily static standing is part of standard care for these children even though it is time-consuming and costly, and while it may benefit the well-being of many children, it is inconvenient for others. A novel stander enables dynamic standing through walking movements. The aim of this study was to compar
Psychometric Properties of Clinical Indicators for Identification and Management of Advanced Parkinson’s Disease : Real-World Evidence From G7 Countries
Introduction: Standardized and validated criteria to define advanced Parkinson’s disease (PD) or identify patient eligibility for device-aided therapy are needed. This study assessed the psychometric properties of clinical indicators of advanced PD and eligibility for device-aided therapy in a large population. Methods: This retrospective analysis of the Adelphi Parkinson’s Disease Specific Progra
SPIRE—a software tool for bicontinuous phase recognition : application for plastid cubic membranes
Bicontinuous membranes in cell organelles epitomize nature’s ability to create complex functional nanostructures. Like their synthetic counterparts, these membranes are characterized by continuous membrane sheets draped onto topologically complex saddle-shaped surfaces with a periodic network-like structure. Their structure sizes, (around 50–500 nm), and fluid nature make transmission electron mic
Fibrinogen-like protein 2 in gastrointestinal stromal tumour
Gastrointestinal stromal tumour (GIST), the most common sarcoma of the gastrointestinal tract, can be treated effectively with tyrosine kinase inhibitors, such as imatinib. Cancer immune therapy has limited efficacy, and little is known about the immune suppressive factors in GISTs. Fibrinogen-like protein 2 (FGL2) is expressed either as a membrane-associated protein or as a secreted soluble prote
High versus low ultrafiltration rates during experimental peritoneal dialysis in rats : Acute effects on plasma volume and systemic haemodynamics
Introduction: Intradialytic hypotension is a common complication of haemodialysis, but uncommon in peritoneal dialysis (PD). This may be due to lower ultrafiltration rates in PD compared to haemodialysis, allowing for sufficient refilling of the blood plasma compartment from the interstitial volume, but the underlying mechanisms are unknown. Here we assessed plasma volume and hemodynamic alteratio
The role of work-integrated learning in preparing students for a corporate entrepreneurial career
Purpose: In the literature there is limited knowledge about how to prepare students for a corporate entrepreneurial career. The purpose is therefore to develop a framework for understanding the role corporate development projects play in corporate entrepreneurship education, and to examine the potential role of the design of the project. The study defines a corporate development project as a proje
Public Policy Formation in Morocco and the Role of Civil Society Dialogues
Frailty and osteoporosis in patients with hip fractures under the age of 60-a prospective cohort of 218 individuals
Research on younger patients with hip fractures is limited. This study adds knowledge on patient and injury characteristics, and DXA was investigated at the time of the fracture. Risk factors for osteoporosis and fractures were numerous among young patients, and osteoporosis was markedly more prevalent than in the general population.INTRODUCTION: Knowledge on younger patients with hip fractures is
Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes
Impaired beta cell function and beta cell death are key features of type 2 diabetes (T2D). Cocaine- and amphetamine-regulated transcript (CART) is necessary for normal islet function in mice. CART increases glucose-stimulated insulin secretion in vivo in mice and in vitro in human islets and CART protects beta cells against glucotoxicity-induced cell death in vitro in rats. Furthermore, beta cell
Impaired selective renal filtration captured by eGFRcysC/eGFRcrea ratio is associated with mortality in a population based cohort of older women
Deranged renal filtration of mid-sized (5-30 kDa) compared to smaller molecules (< 0.9 kDa) results in increased plasma levels of cystatin C (cysC) compared to creatinine resulting in a low eGFRcysC/eGFRcrea ratio. A ratio below 0.6 or 0.7, is termed shrunken pore syndrome (SPS), which in patient based studies is associated with mortality. Reference values for eGFRcysC/eGFRcrea ratio, the prevalen
Health systems strengthening to arrest the global disability burden : Empirical development of prioritised components for a global strategy for improving musculoskeletal health
Introduction Despite the profound burden of disease, a strategic global response to optimise musculoskeletal (MSK) health and guide national-level health systems strengthening priorities remains absent. Auspiced by the Global Alliance for Musculoskeletal Health (G-MUSC), we aimed to empirically derive requisite priorities and components of a strategic response to guide global and national-level ac
Lessons of History: An Impossible Equation? : Towards New Perspectives on Historical Learning
Lessons of history are two-sided cultural products. They serve as active instruments of temporal orientation in a society in which historical trajectories seem obsolete and the future open, but they are also passively framed within historical cultures that often have prefigured them. Thus, lessons are seldom arbitrarily constructed. while lessons of history for many centuries were highly esteemed
Strategies for old age and agency of the elderly in towns of the Low Countries in the Renaissance
Contrary to what is sometimes assumed, the elderly in the distant past could not always rely on voluntary care. Therefore, some of them had to develop strategies to secure assistance during old age. We focus on towns in the Low Countries, where family ties were weak, and ageing individuals likely had to plan for old age. We show how members of the middling layers of society could use wills and ret
Cardiovascular Dysautonomia in older adults. Aetiology, Diagnosis and Health related consequences
Cystatin C-based equations for estimating glomerular filtration rate do not require race or sex coefficients.
Estimation or measurement of glomerular filtration rate (GFR) is generally required for optimal treatment of patients. Plasma creatinine has been used for estimation of GFR since 1926 and plasma cystatin C since 1979. The creatinine level is strongly dependent upon muscle mass and as the average muscle mass of dif- ferent populations may vary, creatinine-based GFR-estimating equations have since 1
Använd ekvationer utan »ras«- termer för att bestämma GFR
Use cystatin C-based GFR-estimating equations Glomerular filtration rate (GFR) isestimated by creatinine or cystatin C-based GFR-estimating equations. Thosebased upon creatinine, but not those based upon cystatin C, use ”race” termsdue to that different populations differ in average muscular mass, influencing thecreatinine, but not the cystatin C, level. “Race” is not a biological, but a sociologiGlomerular filtration rate (GFR) is estimated by creatinine or cystatin C-based GFR-estimating equations. Those based upon creatinine, but not those based upon cystatin C, use ”race” terms due to that different populations differ in average muscular mass, influencing the creatinine, but not the cystatin C, level. “Race” is not a biological, but a sociological term, determined by self-assesment. Ne
The art of being governed : The implementation of Covid-19 policy in Swedish on-license alcohol service
The licensed serving of alcoholic beverages is an important institutional aspect of food culture. In Sweden, the Government’s policies to battle the Covid-19 pandemic meant further restrictions, including a temporary law, to mitigate contagion at licensed restaurants, bars, producers’ tasting events, etc. This paper inquiries into the “art” exercised by managers of such businesses, already used to
Post-Traumatic Growth during COVID-19 : The Role of Perceived Social Support, Personality, and Coping Strategies
Although many studies on mental health have been conducted among various populations during the COVID-19 pandemic, few studies have focused on post-traumatic growth (PTG) in the general population. The current study aimed to explore whether perceived social support, personality, and coping strategies are associated with PTG in the COVID-19 pandemic period. The study also investigated whether copin
Service users as supervisors in social work education: mending the gap of power relations
This chapter presents two projects in which service users are involved as supervisors of students in social work training at the University of Lund, Sweden, and the University of Agder, Norway. The chapter describes how both institutions relate to and try to solve dilemmas and problems connected to power, inequality and the creation of knowledge within the context of social work education.