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With considerable flux in the peace and conflict landscape, scholars, policymakers, practitioners and publics alike are scrambling to understand emerging realities. Moreover, a sometimes slow academic publishing cycle means that much material appearing in academic journals seems already outdated–reporting on a peace and conflict landscape as though we are still in an era of comprehensive peace pro
This review paper provides a literature review of predictive methods and cybersecurity frameworks essential to safeguard Industry 4.0 manufacturing systems against cyber threats. The review focuses on two key areas: the prediction method and the data used for this prediction. These areas are critical for anticipating cyber threats and implementing effective countermeasures. They underscore the nee
The world has encountered numerous global crises, including epidemics, military conflicts, and economic collapse. Innovative digital technologies, such as Industry 4.0 (I4.0), can undoubtedly help improve industries’ operations during critical times. The dairy industry has seen an increment in technological adoption in the last few years. Adopting cutting-edge technologies is regarded as more feas
The PRIMARY score was implemented in Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) version 2 to improve accuracy for the diagnosis of clinically significant prostate cancer using prostate-specific membrane antigen (PSMA) positron emission tomography (PET). We reviewed overall survival (OS) for patients who underwent PSMA PET for initial staging to evaluate the prognostic valu
The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine
The case presents the Itajuru, a complementary municipal currency in the City of Cabo Frío used in the State of Rio de Janeiro, Brazil.The reader gains insight into the political and economic context in which the Brazilian municipal currencies are introduced, as well as the trade-offs of the various options for designing and governing a municipal currency. The case concludes by presenting students
Purpose: Electronic patient-reported outcomes (ePROs) are used postoperatively to detect complications through real-time symptom monitoring. This study examines whether alerts triggered through the “Recovery Tracker” (RT), an ePRO system, predict 30-day re-admission or re-operation after lumpectomy. Methods: We retrospectively reviewed breast cancer patients who underwent lumpectomy at a single in
The genus Lupinus (Fabaceae) represents an exceptional model system for studying evolutionary processes mediated by pollinators and environmental factors. This review synthesizes evidence on phenotypic variability of floral traits, trait selection by biotic and abiotic factors, and the eco-evolutionary implications of these interactions. Pollinators shape floral traits through specialized selectio
Eutrophication, caused by excessive accumulation of key nutrients such as nitrogen and phosphorus in water, is a major environmental problem that significantly affects water quality and aquatic ecosystems. This thesis project aims to evaluate different adsorption-based treatment methods that can effectively reduce the nutrient content of water. Water samples were collected from various water sourc
There has recently been much interest in Gaussian fields on linear networks and, more generally, on compact metric graphs. One proposed strategy for defining such fields on a metric graph Γ is through a covariance function that is isotropic in a metric on the graph. Another is through a fractional-order differential equation Lα/2 (τu) = W on Γ, where L = κ2 − ∇(a∇) for (sufficiently nice) function
Purpose • To investigate if R1 and R2 can reliably be measured using 3D quantitative MRI in an intraoperative setting when paediatric brain tumour surgery is performed. • To determine whether B1+ inhomogeneities affect R1 and R2 measurements in normal-appearing white matter and the thalamus, respectively, and how R1 and R2 measurements are affected by different coils. • To assess how the relaxatio
Regularized models are often sensitive to the scales of the features in the data and it has therefore become standard practice to normalize (center and scale) the features before fitting the model. But there are many different ways to normalize the features and the choice may have dramatic effects on the resulting model. In spite of this, there has so far been no research on this topic. In this pa
Background: Early metastatic spread represents a challenge in fighting small cell lung cancer (SCLC). The molecular mechanisms underlying metastatic dissemination remain unclear in this devastating disease. Methods: Invasive traits were investigated in 13 SCLC cell lines using 3D-spheroid formation, sprouting assays, co-cultures and a zebrafish xenograft model. Proteomic analysis was performed to
European forests have served as a critical carbon sink, absorbing approximately 10% of annual anthropogenic CO₂ emissions in the EU, as a result of both increased forest area and growing stock since 1950. However, this sink has declined by one-third over the past decade, based on the EU National Greenhouse Gas Inventory. This decline has been proposed to be due to multiple interacting factors: cli
Performance featuring spherical amplification.Musikfabrik im WDR 90WDR Funkhaus, Cologne (DE)Ensemble Musikfabrik03/10/2024From the program:Kampe, Gordon (*1976, DE) – Schnulzen (for ensemble) [2019]
Performance featuring spherical amplification.Festival d’AutomneCité de la Musique, Paris (FR)Ensemble Intercontemporain11/10/2024From the program:Iannotta, Clara (*1983, IT) – They left us grief-trees wailing at the wall (for ensemble) [2020]Iannotta, Clara (*1983, IT) – a stir among the stars, a making way (for large ensemble) [2019-20] French Premiere
Performance featuring spherical amplification.IGNM BernProzess Kultur & Bar, Bern (CH)Solo23/10/2024From the Program:Steen-Andersen, Simon (*1976, DK) – from Beloved Brother: I. Arioso (for ‘backside’ guitar) [2008]Momi, Marco (*1976, IT) – Sans Dire (for guitar and electronics) [2021]Sciarrino, Salvatore (*1947, IT) – L’Addio a Trachis (transcr. for guitar by Francesco Palmieri) [1980/2021]Te
Objective: To report the use of a percutaneous carotid access with vessel closure devices (VCDs) during complex endovascular aortic arch repair. Methods: Seven international high-volume centers conducted a retrospective review of all patients receiving percutaneous carotid access with VCD during endovascular aortic arch procedures to investigate its feasibility and safety. The primary end point wa
Mitochondria play a crucial role in metabolism and energy production by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They also help maintain intracellular calcium levels, facilitate communication between the nucleus and cytoplasm, detoxify reactive oxygen species (ROS), and regulate apoptosis. Reversible acetylation of mitochondrial proteins is a key post-translationa
