The antigen-binding site, the paratope, of an antibody can be seen as being composed of a central core and a more peripheral area situated at its rim. Naturally these regions acquire their diversity using different mechanisms and they also have dissimilar roles, as they contribute differently to the binding interaction. Also, antigens of different size utilize these regions differently; while hapt

Mathematical methods for production scheduling of a complex integrated pulp and paper mill are discussed. The scheduling problem is formulated as an optimal control problem for a multivariable deterministic system. A method of solution for the problem, using optimal control theory, is derived. The method developed is suitable for an on-line process control computer.

The response of the lichen, Cladonia arbuscula (Wallr.) Flot. ssp. mitis (Sandst.) Ruoss to enhanced UV-B (280-315 nm) radiation was investigated with respect to: (a) changes in phenolic content; (b) differential pigment accumulation under visible and UV radiation with increasing distance from thallus apices; and (c) the internal distribution of UV-B radiation within the thallus measured with quar

Objective The Captopril Prevention Project (CAPPP) was designed as a prospective intervention trial comparing the effect of a treatment based on the angiotensin-converting enzyme (ACE) inhibitor captopril with that of a conventional diuretic and/or beta-blocker-based therapy, in 10 985 hypertensive patients. There was no difference in the primary cardiovascular morbidity and mortality endpoint. A

To examine whether altered gene expression of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc is an inherited trait and is associated with muscle insulin resistance or type 2 diabetes, we measured mRNA levels of these genes by a relative quantitative RT-PCR method in muscle biopsies taken before and after an insulin clamp from 12 monozygotic twin pair

Artikeln recenserar Inga Hellbergs bok ”Det fackliga förtroendet. En studie av ombudsmän och experter 1950–1991” (Atlas 1997). Hellbergs studie behandlar professionaliseringstendenser hos ombudsmän och experter inom LO-området. Även Carl-Gösta Hanssons bok "Fackliga karriärer" (Borea 1996) tas upp till diskussion i artikeln, varvid frågan om facklig professionalisering vidgas till TCO- och SACO-sf

Two-phase partitioning bioreactors offer many advantages for the removal of toxic pollutants. In particular, such systems can be loaded with very large quantities of pollutants without risks of microbial inhibition, they are self-regulated and they prevent the risks of hazardous pollutant volatilisation during aerobic treatment. However, their potential has never been tested at low temperatures. P

We present a case of exertional heatstroke, uncommon in the Scandinavian climate zone. Despite early recognition and treatment, our patient underwent a complex clinical course with both renal and liver failure, requiring 4 months of hospital stay and a convalescens of more than a year. In previous reported cases of severe liver failure following exertional heatstroke, liver transplantation has bee

The aim of this thesis was to develop and apply self-registered and observed measures of physical function in people with arthritis in the lower extremity. In Paper I, 181 subjects from the Swedish Knee Arthroplasty Register who were satisfied with their primary knee arthroplasty were studied. 44% of the medical records included reports of pain in the replaced knee at the same time as the patient

The production of combustion products is discussed, especially with respect to the influence of ventilation conditions. Results are presented and compared, from different experimental set-ups. Experimental techniques are presented and discussed.

This study was undertaken to define the role of ultrasound (US) and magnetic resonance (MR) imaging in the diagnosis and preoperative staging of cervico-thoracic lymphangiomas in children. In a retrospective study, 11 patients with surgically and pathologically proved lymphangiomas had MR imaging and 6 of them underwent simultaneous US. US showed superficial hypoechogenic multioccular cystic masse

High spin states in the nucleus Tc-89 have been studied via the fusion evaporation reaction Ni-58(Ca-40,2 alpha p)Tc-89 at 180 MeV beam energy. The NORDBALL gamma-ray spectrometer equipped with auxiliary detectors for light particle selection was used to measure gamma gamma- and particle-gamma gamma coincidences. Some 60 transitions were placed into a level scheme comprising 38 levels reaching up

The NORDBALL detector array has been used in a gamma-ray spectroscopic study of neutron deficient nuclei close to 100Sn. A beam of 270 MeV 58Ni ions was used to bombard a target of Fe-54. Reaction channel separation was achieved with a 4pi charged particle Si-ball together with a 1pi neutron detector wall. Altogether 29 final nuclei were identified and excited states were observed for the first ti

Differentiation from hematopoietic stem cells to mature blood cells of different lineages is a continuous process that requires the coordinated activity of several stage and lineage specific transcription factors. These factors act in a transcriptional hierarchy and also in a combinatorial manner to establish the expression of the genes that comprise a specific differentiation program. The progres