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Effect of CNTF and calcium-ionophore A23187-induced death in cultured embryonic stratal neurons

Petersén Å and Brundin P.Experimental Neurology 160: 402-412 (1999)AbstractCiliary neurotrophic factor (CNTF) has a protective effect on the striatum in animal models of Huntington's disease. However, the mechanism through which it exerts its effect is not clear. In this study, we show that there is a concentration-dependent direct protective effect of CNTF against N-methyl-D-aspartate-mediated ex

https://www.huntington-research.lu.se/effect-cntf-and-calcium-ionophore-a23187-induced-death-cultured-embryonic-stratal-neurons - 2026-08-13

Recent advances on the pathogenesis of Huntington's disease

Petersén Å, Mani K and Brundin P.Experimental Neurology 157: 1-18 (1999)AbstractWe review recent advances regarding the pathogenesis of Huntington's disease (HD). This genetic neurodegenerative disorder is caused by an expanded CAG repeat in a gene coding for a protein, with unknown function, called huntingtin. There is selective death of striatal and cortical neurons. Both in patients and a trans

https://www.huntington-research.lu.se/recent-advances-pathogenesis-huntingtons-disease - 2026-08-13

SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease

Baldo B, Gabery S, Soylu-Kucharz R, Cheong RY, Henningsen JB, Englund E, McLean C, Kirik D, Halliday G and Petersén Å.Neuropathology and Applied Neurobiology 45 (4): 361-379 (2019)AbstractAIMS:Metabolic dysfunction is involved in modulating the disease process in Huntington disease (HD) but the underlying mechanisms are not known. The aim of this study was to investigate if the metabolic regulator

https://www.huntington-research.lu.se/sirt1-increased-affected-brain-regions-and-hypothalamic-metabolic-pathways-are-altered-huntington - 2026-08-13

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA and Jakobsson J.Cell Reports 24(6): 1397-1406 (2018)AbstractMany neurodegenerative diseases are characterized by the presence of intracellular protein aggregates, resulting in alterations in autophagy. However, the consequences o

https://www.huntington-research.lu.se/huntingtin-aggregation-impairs-autophagy-leading-argonaute-2-accumulation-and-global-microrna - 2026-08-13

Microstructural white matter alterations and hippocampal volumes are associated with cognitive deficits in craniopharyngioma

Fjalldal S, Follin C, Svärd D, Rylander L, Gabery S, Petersen Å, Van Westen D, Sundgren P, Bjorkman-Burtscher I, Lätt J, Ekman B, Johanson A and Erfurth EM.European Journal of Endocrinology 178 (6): 577-587 (2018)AbstractCONTEXT:Patients with craniopharyngioma (CP) and hypothalamic lesions (HL) have cognitive deficits. Which neural pathways are affected is unknown.OBJECTIVE:To determine whether th

https://www.huntington-research.lu.se/microstructural-white-matter-alterations-and-hippocampal-volumes-are-associated-cognitive-deficits - 2026-08-13

Laminin α1 reduces muscular dystrophy in dy2J mice

Gawlik KI1, Harandi VM2, Cheong RY3, Petersén Å3, Durbeej M2.1Muscle Biology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.2Muscle Biology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.3Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.Matrix Biology 70: 36-79 (20

https://www.huntington-research.lu.se/laminin-a1-reduces-muscular-dystrophy-dy2j-mice - 2026-08-13

Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism

Vercruysse P, Vieau D, Blum D, Petersén Å and Dupuis L.Frontiers in Molecular Neuroscience 11:2 (2018)AbstractNeurodegenerative diseases (NDDs) are disorders characterized by progressive deterioration of brain structure and function. Selective neuronal populations are affected leading to symptoms which are prominently motor in amyotrophic lateral sclerosis (ALS) or Huntington's disease (HD), or co

https://www.huntington-research.lu.se/hypothalamic-alterations-neurodegenerative-diseases-and-their-relation-abnormal-energy-metabolism - 2026-08-13

Funding

Please note, that all links on this page open a new webpage. Knut and Alice Wallenberg FoundationThrough the research program Wallenberg Clinical Scholars, the Knut and Alice Wallenberg Foundation are funding 24 of the foremost clinical researchers in Sweden. Almost SEK 800 million are used for funding over ten years. Åsa Petersén was appointed Wallenberg Clinical Scholar 2020 and will receive SEK

https://www.huntington-research.lu.se/funding - 2026-08-13

Staff

Here you will find contact information for all the staff working at the Social Sciences Faculty Library. Lina Ahlgren Librarian Email: lina [dot] ahlgren [at] sambib [dot] lu [dot] se Telephone: +46 46 222 09 98 Subject librarian for Psychology and Gender Studies. Filip Astner Librarian Email: filip [dot] astner [at] ch [dot] lu [dot] se Telephone: 042-35 65 23 Research service support. Gustav Dah

