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Patients with pulmonary arterial hypertension (PAH) experience long diagnostic delays, high functional class at diagnosis and poor prognosis. We aimed to study the differentiative and predictive value of 90 inflammatory and immunomodulatory related proteins in idiopathic and hereditary PAH (IPAH/HPAH) and systemic sclerosis-associated PAH (SSc-APAH). Cohort 1 comprised patients with SSc-APAH ( n
En syntesmässig sammanfattning av de europeiska ostindiska kompaniernas historia, med störst fokus på Nederländerna och England.
Detta är en finsk översättning av min bok Vikingarnas historia. Översättare: Tiina Sjelvgren.
In everyday listening, speech perception occurs under conditions where acoustic information may be incomplete or ambiguous, including background noise and variability in signal quality. Listeners must navigate ambiguous, masked or rapidly unfolding speech signal in order to comprehend spoken language. While prediction has been widely discussed and acknowledged in speech perception, less is known a
Iran’s extraterritorial violence constitutes a structural element of state policy, implemented through a coordinated system of intelligence services, diplomatic platforms, proxy militias, and criminal intermediaries. Rooted in revolutionary doctrine and operationalized by institutions such as the Islamic Revolutionary Guard Corps (IRGC) and its external arm, the Quds Force, this apparatus has enab
Much foundational work in Sociology of Law (SoL) has considered the role of law in society as well as the role of society in law. This duality has opened for nuanced accounts of the impact of formal law (referred as legal norms herein) by empirically studying formal laws and everyday interactions making up various social norms which may at times align with one another or be in conflict. Recently,
Project Psyche is a transnational initiative to generate and study chromosome-level reference genomes of all ~11 000 species of Lepidoptera (butterflies and moths) found in Europe. Here, we describe the decentralised network of collection and sequencing hubs that has enabled rapid progress, the standardised protocols for sampling and sequencing, and the collaborative framework for data analysis. W
Outbreaks of highly pathogenic avian influenza (HPAI) pose an escalating threat to global poultry supply chains, with their management highlighting reconfigurations in economic geography through the increasing centrality of actors and processes beyond the farm-level. Taking HPAI outbreaks in Denmark as our empirical focus, we argue that outbreaks and their management reveal poultry growers’ lack o
Background: Alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) are frequently comorbid and are individually associated with increased risk of suicidal behavior. However, whether their comorbidity exacerbates this risk has not been adequately investigated. Methods: Using a Swedish birth cohort (born 1970–1990; N = 799,203–858,983), we employed Aalen’s linear hazards models to evalu
In three empirical studies, we compare one syntactic and one semantic approach to agreement preferences in so-called pancake constructions (pcs) in Swedish, as in Senap är starkt ‘Mustard is strong’.pcs are either substance-denoting, naming an inherent property of the subject, or situation-denoting, naming a property of the subject that is linked to some event. These two types were found to differ
Conceptualising public authority as continually performed, this paper traces the interplay between modes of legitimation, state capacity and scalar politics in governing the COVID-19 pandemic. Despite attempts to unify COVID responses nationally, governance practices differed across India’s cities: Ahmedabad (Gujarat) heightened policing, Thiruvananthapuram (Kerala) engaged its decentralised gover
This is a scoping review of low-intensity, home-based interventions promoting learning for 11–17-year-olds in foster care. Research shows that children in out-of-home care fall behind in school compared to their peers. Interventions to improve learning outcomes for these children typically i) target young children or children aging out of care, and ii) require many resources to implement. Lo
Background: Laparoscopic cholecystectomy (LC) is performed by surgeons from various specialties and remains central to minimally invasive surgical training. This study assessed whether surgeon subspecialty affects patient outcomes and explored aspects of LC education. Methods: This population-based study included 46,700 LCs performed between 2020 and 2023, using data from the Swedish Registry for
IntroductionSport-related concussion (SRC) is one of the most common and concerning injuries in team sports, with potential long-term effects on athlete health and performance. Linear head acceleration (LHA) and rotational head acceleration (RHA) are central biomechanical markers of brain loading during impact. Yet, the magnitude of these accelerations during SRC events remains poorly synthesized
