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Botnia

The Botnia study was initiated in 1990 on the western coast of Finland in the Gulf of Bothnia with the aim to:Characterize the early metabolic defects in individuals at risk of developing type 2 diabetesIdentify genetic variants predisposing to type 2 diabetesStudy how the identified genetic markers and biomarkers can predict the development of type 2 diabetes and progression of the diseaseIdentif

https://www.ludc.lu.se/botnia - 2025-08-19

LUDC-IRC

Lund University Diabetes Centre Industrial Research Centre (LUDC-IRC) is an Industrial Research Centre for personalized medicine in diabetes.Vision: The right prevention and treatment, for the right patients at the right time.Mission: A holistic approach towards improved diagnosis, prevention and treatment of diabetes.Funding (2017-2024): 75 MSEK from SSF. 25 MSEK from industrial partners.Number o

https://www.ludc.lu.se/ludc-irc - 2025-08-19

ANDiS

ANDiS (All New Diabetics in Scania) is a regional research project in southern Sweden. The population of the region is just over one million. All newly diagnosed patients at all ages in the Scania region will be included during 2009-2013.The aim of the registry is to describe the spectrum of diabetes subgroups in southern Sweden and to link genetic and phenotypic information at diagnosis of diabet

https://www.ludc.lu.se/andis - 2025-08-19

Jones Ofori

Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis Type 2 diabetes (T2D) is a complex polygenic disease influenced by both environmental and genetic factors resulting in impaired insulin release from pancreatic beta cells and insulin resistance in target tissues. The incidence of T2D is escalating and it is projected that over 640 million people will

https://www.ludc.lu.se/education-training/theses/theses-2017/jones-ofori - 2025-08-19

Geeti Arora

Gestational Diabetes Mellitus in North India Gestational diabetes mellitus(GDM) defines an unhealthy state of hyperglycaemia that develops in response to an otherwise normal physiological adaptive insulin resistance state during pregnancy. However, the exact plasma glucose levels differentiating the unhealthy GDM state from a normal pregnancy is unknown, and relies upon arbitrary cut off criteria

https://www.ludc.lu.se/education-training/theses/theses-2017/gestational-diabetes-mellitus-north-india - 2025-08-19

Liliya Shcherbina

The role of cocaine- and amphetamine-regulated transcript in endocrine cells Type 2 diabetes (T2D) is a metabolic disease characterized by insufficient insulin secretion and insulin resistance. Disturbed beta-cell function is the final culprit that leads to the development of T2D. In addition, impaired incretin effect is likely a part of the pathogenesis of T2D. The aim of this thesis was to study

https://www.ludc.lu.se/education-training/theses/theses-2017/role-cocaine-and-amphetamine-regulated-transcript-endocrine-cells - 2025-08-19

Rickard Claesson

Gestational Diabetes Mellitus - Diagnostic Implications during Pregnancy and follow-up The overall objective of the present thesis was to assess diagnostic implications for diagnosis of gestational diabetes (GDM) during pregnancy (Papers I and V) and for diagnosis of type 2 diabetes at follow-up after pregnancy (Papers II and IV), and the relative contriubtions of maternal body mass index (BMI) an

https://www.ludc.lu.se/education-training/theses/theses-2017/gestational-diabetes-mellitus-diagnostic-implications-during-pregnancy-and-follow - 2025-08-19

Botnia

The Botnia study The Botnia study was initiated in 1990 on the western coast of Finland in the Gulf of Bothnia with the aim to:Characterize the early metabolic defects in individuals at risk of developing type 2 diabetesIdentify genetic variants predisposing to type 2 diabetesStudy how the identified genetic markers and biomarkers can predict the development of type 2 diabetes and progression of t

https://www.ludc.lu.se/resources/cohorts/botnia-0 - 2025-08-19

Genomics

The genetic spectrum of diabetesAn important aim of this Initiative is to provide a gene atlas of T2D. Together with co-workers at the Broad Institute (MIT/Harvard) and Novartis we will perform a SNP genome wide association study using 500,000 SNPs on an Affymetrix chip in 1500 Scandinavian patients with T2D and 1500 non-diabetic control subjects. We expect at least 1500 SNPs (1.5%) to show nomina

https://www.ludc.lu.se/welcome-lund-university-diabetes-centre/project-areas/genomics - 2025-08-19

Confocal Platform

Link to user agreement and fees confocal platform (pdf file in English) Link to user agreement and fees confocal platform (pdf file in Swedish) user_instructions_must_read.pdf lsm_800_confocal_power_pack.pdf en_wp_airyscan-detector.pdf service_descriptions_premium.pdf Related information Mouse rettinal microvessels optical_sectioning_techniques_zeiss_training_slides.pdf - presentation by Dr. Sebas

https://www.ludc.lu.se/resources/confocal-platform - 2025-08-19

Inflammation

Metabolic and inflammatory pathwaysCross-talk between metabolic and inflammatory pathways contributes to the pathology in many, if not most, forms of diabetes and its complications. In humans it is not possible to extract mechanistic information on how inherited defects in autoimmune/ inflammatory and metabolic pathways interact to cause damage to β-cells and target cells, culminating in diabetes.

https://www.ludc.lu.se/welcome-lund-university-diabetes-centre/project-areas/inflammation - 2025-08-19

LUPOP at Medicon Village

Presentation of LUPOP on April 5, 2018 Here you will find links from the presentation of LUPOP at Medicon Village on April 5, as well as the actual presentation. LUPOP on facebook: https://www.facebook.com/LUPOPplatform  Register Utilisation Tool (RUT): https://www.registerforskning.se/stod-till-dig-som-forskar/rut/ Swedish National Data Service (SND): https://snd.gu.se/en Yammer groups for LU: ht

https://www.lupop.lu.se/lupop-researchers/documents-and-links/presentations-lupop/lupop-medicon-village - 2025-08-19

Anmälan till nationell arbetsgrupp Vintergatan

Namn (required) E-post (required) Tillhörighet / organisation Profession / titel Jag förstår att min information kommer att sparas elektroniskt vid Lunds universitet (required) Ja Leave this field blank Workshop Online workshop om verksamhetsarkitektur och forskningsdata  Vintergatan Vintergatan - ett verktyg för att skapa din verksamhetskarta Kontakt Emma-Lisa Hansson (emma-lisa [dot] hansson [at

https://www.lupop.lu.se/form/anmalan-till-nationell-arbetsgrupp-vintergatan - 2025-08-19

Thomas Reinbothe

New aspects of voltage-gated calcium channel regulation in pancreatic beta-cells. Relevance for insulin release and type 2 diabetes Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose low

https://www.ludc.lu.se/education-training/theses/theses-2011/thomas-reinbothe - 2025-08-19