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Multifocal electroretinography amplitudes increase after photocoagulation in areas with increased retinal thickness and hard exudates.

Abstract. Purpose: This study aimed to evaluate local response on multifocal electroretinography (mfERG) and to assess retinal thickness with optical coherence tomography (OCT) after focal laser treatment in areas with retinal oedema and exudates in patients with diabetic retinopathy. Methods: Twelve diabetes patients (aged 60 +/- 14 years, diabetes duration 16 +/- 8 years) treated with focal or g

Circadian variation in concentration of anti-Mullerian hormone in regularly menstruating females: relation to age, gonadotrophin and sex steroid levels.

BACKGROUND Anti-Müllerian hormone (AMH) is a promising marker of ovarian reserve. The aim of the study is to assess the circadian variation in AMH, and to evaluate its clinical relevance and biological aspects as an effect of age and other endocrine mechanisms involved in the regulation of AMH secretion. METHODS Nineteen healthy non-smoking, regularly menstruating female volunteers with body mass

Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults.

BACKGROUND: Autistic-like traits (ALTs), that is restrictions in intuitive social interaction, communication and flexibility of interests and behaviors, were studied in two population-based Swedish twin studies, one in children and one in adults: (1) to examine whether the variability in ALTs is a meaningful risk factor for concomitant attention deficit hyperactivity disorder (ADHD), anxiety, cond

Angular Momentum Population in the Fragmentation of Pb-208 at 1 GeV/Nucleon

A systematic study of the population probabilities of microsecond isomers produced following the fragmentation of 208Pb projectiles at 1 GeV/nucleon has been undertaken at the SIS/FRS facility at GSI Darmstadt. Gamma decays from approximately 20 isomeric states, mainly in the rare-earth and transitional nuclei with A∼180, were identified and the corresponding isomeric ratios deduced. The results a

Configuration Management Stories from the Distributed Software Development Trenches

Distributed projects are generally recognized as being more complex and adding a number of new challenges to project management. Configuration management (CM) can be considered the infrastructure of all types of project being they co-located or distributed and lack of CM or badly implemented CM will hurt any type of project. In this paper, we take a closer look at the role of CM in distributed pro

The Influence of Nitric Oxide on the Occurrence of Autoignition in the End Gas of Spark Ignition Engines

Full-cycle simulations of a spark ignition engine running on a primary reference fuel have been performed using a two-zone model. A detailed kinetic mechanism is taken into account in each of the zones, while the propagating flame front is calculated from a Wiebe function. The initial conditions for the unburned gas zone were calculated as a mixture of fresh gas and rest gas. The composition of th

Impact of Power Amplifier Nonlinearities in Multi-user Massive MIMO Downlink

In this paper, we investigate the impact of power amplifier (PA) nonlinear distortion in pre-coded multi-user large antenna or massive MIMO downlink systems. First, detailed signal and system models are derived for the received signal at single-antenna user equipment (UE) under channel-aware linear precoding in the base-station combined with behavioral models for the individual PA units, covering

Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH

Objective: Changes observed during adult GH deficiency (GHD) are most often reversed with the administration of recombinant human GH (rhGH). To avoid daily injections, a long-acting GH molecule has been obtained by covalent binding of polyethylene glycol (PEG) with rhGH (PEG-GH), allowing weekly s.c. injections. This study was designed to assess its efficacy and safety, in adult GHD subjects.Desig

The Emergence of Digitalization to the Manufacturing Sector in the Sustainability Context : A Multi-stakeholder Perspective Analysis

Sustainable digitalization in industry requires extensive preplanning to integrate business strategies with the concept of digitalized sustainability. However, stakeholders often have different perspectives, making alignment more challenging. Stakeholders in the digitalized sustainable manufacturing industry must be identified and prioritized for effective implementation. Therefore, the present st