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Phenotypic modulation of smooth muscle is associated with various pathological conditions, including bladder dysfunction. Cytoskeletal dynamics modulate the cell phenotype and were recently shown to be involved in regulation of inducible nitric oxide synthase ( iNOS). We tested the hypothesis that the cell differentiation status affects iNOS expression, and that iNOS is preferentially expressed in
Popular Abstract in Swedish I den här doktorsavhandlingen presenteras ett datorprogram som utvecklats för att simulera och utvärdera biotekniska processer, där flera processteg kan vara integrerade. Speciellt har en process för framställning av mjölksyra från vetemjöl studerats. Mjölksyra har traditionellt använts i kemi-, läkemedels- och livsmedelsindustrin som t.ex. råvara, surgörare eller konseBiotechnical processes are often integrated to increase productivity and yield. It is difficult to predict the effects of process integration and to find optimum conditions for the process. A valuable tool for the evaluation of a complete process is mathematical modelling. In this thesis, a computer program developed for simulation and optimisation of integrated biotechnical processes is presented
The effect on haemostatic variables by dextran 70, enoxaparin and their combinations, given in doses of 500 ml i.v. and 40 mg s.c. respectively, was studied in a randomised cross-over fashion in twelve healthy male volunteers. Antifactor-IIa activity, antifactor-Xa activity, APTT, factor VIII, vWF, bleeding time and blood counts were analysed over a 24-h period. Dextran alone did not affect antifa
The crystal structures of Bi2.5Na0.5Ta2O9 and Bi2.5Nam-1.5NbmO3m+3 (m = 3,4) have been investigated.ysis of their neutron powder diffraction by the Rietveld anal patterns (lambda = 1.470 Angstrom). These compounds belong to the Aurivillius phase family and are built up by (Bi2O2)(2+) fluorite layers and (A(m-1)BnO(3m+1))(2-) (m = 2-4) pseudo-perovskite slabs. Bi2.5Na0.5Ta2O9 (m = 2) and Bi2.5Na2.5
A natural treatment system for the treatment of leachate was Studied at Moskogen landfill in southern Sweden. This facility consists of three consecutive ponds and a soil-plant (SP)system. A test area, receiving water from the third pond with the same hydraulic load as the SP-systern, was Used for estimation of the latter system. Quality parameters including biochemical oxygen demand, total organi
A time-related deterioration in male reproductive function caused by exposure to endocrine disrupters, including persistent organochlorines (POCs), has been hypothesized. In animal studies, POCs were found to have adverse effects on male reproductive function. However, little is known about the impact of POC exposure on reproductive parameters in men. In a study of 305 young Swedish men 18-21 year
PURPOSE. Cystatin C is a mammalian cysteine protease inhibitor, synthesized in various amounts by many kinds of cells and appearing in most body fluids. There are reports that it may be synthesized in the mammalian retina and that a cysteine protease inhibitor may influence the degradation of photoreceptor outer segment proteins. In the current study cystatin C was identified, quantitated, and loc
Patients with a previous history of anaphylactic reactions to ionic iodinated contrast media were desensitised before a second radiologic examination was performed. The tolerance to the contrast medium was raised by repeated intravenous injections in increasing doses and concentrations. No serious side effects were noted when the examinations with contrast medium was repeated within a few days aft
Extracts of the seeds of Aframomum sulcatum (Oliv. & Hanb) K. Schum (Zingiberaceae) yielded a novel norbislabdane derivative, sulcanal (1) and the new labdane (12E)-8beta,17-epoxy-11-hydroxy-12-labden-15.16-dial-11,15-hemiacetal (2) (as a 1:1 C-15 epimeric mixture), along with known labdane diterpenes.
Popular Abstract in Swedish Organiskt avfall utgör ett problem men är samtidigt en resurs med dess innehåll av näringsämnen och energi. Ett sätt att ta om hand organiskt avfall är att bryta ned det anaerobt genom s.k. rötning. Det organiska materialet reduceras då samtidigt som biogas produceras. Biogas består till största delen av metan som är energirikt och kan ersätta fossila bränslen vid prodAnaerobic digestion of organic matter results in the production of biogas, which can be used to replace fossil fuels. There is potential for increased biogas production at wastewater treatment plants by digesting urban organic waste either separately or together with the sludge. Biogas production could also be increased by sludge pre-treatment. The objective of this work was to evaluate the poten
This study compared the methods of determining the footwear insulation on human subjects and the thermal foot model. Another purpose was to find out minimal number of measurement points on human foot that is needed for insulation calculation. Bare foot was tested at three ambient temperatures on 6 subjects. Three types of footwear were tested on 2 subjects. The mean insulation for bare foot obtain
In dentistry, allergic contact dermatitis to acrylates and allergic contact urticaria to latex are important occupational hazards. There is a need to identify non-latex gloves which are suitable for dental work but at the same time provide adequate protection against acrylate monomers. In a previous study, a new open-chamber system was used for testing the in vivo protection of 6 different gloves
The cone snail is the only invertebrate system in which the vitamin K-dependent carboxylase (or gamma-carboxylase) and its product gamma-carboxyglutamic acid (Gla) have been identified. It remains the sole source of structural information of invertebrate gamma-carboxylase substrates. Four novel Gla-containing peptides were purified from the venom of Conus textile and characterized using biochemica
The 28-kd plasma protein alpha(1)-microglobulin is found in the blood of mammals and fish in a free, monomeric form and as high-molecular-weight complexes with molecular masses above 200 kd. In this study, iodine 125-labeled free and high-molecular weight rat alpha(1)-microglobulin (a mixture of alpha(1)-microglobulin/alpha(1)-inhibitor-3 and alpha(1)-microglobulin/fibronectin complexes) were inje