https://www.sam.lu.se/en/library/visit-and-contact-us/staff - 2026-08-13

Education

Are you interested in social and behavioural sciences? Here you can find information about our programmes and courses, and what international opportunities there are during your studies. Our programmes and courses Study at a world top 100 university Exchange studies Incoming and outgoing exchange studies Doctoral studies

https://www.sam.lu.se/en/education - 2026-08-13

Purchasing suggestions

You are welcome to submit suggestions for books, journals and databases which you think the library should have. First ensure that we do not have the book or journal by searching in the libraries' search tool Finn. Finn - The Libraries' Search Tool If you have not been able to find the book or journal fill in the form below. The book/journal may be purchased in electronic format.How long does it t

https://www.sam.lu.se/en/form/purchasing-suggestions - 2026-08-13

Book a librarian

If you are a student at the Faculty of Social Sciences, you can book an appointment with a librarian using our form. Fill in the booking form and we will contact you as soon as possible. What course are you taking? Type the course code or the name of the course. Department (required) - Select - Department of Communication Department of Human Geography and the Human Ecology Division Department of P

https://www.sam.lu.se/en/form/book-librarian - 2026-08-13

Career Workshop

Welcome to Career Workshop - The importance of social scientists in the future job market and how to develop professional skills for a sustainable future. If you have registered but are unable to attend, please contact Anna Hjalmers Mattsson (anna [dot] hjalmers_mattsson [at] psy [dot] lu [dot] se) as soon as possible so that someone else can have your place. The seats are limited.Registration for

https://www.sam.lu.se/en/form/career-workshop - 2026-08-13

Copying and printing

Location of the multiprintersEdenGround floor, in the lobbyGamla barnsjukhuset (Sambib)1st floor, end of the left corridorGround floor, "Södra boksalen"Ground floor, "Norra boksalen"Basement, classroomGamla köketBasementGeocentrum 11st floor, 212Campus HelsingborgInformation about the printers at Campus Helsingborg - ch.lu.seCopying and printing with PaperCutTo print or copy with PaperCut, you nee

https://www.sam.lu.se/en/education/current-students/copying-and-printing - 2026-08-13

Book a computer to use in class

Students at the Social Sciences Faculty in Lund, unable to bring a laptop of their own, can apply to borrow a computer for classes that require a computer. Please note that the computer can only be connected to a local network available in the lecture halls on campus. It cannot be used in any other location.Software on the computersArcGisArcGisProDjVuEndnoteGephiJamoviJASPNvivoRR-studioSPSSSPSS Am

https://www.sam.lu.se/en/form/book-computer-use-class - 2026-08-13

Forskning

Nobelpriset 2023 Professor Anne L’Huillier, vid avdelningen för atomfysik på fysiska institutionen, belönades med Nobelpriset i fysik 2023 tillsammans med Pierre Agostini och Ferenc Krausz för deras experiment som gett mänskligheten nya verktyg för att utforska elektronernas värld inuti atomer och molekyler.Mer om Nobelpriset och Anne L´Hullier på LTH:s webbplats. Våra forskningsavdelningar Astrof

https://www.fysik.lu.se/forskning - 2026-08-13

start

Allt är fysik - jakten på svar fortsätter Vår forskning Ett brett spektrum av modern fysik Kontakta en forskare Våra forskare i Lunds universitets forskningsportal Ny som student? Information om höstterminen 2026 Jobba hos oss Lediga tjänster vid fysiska institutionen Kalendarium Länk till RSS 4 september 2026 09:15 till 12:00 | Disputation Patrik Nilsson 4 september 2026 09:15 till 12:00 | Disser

https://www.fysik.lu.se/start - 2026-08-13

Samverkan med skolan

Vad roligt att du är intresserad av fysik! Fysiska institutionen har en rad aktiviteter för dig som går i skolan och är nyfiken på fysik som vetenskapligt ämne. Vi har aktiviteter för både barn, ungdomar och deras lärare. Välkommen att ta del av vår spännande värld! Fysik & lasershow Fysik & lasershowen är fysiska institutionens alldeles egna spektakulära show som ger mer än ett smakprov på hur sp

https://www.fysik.lu.se/fysik-alla/samverkan-med-skolan - 2026-08-13

Fysik & lasershowens historia

Den som först tänkte igenom kombinationen fysik- och lasershow var Per Olof Zetterberg, PO. Tillsammans med teknikern Björn Hansson hade han vid ett tillfälle i mitten av 90-talet visat just fysikexperiment samt lite små trix med några lasrar och lite rök i Borlänge på en studiedag för lärare. Under den första terminen då man läser fysik vid Naturvetenskaplig fakultet har man en seminarievecka då

https://www.fysik.lu.se/samverkan/skolor-och-allmanhet/fysik-lasershow/fysik-lasershowens-historia - 2026-08-13