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Innovating but still poor : The challenges of regional development in regions with mature industries

The persistence of patterns of decline or stagnation in developed countries has led to a renewed interest in the study of less developed regions. This renewed interest is informed by a variety of approaches, which range from studies on the unequal distribution of economic power and resources to analysis of regional endowments, such as human capital or quality of institutions. However, a persistent

Drug use disorder and risk of incident and fatal prostate cancer among Swedish men : a nationwide epidemiological study

Purpose: Prostate cancer is the second most common cancer in men and a leading cause of cancer mortality worldwide. Men with drug use disorders (DUD) may potentially be at high risk for prostate cancer mortality because of delayed diagnosis and/or undertreatment. In this study, we aimed to investigate prostate cancer incidence, mortality, and stage at time of diagnosis among men with DUD compared

Stillbirth or neonatal death before 45 post-menstrual weeks in relation to gestational duration in pregnancies at 39 weeks of gestation or beyond : the impact of parity and body mass index. A national cohort study

Objective: To investigate the risk of stillbirth or neonatal death before 45 post-menstrual weeks in relation to gestational duration, stratified by body mass index (BMI) and parity. Design: Retrospective study. Setting: Data from the Swedish Medical Birth Register. Population: Singleton, cephalic births at between 39+0 and 42+2 weeks of gestation, 2005–2016 (n = 892 339). Methods: Relative risk r

Implementing an occupational therapy specific mental health intervention in a multi-professional context–the case of Balancing Everyday Life (BEL)

Background: The occupation-based intervention Balancing Everyday Life (BEL) was found effective under controlled conditions but should also be studied in a natural clinical practice context. Aim: The aim was to study the implementation process of BEL when provided in a multi-professional mental health team. The focus was particularly on how BEL was received and functioned. Methods: This qualitativ

Stratification strength and light climate explain variation in chlorophyll a at the continental scale in a European multilake survey in a heatwave summer

To determine the drivers of phytoplankton biomass, we collected standardized morphometric, physical, and biological data in 230 lakes across the Mediterranean, Continental, and Boreal climatic zones of the European continent. Multilinear regression models tested on this snapshot of mostly eutrophic lakes (median total phosphorus [TP] = 0.06 and total nitrogen [TN] = 0.7 mg L−1), and its subsets (2

Clinical and biological impact of SAMHD1 expression in mantle cell lymphoma

SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (dNTPase) that restricts viral replication in infected cells and limits the sensitivity to cytarabine by hydrolysing its active metabolite, as recently shown in acute myeloid leukemia. Cytarabine is an essential component in the Nordic mantle cell lymphoma protocols (MCL2 and MCL3) for induction and high-dose chemotherapy treatment befor

Digital Entry-Level Education in Physiotherapy : a Commentary to Inform Post-COVID-19 Future Directions

Currently, the coronavirus disease 2019 (COVID-19) severely influences physiotherapy education which is based mostly on face-to-face teaching. Thus, educators have been compelled to adapt their pedagogical approaches moving to digital education. In this commentary, we debate on digital education highlighting its effectiveness, the users’ perspectives, and its weakness in the context of physiothera

The role of circulating galectin-1 in type 2 diabetes and chronic kidney disease : evidence from cross-sectional, longitudinal and Mendelian randomisation analyses

Aims/hypothesis: Galectin-1 modulates inflammation and angiogenesis, and cross-sectional studies indicate that galectin-1 may be a uniting factor between obesity, type 2 diabetes and kidney function. We examined whether circulating galectin-1 can predict incidence of chronic kidney disease (CKD) and type 2 diabetes in a middle-aged population, and if Mendelian randomisation (MR) can provide eviden

Challenges and Strategies for Managing Requirements Selection in Software Ecosystems

In platform software ecosystems, organizations partner and innovate together. Success and innovation depend on managing complex sets of business relationships and stakeholders and using a requirements-selection process. We describe the associated challenges and strategies from the study of two large proprietary platform ecosystems.

Trustworthy faces make people more risk-tolerant : The effect of facial trustworthiness on risk decision-making under gain and loss conditions

People can judge a stranger's trustworthiness at first glance solely based on facial appearance. Moreover, the trust behaviors people exhibit toward strangers differ depending on perceived trustworthiness from faces. Research has found that people have different risk preferences according to the gain or loss frame. Therefore, we hypothesized that the risk decisions are differently affected by faci

Reception through Polemics : The Internalization of Theological Otherness in Jerome's Heresiology

Early Christian heresiology is, like polemics in general, a genre that has commonly been negatively perceived in scholarship. There is an idea of heresiological texts as not only historically unreliable, but also unproductive, in contrast to the creative thinking that can be found in theological treatises. Considering the understanding of heresiology as reactive and exclusive, it is not surprising

High-resolution source localization exploiting the sparsity of the beamforming map

Beamforming technology plays a significant role in source localization and quantification. As traditional delay-and-sum beamformers generally yield low spatial resolution, as well as suffer from the occurrence of spurious sources, different forms of deconvolution methods have been proposed in the literature. In this work, we propose two approaches based on a sparse reconstruction framework combine

Exponential Set-Point Stabilization of Underactuated Vehicles Moving in Three-Dimensional Space

This paper investigates the stabilization of underactuated vehicles moving in a three-dimensional vector space. The vehicle's model is established on the matrix Lie group SE(3), which describes the configuration of rigid bodies globally and uniquely. We focus on the kinematic model of the underactuated vehicle, which features an underactuation form that has no sway and heave velocity. To compensat

Life satisfaction and coronary atherosclerosis : The SCAPIS study

Background: There is an increasing interest in the potential health benefits of positive psychological states, especially with regard to cardiovascular health. Life satisfaction is thought to be a constituent component of psychological well-being; however, among the few previous studies that have investigated its associations with early stages of the cardiovascular disease process, only one small

Interaction-context schema : A proposed model to support interaction analysis in small and medium enterprises

Information Systems Interactions are a pivotal point in developing an understanding of a socio-technical system. From this perspective, Information Systems could be defined as the cooperation, coexistence and integration of a socio-technical approach with the social aspect. This research investigates how people communicate in a business and how this is likely to support knowledge sharing practices

Motives behind ddos attacks

Behind everything we do in our daily lives there is a reason for doing it. This paper looks into the motives behind DDoS attacks as a form of cyberattack along with attacker personas. This paper also investigates DDoS attacks technically and it is suggested that there is a need for a socio-technical approach to these attacks to investigate why they occur and the reasoning the attacker(s) could hav