Filtyp
Abstract Heart failure is a common and disabling disease with high mortality that carries substantial societal costs. Current therapeutic strategies are aimed at relieving symptoms, avoiding hospitalization, and prolonging life, but disease progression is ultimately inevitable. MicroRNAs (miRNAs) are short, non-coding RNA molecules with pervasive roles in eukaryotic biology, annealing to complimen
Global maritime security has been a subject of analysis and debate in the West since the onset of the European expansion. This article distinguishes four main periods with regard to the doctrines and practices of global maritime security since c. 1450, during which the role of the state in relation to private actors has shifted. As a concept of global policy making, however, maritime security only
Transvaginal ultrasound plays a pivotal role in the management of non-pregnant women with abnormal vaginal bleeding. No other imaging technique has a role in the triage of these women. In women with postmenopausal bleeding, ultrasound is used to categorise women as at low or high risk of endometrial cancer, and the result of the ultrasound examination is the basis for further management. In women
Brain injury affects neurologic function and quality of life in survivors after cardiac arrest.
The test of Ng (A simple test for nonstationarity in mixed panels, Journal of Business & Economic Statistics 26, 113–126, 2008) is one of the few that enables general inference regarding the proportion of non-stationary units in panel data. The current paper furthers the investigation of Ng (2008) in two directions. First, the existing sequential limit analysis is generalized to a very flexibl
High-elevation grasslands of the Cyperaceae Kobresia pygmaea cover nearly half a million km2 on the Tibetan Plateau. As a consequence of climate change, precipitation patterns in this monsooninfluenced region may change with possible consequences for grassland productivity. Yet, not much is known about the water cycle in this second largest alpine ecosystem of the world. We measured the evapotrans
The aim of this article is to examine how the Swedish Sports Organization for the Disabled (SHIF) portrays disabled people. A text analysis of two policy documents, 'Disability Sports Policy Programme' and 'Sports Objectives - A Summary of Aims and Guidelines for the Sports Movement', examines ways in which sports are supposed to affect people's bodies and contribute to society. Counter to its own
The properties of dipolar cubic lattices are studied and the paradox of how to obtain a long range polarization in such lattices is resolved by choosing a proper shape of the total system. It has been shown that large but finite number of aligned dipoles prefer to exist as needle shaped macroscopic particles [M. Yoon and D. Tománek, J. Phys.: Condens. Matter 22, 455105 (2010)]. The total energy fo
We use a recently developed continuum theory to expand on an exact treatment of the interfacial properties of telechelic polymers displaying Schulz-Flory polydispersity. Our results are remarkably compact and can be derived from the properties of equilibrium, ideal polymers at interfaces. A new surface adsorption transition is identified for ideal telechelic chains, wherein the central block is an
A numerical model of undertow due to random waves is developed. The model includes three sub-models: (i) a model for multi-directional and multi-frequency random wave transformation, (ii) a surface roller evolution model, and (iii) a model for calculating the vertical distribution and the mean value of the undertow velocity. The calculation of wave trough level is performed based on a theory for t
The aim of this study is to investigate the feasibility of using three-directional velocity encoded 3D gradient echo (GE) phase contrast (PC) imaging to assess cerebrospinal fluid (CSF) flow connectivity in the human brain. Five healthy volunteers were scanned using low velocity sensitivity (V-enc = 0.04-0.05 m s(-1)). Flow-time curves were compared to standard 2D PC scans. The 3D data were used t
The role of structural genetic changes in human disease has received substantial attention in recent decades, but surprisingly little is known about numerical chromosomal abnormalities, even though they have been recognized since the days of Boveri as partaking in different cellular pathophysiological processes such as cancer and genomic disorders. The current knowledge of the genetic and epigenet
Objective: The most widely studied positron emission tomography ligand for in vivo P-amyloid imaging is C-11-Pittsburgh compound B (C-11-PIB). Its availability, however, is limited by the need for an on-site cyclotron. Validation of the F-18-labeled PIB derivative F-18-flutemetamol could significantly enhance access to this novel technology. Methods: Twenty-seven patients with early-stage clinical
The phenomenon of contact guidance on thin fibers has been known since the beginning of the 20th century when Harrison studied cells growing on fibers from spider's web. Since then many studies have been performed on structured surfaces and fibers. Here we present a new way to induce guidance of cells or cell processes using magnetic nanowires. We have manufactured magnetic Ni-nanowires (200 nm in
In this study, the relation between fruit and vegetable consumption and mortality was investigated within the European Prospective Investigation Into Cancer and Nutrition. Survival analyses were performed, including 451,151 participants from 10 European countries, recruited between 1992 and 2000 and followed until 2010. Hazard ratios, rate advancement periods, and preventable proportions to respec
There are various ways to classify asthma control; however, no classification is universally accepted. This retrospective analysis compared asthma control as assessed by the Asthma Control Questionnaire (5-item version; ACQ-5), Global Initiative for Asthma (GINA) or Gaining Optimal Asthma Control (GOAL) study criteria. Pooled data at the final study week (n=8,188) from three budesonide/formoterol
We have studied nucleation and crystal growth of calcium carbonate on hard surfaces, i.e. stainless steel and silica, at different temperatures, in relation to the corresponding bulk processes, using scanning electron microscopy (SEM), X-ray diffraction (XRD), and ellipsometry. In the bulk solution, a mixture of all three calcium carbonate crystalline polymorphs, calcite, aragonite, and vaterite,
This paper introduces a two-dimensional extension of the well established Rietveld refinement method for modeling neutron time-of-flight powder diffraction data. The novel approach takes into account the variation of two parameters, diffraction angle 2θ and wavelength λ, to optimally adapt to the varying resolution function in diffraction experiments. By doing so, the refinement against angular- a
