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Annexin A1 (AnxA1) is a potent anti-inflammatory protein that downregulates proinflammatory cytokine release. This study evaluated the role of AnxA1 in the regulation of NLRP3 inflammasome activation and lipid release by starch-elicited murine peritoneal macrophages. C57bl/6 wild-type (WT) and AnxA1-null (AnxA1-/-) mice received an intraperitoneal injection of 1.5% starch solution for macrophage r

OBJECTIVE: To evaluate endocervical and vaginal environment changes in women using a levonorgestrel-releasing intrauterine system (LNG-IUS).METHODS: A quasi-experimental study included sixty women who had an LNG-IUS inserted in the Family Planning Clinic of UNICAMP between April and November of 2016. Women in reproductive age, non-pregnant, without the use of antibiotics and contraceptives seeking

INTRODUCTION: Genital hygiene can play an essential role in avoiding vulvovaginal discomfort and preventing infections. The scientific evidence on best practices on genital hygiene is scarce, and without doubt, gynecologists should be the best person to discuss and guide the subject.OBJECTIVE: Evaluate the general genital female gynecologist hygiene.METHODS: This descriptive analytic study identif

OBJECTIVE: To characterize the lipid profile in vaginal discharge of women with vulvovaginal candidiasis, cytolytic vaginosis, or no vaginal infection or dysbiosis.DESIGN: Cross-sectional study.SETTING: Genital Infections Ambulatory, Department of Tocogynecology, University of Campinas, Campinas, São Paulo-Brazil.SAMPLE: Twenty-four women were included in this study: eight with vulvovaginal candid

The aims of this study was to review the practical of the immediate vaginal diagnosis by Gram staining in the gynecological practice. The elucidation and characterization of the vaginal microorganisms is important for providing a better understanding of the women’s health and diseases, as well as the search for adequate diagnosis and treatment. Here we described the processes about the approaches

This paper examines the complementarity between the market for electric vehicles and fast charging on the Swedish market from the introduction of these technologies on the market until the third quarter 2015. Three ecosystems are identified based on the standards Chademo, CCS and the Tesla proprietary charging technology. The analysis points to the need for studying markets for electric vehicles a

Protoplanetary disks are the natural by-product of star formation and the sites of planet formation. Initially, they are composed of the gas and small solids they inherit from the molecular cloud they form in. The interactions between this material is complex and understanding their details is key for a complete picture of planet formation. The planet formation process begins with growth form abou

För att beskriva lagarna som styr den fysiska världen, behöver vi studera materiens struktur och hur dess olika delar växelverkar. Den grundläggande byggstenen för all känd materia i universum är atomen, vilken består av elektroner som rör sig runt en atomkärna. Atomen är ett kvantiserat mångkropparsystem, vars struktur karakteriseras av de diskreta och för ämnet unika energinivåer. Växelverkan meThis thesis deals with the relativistic modeling of atoms and ions. To interpret the stellar spectra and gain more insight from astrophysical observations, the underlying processes that generate the spectra need to be well understood and described. Examples of such processes are the interactions of atomic electrons with internal and external electromagnetic fields and with the nucleus.By exploring

The end-Permian mass extinction was the most severe biotic crisis in Earth’s history. In its direct aftermath, microbial communities were abundant on shallow-marine shelves around the Tethys. They colonized the space left vacant after the dramatic decline of skeletal metazoans. The presence of sponges and sponge microbial bioherms has largely gone unnoticed due to the sponges’ size and the cryptic

Spatially-distributed values of glacier aerodynamic roughness (z0) are vital for robust estimates of turbulent energy fluxes and ice and snow melt. Microtopographic data allow rapid estimates of z0 over discrete plot-scale areas, but are sensitive to data scale and resolution. Here, we use an extensive multi-scale dataset from Hintereisferner, Austria, to develop a correction factor to derive z0 v

Background: Research has indicated that interactive, computerized case simulations using immersive virtual reality (VR) technology may be beneficial in the augmentation of conventional methods of assessment and treatment in forensic psychiatry, primarily through providing an engaging and safe environment in which the user can practice and learn skills and behaviors. However, there does not appear

Fiji is a Small Island Developing State (SIDS) in the Pacific Ocean, with relatively population mobility. In this context, we study the individual-level characteristics of Fijian internal migration. Hence, our contribution lies in investigating migrant selectivity and differences in migratory behavior of different subgroups of the Fijian population. Specifically, we focus on factors such as gender

Purpose–This study aims to assess the associations of early marriage and spousal age difference(independent of early marriage) with reproductive and sexual health and autonomy in decision-making amongmarried women before conception.Design/methodology/approach–The present study was a part of a three-year community intervention toimprove the preconception health of young married women (20–35 years)

This article uses 1910 Japan–British Exhibition as a case study for examining the strategies employed by Japanese leaders to win Western acceptance for Japan as a ‘great power’ in the late nineteenth and early twentieth centuries. Like other contemporaneous imperial powers, Japanese leaders employed colonial imagery and discourses of otherness at large expositions to raise their status compared to

A key factor for the insulin response to oral glucose is the pro-glucagon derived incretin hormone glucagon-like peptide-1 (GLP-1), together with the companion incretin hormone, glucose-dependent insulinotropic polypeptide (GIP). Studies in GIP and GLP-1 receptor knockout (KO) mice have been undertaken in several studies to examine this role of the incretin hormones. In the present study, we revie

In 1876, the Kaitakushi, the Japanese government agency responsible for the settlement of the northern island of Hokkaido, hired three Americans from Massachusetts Agricultural College: William Smith Clark, William Wheeler and David Pearce Penhallow. Their task was to establish a comparable institution in Hokkaido, Sapporo Agricultural College, that would spread American-style scientific agricultu

Were the ordinary citizens of imperial metropoles during the 19th and 20th centuries arduous supporters or apathetic observers of their country's colonial expansionism, or did their relationship to empire fall somewhere in between? Although this is a central question for understanding the how and why of modern imperialism and evaluating responsibility for colonial wrongs, scholars in the only loos

The study of popular imperialism, or the extent to which the ordinary citizens of an imperial metropole were aware of and supported their country’s imperial expansion, provides a crucial empirical basis for evaluating the causes of and responsibility for colonial aggression. Nevertheless, this topic has received considerably less attention than comparable topics like fascism, genocide or nationali

What trans-imperial connections existed between the French and Japanese Empires? One example that is frequently recounted in Japanese colonial historiography involves the 1895 advice of French legal expert Michel Revon over what administrative system Japan should adopt in Taiwan. According to these accounts, Revon advocated a French assimilationist system for the island in a policy brief that woul