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Hic2 overexpression increase of cell reprogramming efficiency- a computational study
Stamceller är celler som kan omvandlas till vilken celltyp som helst, vilket gör dem mycket användbara inom olika medicinska behandlingar och undersökningar. Stamceller kan exempelvis behandla cancer och diabetes, men skulle även kunna användas till att bota förlamning. Idag pågår det mycket forskning kring hur vanliga celler kan omvandlas till stamceller. Genom att manipulera mängden olika transkSince stem cells have many applications in medicine and can be used for treating e.g. cancer and diabetes, finding efficient methods for producing them is a relevant area of research. Cell reprogramming is such a method and our collaborators recently showed that adding Hic2 to the existing protocols of methods increases the efficiency from 1% to 10%. In this thesis, I aim to investigate how an add
Valcykelns påverkan på resultatmanipulation i svenska kommuner
The Selective Activation of The Anomeric Position in Unprotected Sugars
De flesta är medvetna om kolhydraters betydelse som näringsämnen och energikälla, men vad många förmodligen inte känner till är att kolhydrater är viktiga byggstenar i kroppen då de binder till olika proteiner och lipider och bildar så kallade glykoproteiner och glykolipider som finns bland annat i våra cellmembran. En viktig klass av kolhydrater är glykosider som består av en sockerdel som kallasThe one-step conversion of unprotected sugars to sugar intermediates invented by the Shin-ichiro Shoda group at Tohoku University in Japan by using 2-chloro-1,3-dimethyl-imidazolinium chloride (DMC) as a dehydrative condensing agent is a relatively new way to synthesize carbohydrate derivatives. A great effort has been done to investigate the minimum requirement of bases, the suitable dehydrative
#Slutakidnappavårabarn - En innehållsanalys om hur användare på forumet Flashback kan bidra till desinformation om svenska socialtjänsten
The purpose of this study was to examine disinformation regarding Swedish Child Protective Services in the online forum Flashback through a constructivist perspective with a focus on conspiracy theories regarding the subject. The study is an internet-based study with a netnographic approach. The focus was to analyze the unfounded claims that the Swedish social services wrongfully apprehend childre
Properties & Stability of Hybrid Pea-Dairy Protein Formulas
The aim of this study was to investigate the functional properties and stability of hybrid pea-dairy protein formulas. To achieve this goal, the combination of pea protein isolate (PPI) with dairy proteins such as micellar casein isolate (MCI), sodium caseinate (NaCas), whey protein aggregate (WPA) was evaluated. Samples stored for 2 and 4 weeks at 4oC and 20oC were visually assessed and physicoch
Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis
Kan hemoglobin från växter lösa humana problem? Dagligen tar vi för givet att vårt blod syresätts tillräckligt för att orka med alla sysslor. Detta möjliggörs av det livsviktiga proteinet hemoglobin som finns i vårt blod. I dagens samhälle råder det dock blodbrist samtidigt som många drabbas av järnbrist. Det är där forskningen på växthemoglobin kommer in i bilden. Experimenten som genomförts i dThe protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. A few years ago, genes that code for Pgb in sugar beet were found and ident
Exposure of LDPE nanoplastics of different fractions to Daphnia magna
Små partiklar från nedbrytning av plasten polyeten kan leda till ytterligare miljöutmaningar Plast produceras idag i stor omfattning och en stor del av plasten som används hamnar i naturen. När plasten bryts ned till mindre partiklar av bland annat mekaniska påfrestningar och UV ljus, kan dessa ta sig in i vävnader hos djur och människor och orsaka skada. I vilken utsträckning dessa partiklar påvePlastic pollution is an urgent environmental problem. Plastic can break down in nature into micro- and nanoplastics, and the impacts of these, and especially nanoplastics on the environment are not fully understood. Particles have been shown to accumulate in tissues of animals, where they are believed to cause cell damage. In this project, LDPE was broken down, filtered to obtain nanoplastics, sep
Being queer means being political. A Qualitative study of Queer Activists Lived Experiences and the Silent Support in Contemporary Poland
For the fourth year in a row, Poland continues to rank as the lowest country of the European Union on the yearly report on the legal and political situation of queer people in Europe. With constant negative media portrayal of queer communities and homophobic remarks from politicians, Polish queer individuals become antagonized and stigmatized by the society. This thesis aims to explore the less re
Damage Analysis of Reactive Ion and Atomic Layer Etched Silicon
Dry etching is one of the most important methods of pattern transfer in nanofabrication. There are many dry etching methods, the most commonly used is reactive ion etching (RIE), that is based on a continuous supply of reactive ions and radicals generated in a radio-frequency (RF) plasma discharge. The RIE approach can be very accurate and may provide high resolution etching, below 10 nm in latera
