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Dialogue in the making : Emotional engagement with materials

Taking a psychological and philosophical outlook, we approach making as an embodied and embedded skill via the skilled artisan’s experience of having a corporeal, nonlinguistic dialogue with the material while working with it. We investigate the dynamic relation between maker and material through the lens of pottery as illustrated by wheel throwing, claiming that the experience of dialogue signals

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This article explores the international treaty base of the diplomatic law of international organizations and its role in protecting personnel of international organizations. The main diplomatic treaties and conventions, the participation of Uzbekistan in these treaties and conventions, as well as their role in the protection of diplomatic staff of international organizations were reviewed.

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This article examines the legal content and frameworks of the application of the privileges and immunities of the representative offices of international organizations in member states. It contains a detailed analysis and deliberation of the legal basis of privileges and immunities of representative offices of international organizations in Member States. The article tries to clarify and highlight

Digital Ekphrasis : Through the Digital

In the light of the digital influence of literature and art, my paper focuses on a rather small topic that is traditionally strongly placed in the aesthetics of the interart and intermedia discourse, namely ekphrasis. Whereas the conventional discourse outlines ekphrasis as a “verbal representation of a visual representation” (Hefferan 1993, p. 3) to call attention to poems describing paintings, m

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This article examines the models of informal payment of wages by individual employers with the aim to avoid taxation. It will also analyze the causes and consequences of this phenomenon and the effect of the “colour” of income on the well-being of an employee, an employer and the state as a whole. In addition, the article identifies possible solutions to the problem of hidden wages. It also discus

A strip-yield rate-dependent model for rapid loading conditions

In order to obtain quantitative information of the effects of rate dependent plasticity on crack growth initiation, a strip yield (Dugdale) model for small-scale yielding is developed. The adopted rate dependence of the flow stress is of the Perzyna type. Numerical solutions are obtained for different KI(t) functions. By adopting both a displacement-criterion and a stress-criterion for crack growt

Memory and communication as poetic stimulants

In 2013, American poet and academic Ange Mlinko published her third volume: Marvelous Things Overheard. As in her second volume, Shoulder Season, 2010, Mlinko mingles epochs and geographies in an effort to listen to and comprehend those human voices resounding mainly from conflictual areas. There is no communication without memory. That is why the poetess embodies languages, sorrows, happy feeling

Stable and unstable growth of crack tip precipitates

A model is established that describes stress driven diffusion, resulting in formation and growth of an expanded precipitate at the tip of a crack. The new phase is transversely isotropic. A finite element method is used and the results are compared with a simplified analytical theory. A stress criterium for formation of the precipitate is derived by direct integration of the Einstein-Smoluchowski

Artistic symbols as support of a biased imagination

Ian McEwan has indulged in macabre plots whose point of interest resided in the power of imaginary over the allegedly rational reality. In novels like Atonement, Enduring Love, On Chesil Beach and Amsterdam he pointed out how approaching the world scientifically can be as misleading as doing it on the religious or literary ways. The target of my paper is to spot those common places of fanaticism a

β Decay of 127Cd and Excited States in 127In

A dedicated spectroscopic study of the β decay of 127Cd was conducted at the IGISOL facility at the University of Jyväskylä. Following high-resolution mass separation in a Penning trap, β-γ-γ coincidences were used to considerably extend the decay scheme of 127In. The β-decaying 3/2+ and 11/2- states in 127Cd have been identified with the 127Cd ground state and the 283-keV isomer. Their respective

Effect of Alloying with Rare-Earth Metals on the Degradation of Magnesium Alloys Studied Using a Combination of Isothermal Calorimetry and Pressure Measurements

With all the versatility in structural performance and recent progress in developing magnesium alloys, their Achilles heel remains to be degradation or corrosion property. While applications in mobility demand corrosion protection by all means, bio-medical applications of Mg alloys require well-controlled degradation rates. Meeting these requirements is only possible through the understanding of p

Towards knowledge-based geovisualisation using Semantic Web technologies : a knowledge representation approach coupling ontologies and rules

Geovisualisation is a knowledge-intensive art in which both providers and users need to possess a wide range of knowledge. Current syntactic approaches to presenting visualisation information lack semantics on the one hand, and on the other hand are too bespoke. Such limitations impede the transfer, interpretation, and reuse of the geovisualisation knowledge. In this paper, we propose a knowledge-

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

To sustain their proliferation, cancer cells become dependent on one-carbon metabolism to support purine and thymidylate synthesis. Indeed, one of the most highly upregulated enzymes during neoplastic transformation is MTHFD2, a mitochondrial methylenetetrahydrofolate dehydrogenase and cyclohydrolase involved in one-carbon metabolism. Because MTHFD2 is expressed normally only during embryonic deve

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

Thiopurines are a standard treatment for childhood leukemia, but like all chemotherapeutics, their use is limited by inherent or acquired resistance in patients. Recently, the nucleoside diphosphate hydrolase NUDT15 has received attention on the basis of its ability to hydrolyze the thiopurine effector metabolites 6-thio-deoxyGTP (6-thio-dGTP) and 6-thio-GTP, thereby limiting the efficacy of thiop

Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A

The highly poisonous botulinum neurotoxins, produced by the bacterium Clostridium botulinum, act on their hosts by a high-affinity association to two receptors on neuronal cell surfaces as the first step of invasion. The glycan motifs of gangliosides serve as initial coreceptors for these protein complexes, whereby a membrane protein receptor is bound. Herein we set out to characterize the carbohy

Extending the scope of dispersive liquid–liquid microextraction for trace analysis of 3-methyl-1,2,3-butanetricarboxylic acid in atmospheric aerosols leading to the discovery of iron(III) complexes

3-Methyl-1,2,3-butanetricarboxylic acid (MBTCA) is a secondary organic aerosol and can be used as a unique emission marker of biogenic emissions of monoterpenes. Seasonal variations and differences in vegetation cover around the world may lead to low atmospheric MBTCA concentrations, in many cases too low to be measured. Hence, an important tool to quantify the contribution of terrestrial vegetat

A method for analyzing stakeholders’ influence on an open source software ecosystem’s requirements engineering process

For a firm in an open source software (OSS) ecosystem, the requirements engineering (RE) process is rather multifaceted. Apart from its typical RE process, there is a competing process, external to the firm and inherent to the firm’s ecosystem. When trying to impose an agenda in competition with other firms, and aiming to align internal product planning with the ecosystem’s RE process, firms need

A Community Strategy Framework – How to obtain influence on requirements in meritocratic open source software communities?

Context: In the Requirements Engineering (RE) process of an Open Source Software (OSS) community, an involved firm is a stakeholder among many. Conflicting agendas may create miss-alignment with the firm's internal requirements strategy. In communities with meritocratic governance or with aspects thereof, a firm has the opportunity to affect the RE process in line with their own agenda by gaining