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We propose a simple approach to treatment effect estimation in panel data that is valid when the number of time periods is small and the parallel trends condition is violated due to the presence of interactive fixed effects. The procedure allows the covariates to be affected by treatment and enables separation of the part of the estimated treatment effect that is due to the covariates from the par

Researchers use area of interest (AOI) analyses to interpret eye-tracking data. This article addresses four key aspects of AOI use: 1) how to report AOIs to support replicable analyses, 2) how to interpret AOI-related statistics, 3) methods for generating both static and dynamic AOIs, and 4) recent developments and future directions in AOI use. The article underscores the importance of aligning AO

Inflammation and infection remain unmet challenges in wounds of various etiologies, delaying healing, impacting quality of life, and increasing healthcare costs. The thrombin-derived C-terminal peptide TCP-25 has demonstrated dual anti-inflammatory and antibacterial activities in animal wound infection models, thereby promoting healing, highlighting its therapeutic potential as a wound treatment.

China plans expanding 49.5 million hectares of new forests by 2050 to strengthen carbon sequestration. However, estimates of the carbon benefits from this expansion rarely consider the effect of 'forest edge', where tree mortality increases under intensified stress from wind, drought, pests, and fire. Here we show that proximity to forest edges substantially reduces biomass carbon storage, and dev

Increasing drought frequency and intensity affect biophysical functions of natural ecosystems. In tropical semi-arid savannas, while immediate drought effects are well-studied, the drought legacy effects on vegetation composition and associated ecosystem functions remain unclear. We used data of vegetation composition, net ecosystem CO 2 exchange, surface albedo and evapotranspiration (ET) in 201

Over-reliance in high-risk industries on prescriptive emergency procedures and the capacity of high-fidelity simulation has initiated the search for new steps for training for unexpected and escalating situations. This chapter outlines a theoretical framework describing the adaptive and flexible competencies that add up to an organisation’s resilience in escalating situations. To make the framewor

Background: SARS-CoV-2 remains globally circulating, yet post-pandemic comprehensive molecular, serological, and population-level immunity data from low-resource settings such as Ethiopia are limited. This study employed genomic surveillance with seroepidemiological assessment to characterize the epidemiology of SARS-CoV-2 among individuals presenting with influenza-like illness (ILI) and severe a

Background: Diffuse large B-cell lymphoma (DLBCL) exhibits immunological heterogeneity that influences outcomes of immunochemotherapy, with CD8+ T cells playing a critical role in patient prognosis. Methods: We integrated single-cell and bulk transcriptome data to establish a CD8⁺ T cell–associated prognostic signature. Single-cell RNA sequencing data from 29 samples (28 individuals), including DL

OBJECTIVE: To describe the distribution of HIV-1 variants in population-based national surveys conducted in sub-Saharan African countries between 2015 and 2022.DESIGN: Multicountry analysis.METHODS: Sixteen population-based national surveys, conducted between 2015 and 2022, were analyzed. Survey participants were eligible if HIV genotyping was successful. In most countries, people with HIV (PWH) w

Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of part

How can different value chain actors mitigate threats or benefit from moments of volatility? This question has become essential as global value chains are restructuring, with policymakers and management scholars calling for increasing value chain resilience. Surveying geographers’ recent contributions, this paper develops a geographical political economy of value chain resilience, which helps expl

Much of the hype about AI exploits the fact that human cognition, language, and categorization rely on imaginative scaffolding. Some degree of metaphor and conceptual borrowing should not be seen as a methodological failure. Law does not meet AI as a blank slate. It reaches for metaphors and other imaginative patterns that make the unfamiliar legible, channeling attention toward certain features a

Immune thrombocytopenia (ITP) is characterized by the overproduction of antiplatelet autoantibodies. Although B-cell depletion therapies show promise in ITP, their high relapse rates suggest a potential de novo breakdown of tolerance during an early stage of B-cell development. Here, we investigated how central B-cell tolerance mechanisms affect autoantibody production in ITP. Paired single-cell R

Weight stigma is a social justice issue that can lead to weight-based discrimination and mistreatment. In pregnancy, emerging evidence has highlighted that weight stigma predominantly affects individuals who have larger bodies and is associated with postpartum depression and avoidance of healthcare. Racial and ethnic background will influence perceptions of, and responses to, weight stigma and the