Various approaches to flame-spread and fire-growth modelling are discussed and are evaluated using experimental results from different tests. Use of Computational Fluid Dynamics, CFD, in fire modelling is discussed and the performance of different CFD codes in wall flow modelling is analysed. Different pyrolysis models are discussed with respect to their major assumptions and the input data requir

Inactivation of the Ink4 gene locus locus on 9p comprising the tumour suppressor gene p16ink4a and its neighbours p14ARF and p15ink4b is common in childhood acute lymphoblastic leukaemia (ALL), but the prognostic significance is controversial. DNA from 230 patients was retrospectively analysed by Southern blotting, single strand conformation polymorphism (SSCP) and sequencing techniques. The resul

Forty-one names of species and varieties of Hieracium sect. Hieracium, H. sect. Vulgata and H. sect. Bifida originally described from the province of Värmland, western central Sweden, are lectotypified.

In recent years, the growing scientific interest in design has led to great advances in our knowledge of authentic design processes. However, as these findings go counter to the existing theories in both design research and cognitive science, they pose a serious challenge for both disciplines: there is a wide gap between what the existing theories predict and what designers actually do. At the sa

The aim of this study is to investigate whether current statistics can quantify the benefits of fire brigades. A detailed investigation by the London Fire Brigade of most fires in the greater London area has been underway since 1994. The present study concerns 307 fires in non-residential buildings between 1994 and 1997. Times to detection, to arrival of the fire brigade, and to extinguishment of

Chicken cooked under well-controlled conditions and commercial chicken products were screened for heterocyclic amines (HAs). Chicken samples were boiled, deep-fried, pan-fried, oven-roasted, cooked in an unglazed clay pot or in a roasting bag in the oven, and oven broiled. 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (4,8-DiMeIQx), 2-amino

Bone mineral density (BMD) was measured in the upper part of the skull, the femoral neck, and the total body by dual energy X-ray absorptiometry in 56 male and 33 female active athletes, 18-40 years of age, together with 64 male ex-weight lifters, 35-79 years of age. The active athletes were compared with 41 male and 54 female controls, the ex-weight lifters with 133 male controls. The purpose of

Background. To characterize history, signs, and symptoms in women with a history of recurrent vulvovaginal candidosis (RVVC) and who had consulted with symptoms generally associated with the condition. Methods. Eighty-three women with a history consistent with RVVC were interviewed regarding 32 parameters and 10 signs found at the clinical examination were noted. Candida cultures were made from t

Gas6 and protein S are two homologous secreted proteins that depend on vitamin K for their execution of a range of biological functions. A discrete subset of these functions is mediated through their binding to and activation of the receptor tyrosine kinases Axl, Sky and Mer. Furthermore, a hallmark of the Gas6-Axl system is the unique ability of Gas6 and protein S to tether their non receptor-bin

PURPOSE. To study the possible involvement of the rod (SLC24A1) and cone (SLC24A2) Na-Ca+K exchanger (NCKX) genes in retinal diseases. METHODS. DNA was collected from unrelated patients with retinal disease, mainly from North America. A human genomic library was screened with the cone NCKX cDNA, and hybridizing clones were sequenced to determine the genomic organization of the SLC24A2 gene. The si

Endothelins are recently discovered peptides that cause vasoconstriction and bronchoconstriction. The significance to the mucociliary system of endothelins (ET) 1, 2 and 3 in upper as well as lower airways has not yet been clarified. Effects of these active peptides were investigated, combining both in vitro and in vivo rabbit models of mucociliary activity from the maxillary sinus and the trachea

The stochastic behavior of FM-clicks in an unmodulated carrier plus noise is studied in terms of the conditional behavior of stationary Gaussian processes after level crossings. By a systematic use of thc Slepian model processes it is shown that the normalized shape of a positive FM-click approaches a certain rational function with simple random coefficients as the carrier-to-noise ratio tends to

This paper presents a method to relax Dynamic Programming. The methodmakes it possible to findsuboptimal solutions with known error bounds to hard problems.The bounds are chosen by the user, who can then effectively trade-offbetween solution time and accuracy. Several examples from differentdomains where the method is highly useful are presented.

We recently identified a candidate tumor suppressor gene, HIN-1, that is silenced due to methylation in the majority of sporadic breast carcinomas and is localized to 5q33-qter, an area frequently lost in BRCA1 tumors and thought to harbor a BRCA1 modifier gene. To establish whether germ-line mutations in HIN-1 may influence breast cancer risk, we sequenced the HIN-1 coding region in 10 familial b