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Purpose: Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods: For the di
The UK Athena SWAN (AS) Charter was extended to Irish Higher Education Institutions (HEIs) in 2015 to provide a catalyst for change towards gender equality and to transform institutional cultures, through AS Gender Action Plans. This paper charts: the journey of Athena SWAN to Ireland; its rate of adoption by Irish HEIs; and its impact on the sector. Drawing upon the perspective and contribution o
Introduction: In mental health physiotherapy, there is a lack of research investigating the assumptions and clinical reasoning strategies of the professionals. A critical view on what is taken for granted within physiotherapy promotes professional development. Purpose: The purpose of this study was to explore and describe the essence of clinical reasoning of Austrian mental health physiotherapists
A source of indoor malodor in older buildings are chloroanisoles, a methylation from chlorophenols. Chlorophenols were commonly used in wood preservatives 50 years ago which were used to treat construction details exposed to high moisture loads. The methylation process requires a methylator in the form of fungi or bacteria in conjunction with adequate growth conditions for said fungi. The food ind
The growing understanding of the increased frequency and severity of extreme weather events due to climate change demands action. Locally, measures to adapt must be taken without knowing exactly what will happen, where it will happen or what the consequences will be. To meet this need, a number of decision support tools have been developed and this article investigates how municipalities can imple
Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm that follows a heterogeneous clinical course. Recurrent mutations have been described, but their applicability in the clinical setting is currently limited. The main reasons are challenges in the sequencing of DNA retrieved from formalin-fixed tissue commonly used for tissue collection in clinical biobanks. In this study, we sequenced 77
In recent years, climate change has been widely recognized as a potential problem. The building industry is taking a variety of actions towards sustainable development and climate change mitigation, such as retrofitting buildings. More than mitigation, it is important to account for climate change adaptation and investigate the probable risks and limits for mitigation strategies. For example, one
The effects of quarl on the non-premixed swirling flames were studied by performing simultaneous OH-PLIF/PIV measurements experimentally and coupling LES with PDF combustion model numerically. The results showed that LES-PDF method can successfully capture the swirl flow fields and flame structures even including local extinction and re-stabilization. Compared to the no quarl case, the quarl plays
It is well-known that the morphology of urban areas modifies the variations of climate variables at microscale; known as microclimate conditions. The complexity of urban morphology can lead to undesired wind conditions or excessive air temperature; particularly in extreme weather conditions. This study attempts to quantify the impacts of urban morphology on the evolution of wind speed and air temp
Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing with castration-resistant prostate cancer. Targeting prostate-specific antigens whose expression is c
Context: In a recent study a pattern of 27 metabolites, including serum glycine, associated with bone mineral density (BMD). Objective: To investigate associations for serum and urinary glycine levels with BMD, bone microstructure, and fracture risk in men. Methods: In the population-based Osteoporotic Fractures in Men (MrOS) Sweden study (men, 69-81 years) serum glycine and BMD were measured at b
Silencing of Chl1 gene expression has been previously reported to reduce insulin secretion. Nevertheless, the mechanism underlying this effect remains unclear. In this study, we performed a serial of studies to investigate how Chl1 affects insulin secretion in INS-1 cells. RNA-sequencing was used to investigate the expression of CHL1 in human adipose, liver, muscle, and human islets. Silencing of
The seabed in the ports needs to be regularly cleaned from the marine sediments for safe navigation. Sediments contaminated by tributyltin (TBT) are environmentally harmful and require treatment before recycling. Treatment methods include leaching, stabilisation and solidification to remove toxic chemicals from the sediments and improve their strength for reuse in the construction works. This stud
Background: Early extensive surgery is a cornerstone in treatment of diffuse low-grade gliomas (DLGGs), and an additional survival benefit has been demonstrated from early radiochemotherapy in selected "high-risk"patients. Still, there are a number of controversies related to DLGG management. The objective of this multicenter population-based cohort study was to explore potential variations in dia
High-density lipoprotein (HDL) functional traits have emerged as relevant elements that may explain HDL antiatherogenic capacity better than HDL cholesterol levels. These properties have been improved in several lifestyle intervention trials. The aim of this systematic review is to summarize the results of such trials of the most commonly used dietary modifications (fatty acids, cholesterol, antio
Background: This analysis of the Observational Postmarketing Ulcerative Colitis Study examined incidence rates of colectomy in patients with ulcerative colitis who received originator infliximab (IFX) or conventional therapies (ConvRx) as per their treating physician. Methods: Cox proportional hazards models compared time to colectomy for both treatment groups. A secondary analysis examined colect
Maternal undernutrition can lead to protein-energy malnutrition, micronutrient deficiencies, or anemia during pregnancy or after birth. It remains a major problem, despite evidence-based maternal-nutrition interventions happening on ground. We conducted a scoping review to under-stand different strategies and delivery mechanisms to improve maternal nutrition, as well as how interventions have impr
Both disturbed sleep and lack of exercise can disrupt metabolism in pregnancy. Accelerometery was used to objectively assess movement during waking (physical activity) and movement during sleeping (sleep disturbance) periods and evaluated relationships with continuous blood glucose variation during pregnancy. Data was analysed prospectively. 15-women without pre-existing diabetes mellitus wore con
Obesity is associated with an increased risk of breast cancer, which is the most common cancer in women worldwide (excluding non‐melanoma skin cancer). Furthermore, breast cancer patients with obesity have an impaired prognosis. Adipose tissue is abundant in the breast. There-fore, breast cancer develops in an adipose‐rich environment. During obesity, changes in the local environment in the breast
