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HbA1c Levels Do Not Affect Long-Term Outcome After Open Trigger Finger Release in Individuals With Diabetes Mellitus

BACKGROUND: Trigger finger surgery typically has a successful outcome, also in patients with diabetes mellitus (DM). However, the impact of glycemic control on long-term outcomes after open trigger finger release (OTFR) remains unclear. This study examines whether high hemoglobin A1c (HbA1c) levels affect patient-reported outcome (PRO) following OTFR in individuals with type 1 diabetes mellitus (T

Diversity in genetic risk of recurrent stroke : a genome-wide association study meta-analysis

INTRODUCTION: Stroke is a leading cause of death and disability worldwide. Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk disparities exist among ancestral groups. Notably, Africans face double the risk and higher fatality rates compared to Europeans. Although genetic studies, particularly GWAS, hold prom

Urethral pharmacological mechanisms incontinence and bladder emptying : An updated review

BACKGROUND: The urethral wall consists of layers of striated muscle, circular and longitudinal smooth muscles, collagen fibers, and a vascular plexus. However, the relative contributions of these components to urethral pressure in humans remain poorly understood. The circular and longitudinal smooth muscle components can develop a spontaneous contractile activity, generating a basal tone. They can

Transition Governance for Sustainable Urban Freight Systems : Exploring Small and Medium-Sized Cities

Urban freight systems play an indispensable role in contemporary cities. By enabling the continuous flow of goods, they support economic activity and contribute to urban prosperity. At the same time, these activities generate substantial negative externalities, including emissions, noise, congestion and increasing pressures on urban space. As freight activities grow, their impacts intensify, under

Search for single-production of vector-like quarks decaying into Wb in the fully hadronic final state in pp collisions at s = 13 TeV with the ATLAS detector

A search for T and Y vector-like quarks produced in proton-proton collisions at a centre-of-mass energy of 13 TeV and decaying into Wb in the fully hadronic final state is presented. The search uses 139 fb−1 of data collected by the ATLAS detector at the LHC from 2015 to 2018. The final state is characterised by a hadronically decaying W boson with large Lorentz boost and a b-tagged jet, which are

Differential cross-section measurements of Higgs boson production in the H → τ+τ− decay channel in pp collisions at s = 13 TeV with the ATLAS detector

Differential measurements of Higgs boson production in the τ-lepton-pair decay channel are presented in the gluon fusion, vector-boson fusion (VBF), VH and tt¯H associated production modes, with particular focus on the VBF production mode. The data used to perform the measurements correspond to 140 fb−1 of proton-proton collisions collected by the ATLAS experiment at the LHC. Two methods are used

Measurement of tt¯ production in association with additional b-jets in the eμ final state in proton–proton collisions at s = 13 TeV with the ATLAS detector

This paper presents measurements of top-antitop quark pair (tt¯) production in association with additional b-jets. The analysis utilises 140 fb−1 of proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. Fiducial cross-sections are extracted in a final state featuring one electron and one muon, with at least three or four b

Uncertainties in Calibration of an Optical Spectrometer for Measuring Isotope Ratios in Methane : ACS Measurement Science Au

The stable isotope ratios of carbon (δ13C(CH4)) and hydrogen (δ2H(CH4)) in methane (CH4) from atmospheric air samples provide a tracer that can help distinguish the relative contribution of emission sources. These can be continuously measured at atmospheric monitoring stations by optical isotope ratio spectrometer (OIRS) instruments, providing data that is complementary to isotope ratio mass spect

Search for boosted low-mass resonances decaying into hadrons produced in association with a photon in pp collisions at s = 13 TeV with the ATLAS detector

Many extensions of the Standard Model, including those with dark matter particles, propose new mediator particles that decay into hadrons. This paper presents a search for such low mass narrow resonances decaying into hadrons using 140 fb−1 of proton-proton collision data recorded with the ATLAS detector at a centre-of-mass energy of 13 TeV. The resonances are searched for in the invariant mass sp

Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries

Background The global prevalence of congenital heart disease (CHD) is increasing. Research on patient-reported outcomes (PROs) predominantly originates from high-income countries, resulting in an incomplete understanding of the true global burden of CHD from the patient perspective. Therefore, we described perceived health, psychological distress and quality of life (QoL) in a large sample of adul

Search for diphoton resonances in the 66 to 110 GeV mass range using pp collisions at √s = 13 TeV with the ATLAS detector

A search is performed for light, spin-0 bosons decaying into two photons in the 66 to 110 GeV mass range, using 140 fb−1 of proton-proton collisions at s = 13 TeV produced by the Large Hadron Collider and collected by the ATLAS detector. Multivariate analysis techniques are used to define event categories that improve the sensitivity to new resonances beyond the Standard Model. A model-independent

Associations between breathlessness and individuals' satisfaction with sexual life : a nationally representative internet survey

INTRODUCTION: Sexual life is important for many people and may be limited by breathlessness. We evaluated associations between breathlessness and individuals' perceived satisfaction with sexual lives and explored mediating factors in this relationship. METHODS: A cross-sectional, online, population-based survey of Australian adults with key demographics (age, sex, rurality, state/territory) reflec

Impact of increasing overweight and obesity on breathlessness : a review

PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo

Making and breaking promises: On the voluntary provision of public goods under cost uncertainty

Breaking promises might be easier if one faces unexpectedly high costs for keeping them. Inspired by the ‘pledge and review’ mechanisms of the Paris Agreement, we investigate the role of cost uncertainty for both initial non-binding pledges and the subsequent voluntary provision of public goods. Without a pledge review process, we find that cost uncertainty not only leads to rather conservative pl

The private solution trap in collective action problems across 34 nations

Collective action problems emerge when individual incentives and group interests are misaligned, as in the case of climate change. Individuals involved in these problems are generally considered to have two options: contribute toward public solutions such as global warming mitigation or free ride. However, many collective action problems today involve a third option of investing in a “private solu

Measurement of the associated production of a top-antitop-quark pair and a Higgs boson decaying into a bb¯ pair in pp collisions at √s=13 TeV using the ATLAS detector at the LHC

This paper reports the measurement of Higgs boson production in association with a tt¯ pair in the H→bb¯ decay channel. The analysis uses 140 fb-1 of 13 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The final states with one or two electrons or muons are employed. An excess of events over the expected background is found with an observed (expected

Cyclin-dependent kinase 10 controls bone formation and is linked to human skeletal health

BACKGROUND/OBJECTIVE: Bone remodeling is a critical process for skeletal health, and its dysregulation can lead to diseases like osteoporosis. While several Cyclin-Dependent Kinases (CDKs) are known to regulate bone metabolism, the function of CDK10 remains uncharacterized in this context. Human mutations in CDK10 cause the Al Kaissi syndrome, which involves severe skeletal defects, suggesting a

Slowing down : Degrowth and the limits to urban mobility

Cities worldwide face immense challenges in transitioning to a sustainable future. While being structurally and politically bound to continuous growth, the striving for a constant increase in production and consumption puts enormous pressure on our planet and its ecosystems. Degrowth has been proposed as a pathway to solving this dilemma. Although scholarly attention to urban degrowth has expanded

CSR som strategi: Hur butiksanställda upplever företagets hållbarhetsarbete

Corporate Social Responsibility (CSR) has become more important for companies in recent years, both as a marketing tool and a way to demonstrate as well as to maintain the organization's social, economical and environmental sustainability. While many organizations talk about sustainability, it is unclear how well this information reaches their frontline employees working in the stores. This th