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Silver-Coated Ventriculostomy Catheters Do Not Reduce Rates of Clinically Diagnosed Ventriculitis

Background: Ventriculitis is a serious complication when using external ventricular drains (EVDs). Bactericidal silver coating has been reported to reduce risk of infection. In the clinical setting, the diagnosis is often made based on symptoms and analyses of cerebrospinal fluid, with treatment initiated before infection is verified by culture. The bactericidal effect might not correlate with a r

Cerebrospinal fluid neurofilament light is associated with survival in mitochondrial disease patients

We studied the biomarker patterns related to axonal injury, astrogliosis and amyloid metabolism in cerebrospinal fluid (CSF) of children and adolescents with mitochondrial encephalopathy and identified correlations with phenotype and survival outcome. Forty-six pediatric patients with genetically verified mitochondrial encephalopathy and twenty-two controls investigated at the Queen Silvia Childre

The Housing Enabler instrument : Assessing threats to reliability and validity

Introduction: The Housing Enabler instrument, designed to measure housing accessibility, has not been used in samples with long-standing spinal cord injury. We aimed to investigate potential threats to the reliability and validity of the instrument when used among older adults with spinal cord injury. Method: Cross-sectional data from the Swedish Aging with Spinal Cord Injury Study (N = 123, injur

Construction and assessment of reduced oxidation mechanisms using global sensitivity analysis and uncertainty analysis

The global sensitivity analysis is an effective method to assess the performance of a chemical reaction mechanism. In the present study, the uncertainty analysis and the global sensitivity analysis of a detailed chemical mechanism of n-heptane are first performed based on the Monte Carlo method. The source of the prediction uncertainties of the C0-C7 sub-mechanisms and the reaction classes in the

Over-determined Harms and Harmless Pluralities

A popular strategy for meeting over-determination and pre-emption challenges to the comparative counterfactual conception of harm is Derek Parfit’s suggestion, more recently defended by Neil Feit, that a plurality of events harms A if and only if that plurality is the smallest plurality of events such that, if none of them had occurred, A would have been better off. This analysis of ‘harm’ rests o

Nathan Söderblom and «nationalism» : Riga, Uppsala, and the Ruhr

Due to his ecumenical internationalism, the Swedish Archbishop Nathan Söderblom has been regarded as an opponent of nationalism, contrary to some other Swedish theologians of his time. However, as has been demonstrated by Kjell Blückert, Aila Lauha and others, Söderblom was not without nationalist tendencies. Other scholars have tried to explain his nationalism as mere patriotism. By closely exami

Search for heavy resonances decaying into a W or Z boson and a Higgs boson in final states with leptons and b-jets in 36 fb−1 of √s=13 TeV pp collisions with the ATLAS detector

A search is conducted for new resonances decaying into a W or Z boson and a 125 GeV Higgs boson in the νν¯ bb¯ , ℓ±νbb¯ , and ℓ+ℓ−bb¯ final states, where ℓ± = e± or μ±, in pp collisions at s=13 TeV. The data used correspond to a total integrated luminosity of 36.1 fb−1 collected with the ATLAS detector at the Large Hadron Collider during the 2015 and 2016 data-taking periods. The search is conduct

Enhancement of loop heat pipe performance with the application of micro/nano hybrid structures

To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel

Ignition processes and modes excited by laser-induced plasma in a cavity-based supersonic combustor

The ignition processes in an ethylene-fueled supersonic combustor excited by laser-induced plasma (LIP) were investigated experimentally under the condition of inflow Ma number of 2.92. The LIP excitation was implemented near the center floor of a flameholding cavity. Optical measurements, including simultaneous CH∗/OH∗ chemiluminescence imaging and Schlieren photography, were used to investigate

Effects of a gestational weight gain restriction program for obese women : Sibling pairs’ weight development during the first five years of life

Objectives: Successful gestational weight gain (GWG) restriction programs for obese (Body Mass Index (BMI) ≥ 30 kg/m2) pregnant women, have not, so far, shown convincing effects on infant's weight development. An intervention starting during the pregnancy might be too late and a pre-conceptional life style change may be preferable. Thus, the aim of this study was to follow children born to mothers

Factorizations induced by complete Nevanlinna–Pick factors

We prove a factorization theorem for reproducing kernel Hilbert spaces whose kernel has a normalized complete Nevanlinna–Pick factor. This result relates the functions in the original space to pointwise multipliers determined by the Nevanlinna–Pick kernel and has a number of interesting applications. For example, for a large class of spaces including Dirichlet and Drury–Arveson spaces, we construc