Popular Abstract in Swedish Livstidsprevalensen för läkemedelsberoende hos alkoholberoende patienter varierar mellan 20% och 45%. I normalbefolkningen är livstidsprevalensen av läkemedelsberoende cirka 2%; livstidsprevalensen för beroende av bensodiazepiner (BZD) respektive legala opioider (metadon exkluderat) är 0.3-0.9% respektive 0.8%. Förskrivningen av BZD har de senaste åren legat konstant elThe thesis contains 4 papers, two clinical studies and two meta-analyses. In the BZD taper study (Paper I) 21 BZD dependent (DSM-IV) patients were included for a 10-day inpatient detoxification. The average defined daily dose (DDD) was 4.7 doses. Withdrawal symptoms were not more pronounced compared to more extended detoxification procedures reported in literature. Five patients, all with concomi

Introduction. An open collaborative international network has been established which aims to improve inter-centre standards for collection of high-resolution, neurointensive care data on patients with traumatic brain injury. The group is also working towards the creation of an open access, detailed and validated database that will be useful for post-hoc hypothesis testing. In Part A, the underlyin

Diethylhexyl phthalate (DEHP) is widely used as a plasticizer in consumer products and is known to disturb the development of the male reproductive system in rats. The mechanisms by which DEHP exerts these effects are not yet fully elucidated, though some of the effects are related to reduced fetal testosterone production. The present study investigated the effects of four different doses of DEHP

By means of atomistic molecular dynamics simulations, we study cholesterol-DPPC (dipalmitoyl phosphatidylcholine) bilayers of different composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol. The lateral pressure profiles through the bilayers are computed and separated into contributions from the different components. We find that the pressure inside the bilayer changes qual

In this thesis we present new worst case computational bounds on algorithms for some of the most well-known NP-complete and #P-complete problems and their optimization variants. We consider graph problems like Longest Path, Maximum Cut, Number of Perfect Matchings, Chromatic and Domatic Number, as well as Maximum k-Satisfiability and Set Cover. Our results include I a) There is a polynomial--

Background: Lack of generalized guidelines for DNA flow cytometric analysis (FCM) may be the main reason for its limited use in the clinical management of breast cancer. Methods: After an initial interlaboratory reproducibility study (Round 1), we concluded that it was the evaluation of the DNA histograms rather than the technical performance of the analysis that was the main reason for discordant

The structure of the N=Z nuclei Zn-60, Ga-62, Ge-64 and Kr-72 has been investigated at GASP spectrometer through the S-32 + Ca-40 and Ca-40 + Ca-40 reactions at 140 and 160 MeV, respectively, using reaction channel selection with the ISIS Si-ball. The high spin states of such nuclei have been investigated searching for the four quasi-particle g(9/2) alignment. TRS calculations have been performed

Popular Abstract in Swedish Avhandlingen beskriver och analyserar hur människor som arbetar i ett företag som blir uppköpt upplever uppköpsprocessen. Författaren lyfter fram de många olika tolkningar och upplevelser som finns av uppköpet istället för att ge en homogen återgivning. Författaren hävdar att för att kunna förstå vad som händer i ett företag under en uppköpsprocess så måste man beakta dWhile the human side of mergers and acquisitions is increasingly focused in both research and practice, it still suffers from several forms of oversimplifications. This study addresses the problem of how various employees interpret objectives, corporate identity and other meanings associated with the post-acquisition process, and what roles these multiple interpretations play during this critical

BACKGROUND AND OBJECTIVES: Atherosclerosis is a multifactorial disease, in part characterized by chronic inflammatory changes in the vessel wall and loss of normal physical and biochemical interactions between endothelial cells and smooth muscle cells. Previous studies [Hu J., Cotgreave IA. J Clin Invest; 99: 1-5] have provided molecular links between inflammation and myoendothelial communication

Objectives: The associations between vertical ( institutional) trust in the healthcare system and the mass media ( newspapers and television), and daily smoking and smoking cessation were investigated. Methods: The 2004 public-health survey in Scania is a cross-sectional study. A total of 27,757 persons aged 18-80 years answered a postal questionnaire, which represents 59% of the random sample. A

Cooperative communications, where parallel relays forward information to a destination node, can greatly improve the energy efficiency and latency in ad-hoc networks. However, current networks do not fully exploit its potential as they only use traditional energy-accumulation, which is often used in conjunction with repetition coding or cooperative space-time codes. In this paper, we show that the

The CP conserving amplitudes for the decays K --> 3pi are calculated in Chiral Perturbation Theory. The calculation is made at the next-to-leading order including strong and local electromagnetic isospin breaking. A comparison is made between the squared amplitudes with and without isospin violation to estimate the size of the effect. We find corrections of order five percent in the amplitudes.