Purpose: Patients with acromegaly have an increased risk of sleep apnea, but reported prevalence rates vary largely. Here we aimed to evaluate the sleep apnea prevalence in a large national cohort of patients with acromegaly, to examine possible risk factors, and to assess the proportion of patients diagnosed with sleep apnea prior to acromegaly diagnosis. Methods: Cross-sectional multicenter stud

This study grounds a highly charged debate on agriculture in developing countries within economic theory, by establishing a structured analytical framework for considering the potential role of foreign investment in supporting agricultural development. The framework is developed to be time and space neutral, such that it can be utilized in various geographic settings and across different time peri

Small cell lung cancer (SCLC) is a neuroendocrine tumour that exhibits rapid growth and metastatic spread. Although SCLC represents a prototypically undifferentiated cancer type, thyroid transcription factor-1 (TTF-1, gene symbol NKX2-1), a master regulator for pulmonary epithelial cell differentiation and lung morphogenesis, is strongly upregulated in this aggressive cancer type. The aim of this

TomoWarp2 is a Python based code that allows full-field vector displacements to be measured between 2D or 3D image sets, based on a local approach of Digital Image Correlation. These displacements can be used to calculate the complete 2D or 3D strain tensor field to study, for example, heterogeneous deformation responses of materials during loading. The code is provided with a GUI, and can handle

Background: Early cartilage changes in knee osteoarthritis (OA) can be assessed by both intravenous (i.v.) and intra-articular (i.a.) delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). Purpose: To examine the relationship between i.a. dGEMRIC and delayed gadolinium-enhanced MRI of menisci (dGEMRIM), and to investigate if the approach can be used to assess the morphological degeneration of men

Objective: We endeavored to create a comprehensive course in global surgery involving multinational exchange. Design: The course involved 2 weeks of didactics, 2 weeks of clinical rotations in a low-resource setting and 1 week for a capstone project. We evaluated our success through knowledge tests, surveys of the students, and surveys of our Zimbabwean hosts. Setting: The didactic portions were h

The success of membrane technology in the food industry is directly linked to the success of membranes in protein recovery. Proteins are one of the most important food ingredients and their global market is growing rapidly. In 2012 the global market of protein accounted for 19 billion USD, while for 2018 it is expected to reach 28 billion USD. The aim of this presentation is to provide an overview

The pulp and paper industry is one of the most important industrial sectors worldwide and has a great potential to be the nucleus for the future bio-economy. Today’ pulp industry is mainly focusing on the production of cellulose fibres and electricity, while its future potential includes the production of bio-chemicals, bio-fuels and advanced materials. In order to fulfil their future role, pulp m

1. INTRODUCTIONFrom the early days of membrane technology fouling has been identified as the most important parameter for the slow integration of technology in the industry [1]. Since then significant progress has been achieved in the field of fouling and cleaning of membranes which are still both key aspects in membrane plant operation in the food and bioprocess industry with a significant impact

De senaste åren har det blivit tydligt att detaljhandeln av idag måste hantera två förändringstryck: ökande internethandel och hållbarhetshänsyn. Hur fristående fysiska butiker och kedjor hanterar dessa tryck kommer att få avgörande betydelse för deras överlevnad. I detta kapitel argumenteras för att det finns en framtid för den fysiska butiken om miljöhänsyn tas på allvar ihop med de möjligheter

With a commitment to a relational ontology, scholars from within the feminist care tradition of animal ethics have been able to theorize how our moral significance - as well as our moral obligations to others - arise from the metaphysical and empathetic 'entanglements. Independent of species, gender and the like, we exist as embodied beings. Sharing a position that originates in nonwestern culture

Glycosaminoglycans (GAGs) are essential polysaccharides in normal physiology and disease. However, understanding of the contribution of specific GAG structures to specific biological functions is limited, largely because of the great structural heterogeneity among GAGs themselves, as well as technical limitations in the structural characterization and chemical synthesis of GAGs. Here we describe a

A typical approach when designing a bio-inspired robot is to simplify an animal model and to enhance the functionality of interest. For hexapod robots, this often leads to a need of supplementary mechanics to become multifunctional. However, a preferable solution is to employ the embodied multifunctional capabilities of the animal as inspiration for robot design. Using this approach, we present a

Background: Lack of a global consensus on the definition of advanced Parkinson’s disease (APD) and considerations for timing of device-aided therapies may result in heterogeneity in care. Objectives: To reach consensus among movement disorder specialists regarding key patient characteristics indicating transition to APD and guiding appropriate use of device-aided therapies in the management of PD

International research has consistently reported that youth in secure residential care have high rates of somatic/dental health problems. Here, we report results from the first such study in a Nordic country. An experienced paediatrician performed systematic somatic and rudimentary dental health assessments of 91 youths, age 13–17, recently admitted to four secure residential units in Sweden. Girl

Introduction: Women who smoke, deliver significantly smaller infants. These infants have reduced levels of the vasodilator endothelial nitric oxide synthase (eNOS) levels in the umbilical vessels, which may reduce fetal growth. Serum cotinine, the degradation product of nicotine, can be used to determine the level of tobacco exposure. Newborns of environmental smokers are suggested to be smaller a