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On the trail of Vikings with polarized skylight: experimental study of the atmospheric optical prerequisites allowing polarimetric navigation by Viking seafarers

Between AD 900 and AD 1200 Vikings, being able to navigate skillfully across the open sea, were the dominant seafarers of the North Atlantic. When the Sun was shining, geographical north could be determined with a special sundial. However, how the Vikings could have navigated in cloudy or foggy situations, when the Sun's disc was unusable, is still not fully known. A hypothesis was formulated in 1

Optimal bird migration revisited

Using optimality perspectives is now regarded as an essential way of analysing and understanding adaptations and behavioural strategies in bird migration. Optimization analyses in bird migration research have diversified greatly during the two recent decades with respect to methods used as well as to topics addressed. Methods range from simple analytical and geometric models to more complex modeli

Knowledge-Based Industrial Robotics

When robots are working in dynamic environments, close to humans lacking extensive knowledge of robotics, there is a strong need to simplify the user interaction and make the system execute as autonomously as possible. For industrial robots working side-by-side with humans in manufacturing industry, AI systems are necessary to lower the demand on programming time and expertise. We are convinced th

Review of highly charged tungsten spectroscopy research using low energy EBITs at the Shanghai EBIT laboratory

We present an overview of recent work on the spectroscopy of tungsten ions, related to tokamak edge plasma. The spectra were recorded from the newly-built low energy electron beam ion traps (EBITs) in the Shanghai EBIT laboratory. By analyzing the spectra with the help of accurate theoretical calculations, using state-of-the-art techniques, we were able to identify term and fine structure splittin

Expanded clinical and experimental use of SOX11-using a monoclonal antibody

Background: The transcription factor SOX11 is of diagnostic and prognostic importance in mantle cell lymphoma (MCL) and epithelial ovarian cancer (EOC), respectively. Thus, there is an unmet clinical and experimental need for SOX11-targeting assays with low background, high specificity and robust performance in multiple applications, including immunohistochemistry (IHC-P) and flow cytometry, which

Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA

The thiol-disulfide oxidoreductase ResA from Bacillus subtilis fulfils a reductive role in cytochrome c maturation. The pK(a) values for the CEPC (one-letter code) active-site cysteine residues of Ill are unusual for thioredoxin-like proteins ill that they are both high (> 8) and within 0.5 unit of each other. To determine the contribution of the inter-cysteine dipeptide of ResA to its redox and a

Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Non trauma Surgical Patients

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are commonly encountered in nontrauma surgical patients. Depending on the etiology of the patient's surgical illness (ruptured abdominal aortic aneurysm, acute pancreatitis, burns, etc.), both the incidence and mortality of IAH/ACS may be quite high. Recent advances in both the diagnosis and resuscitation of these surgical

Selective determination of acidic pharmaceuticals in wastewater using molecularly imprinted solid-phase extraction.

The determination of acidic pharmaceuticals, such as non-steroidal anti-inflammatory drugs NSAIDs and clofibric acid (metabolite of clofibrate), at low ngL(-1) levels in wastewater requires highly selective and sensitive analytical procedures. The removal of matrix components during sample preparation results in significant benefits towards reducing the matrix effects during LC-MS analysis. Theref

Controllable p-doping of graphene on Ir(111) by chlorination with FeCl(3).

The in situ chlorination of graphene on Ir(111) has been achieved by depositing FeCl(3) followed by its thermal decomposition on the surface into FeCl(2) and Cl. This process is accompanied by an intercalation of Cl under graphene and formation of an epitaxial FeCl(2) film on top, which can be removed upon further annealing. A pronounced hole doping of graphene has been observed as a consequence o

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

Gestational diabetes mellitus is associated with TCF7L2 gene polymorphisms independent of HLA-DQB1*0602 genotypes and islet cell autoantibodies.

Aims: To test whether the TCF7L2 gene was associated with gestational diabetes, whether the association between TCF7L2 and gestational diabetes was independent of HLA-DQB1*0602 and islet cell autoantibodies, as well as maternal age, number of pregnancies, family history of diabetes and the HLA-DQB1 genotypes, and to test whether the distribution of HLA-DQB1 alleles was affected by country of birth

A river ran through it: post-conflict peacebuilding on the Sava River in former Yugoslavia

The Sava River flows through Slovenia, Croatia, Bosnia-Herzegovina and Serbia on its way to join the Danube at Belgrade. This formerly national river became an international one as a result of the break-up of Yugoslavia due to the 1991-95 Yugoslav Wars. Following an overview of the conflict and a description of the Sava River Basin, this article describes the post-conflict challenges to joint mana

Millennial Climatic Fluctuations Are Key to the Structure of Last Glacial Ecosystems

Whereas fossil evidence indicates extensive treeless vegetation and diverse grazing megafauna in Europe and northern Asia during the last glacial, experiments combining vegetation models and climate models have to-date simulated widespread persistence of trees. Resolving this conflict is key to understanding both last glacial ecosystems and extinction of most of the mega-herbivores. Using a dynami

Comparison of horizontal and vertical advective CO2 fluxes at three forest sites

Extensive field measurements have been performed at three CarboEurope-Integrated Project forest sites with different topography (Renon/Ritten, Italian Alps, Italy; Wetzstein, Thuringia, Germany; Norunda, Uppland, Sweden) to evaluate the relevant terms of the carbon balance by measuring CO2 concentrations [CO2] and the wind field in a 3D multi-tower cube setup. The same experimental setup (geometry

The Negotiation of Collective Identities in German Cinema after Unification

This article analyses the negotiation of German identities in two films of the ‘newer German cinema’: Sonnenallee/Sun Alley (Haussmann 1999) and Schultze gets the blues (Schorr 2003). It argues that the former represents a defiant stance towards a dominant West German narrative which devalorizes the lived experiences of former GDR citizens. As a consequence, east and west are consolidated as relev

Tolerance and Immunity: Opposite Outcomes of Microbial Antigen Stimulation

The immune system is remarkable in many ways. It exerts immunity to defend us from foreign pathogens, while it is also responsible for maintaining tolerance to avoid autoimmune diseases and allergy. This thesis includes three separate papers concerning both tolerance and immunity. In paper I we report that repeated antigen stimulation results in an increased proportion of Foxp3+ cells in the CD4+

A step-wise method for annotating APPRAISAL

Despite a growing awareness of methodological issues, the literature on APPRAISAL has not so far provided adequate answers to some of the key challenges involved in reliably identifying and classifying evaluative language expressions. This article presents a step-wise method for the manual annotation of APPRAISAL in text that is designed to optimize reliability, replicability and transparency. The