Barntolken - En kvalitativ studie om barn som tolkar i möten med professionella
It is known that the phenomenon of child language brokering, where children act as interpreters for family members, exists in Sweden. Several studies have shown problematic aspects of the practice. The aim of this study was to explore young adults' experiences of child language brokering in appointments with professionals. The method chosen for this study was qualitative interviews with nine y
Breaking the Stereotypes: Exploring Control and Self-Expression of Modern-Day Freak Show Performers
Abstract Author: Dana Štěpánková Title: Breaking the Stereotypes: Exploring Control and Self-Expression of ModernDay Freak Show Performers Supervisor: Sébastien Tutenges Master’s Thesis SOCM04, Cultural Criminology, 30 credits Department of Sociology, Spring 2023 Freak shows have been historically depicted as dehumanizing spectacles exhibiting individuals with physical anomalies. Over time, these
Det mänskliga och det organisatoriska: Human Resources - en tudelad roll
HR-yrket är i ständig förändring och upplever i dagsläget ett stort intresse från organisationer runt om i landet för deras många kompetensområden. Med detta i åtanke är det av vikt att HR-funktionen bemöts på rätt sätt och har de verktyg som behövs för att kunna prestera. Denna studie ämnar därför att besvara två frågor: vilka krav och förväntningar existerar på HR-praktiker från olika sidor av o
Discussion of Python Implementation Techniques for Discontinuous Galerkin Methods
This paper discusses implementation techniques for integration methods within the Discontinuous Galerkin Methods. These methods are used to approximate solutions for differential equations. To do so, one must compute a polynomial, which is an approximation of the used function. To compute this approximation, orthogonal polynomials, chosen to be the Legendre polynomials are used, as well as integra
Hydraulic Modelling of Eurasian Beaver Structural Modifications: Implications for Evaluating their Contributions to Natural Flood Management in Scotland
The concurrent climate and biodiversity crises in Scotland necessitate the exploration of ecosystem-based adaptation to simultaneously address increased flood risk and the loss of native species. This research investigated the contributions of Eurasian beaver reintroductions to natural flood management in Scotland. It did this by reviewing the relevant literature on the primary structural modifica
Integrating Waste Heat from Hydrogen Production Into District Heating
The aim of this research is to explore the feasibility of the integration of waste heat from electrolyzers within a Combined Heat and Power (CHP) plant and district heating (DH) network and suggest a practical setup for integration. With the escalating emphasis on the development of green hydrogen through electrolysis powered by renewable energy, a substantial amount of waste heat is generated, ty
Inventory management: A high-level analysis of selected process elements, and factors impacting plan performance - A case study at Alfa Laval
Purpose: The purpose of this thesis is to increase the effectiveness of the case company, Alfa Laval’s, inventory management by finding challenges, opportunities, and gaps within its current inventory management practices. Background: An essential part of an organization’s planning and control is inventory management, which helps manage supply and demand uncertainty as well as mismatches in upst
Ukrainian Refugee Women as The Subject of Images and Discourses in Swedish and Ukrainian Media
Russia's full-scale invasion of Ukraine on February 24, 2022, resulted in a substantial displacement of people, most of whom were Ukrainian women and children. Given the vast number of Ukrainian refugees who have fled to other countries, the aim was to examine how the news media portrays their images and experiences. This master's thesis focuses on identifying representations of Ukrainian
Phase Transitions in the Two-Higgs-Doublet Model with a Softly-Broken Z2 Symmetry
Efter upptäckten av Higgspartikeln vid CERN 2012 har alla partiklar i standardmodellen för partikelfysik upptäckts. En intressant frågeställning är då för vilka processor inom fysiken som standardmodellen är bristfällig och inte ger tillfredsställande svar. Fysik som försöker utvidga partikelfysiken till mer än standardmodellen i hoppet om att kunna ge svar på dessa frågor kallas fysik bortom stanThe two-Higgs-doublet model (2HDM) is an extension to the Standard Model which adds a second Higgs doublet. This extension provides freedom within the model, in comparison to the Standard Model, which makes it possible to study strong electroweak phase transitions. These can provide an explanation for the matter-antimatter asymmetry through the Sakharov conditions, three conditions that leads to c
Hostile Sexism and The Acceptance of Rape Myths: The Role of Masculinity Threat in Two Salient Predictors of Sexual Violence
This thesis aimed to investigate the association between masculinity threat and two salient predictors of sexual assault: hostile sexism and rape myth acceptance. The thesis comprised two studies. Study 1 focused on the correlational relationships between three measures of masculinity threat (masculine contingency, gender role discrepancy stress, and status threat) and the two predictors of sexual