This thesis presents the design and implementation of a web-based simulator, developed to support students in the introductory course in automatic control at LTH. The simulator is meant to serve as a preparatory tool for the laboratories that revolve around two interconnected water tanks, and provides an interactive environment for students to explore system dynamics and PID control prior to atten

Water reuse technologies such as Orbital Systems’ recirculating shower offer significant environmental benefits by reducing hot water consumption. However, these systems rely on depth filters whose performance degrades over time due to clogging. Current maintenance strategies use fixed time intervals or pressure-based thresholds, which do not account for individual usage patterns or actual filter

Machine Protection Systems (MPS) at the European Spallation Source (ESS) aim to protect equipment from damage while minimizing accelerator downtime with respect to safety and availability requirements. Main Control Room operators and MPS experts rely on alarm systems to effectively detect faults and guide intervention actions. Current implementations in the Fast Beam Interlock System (FBIS) are pr

Railway networks are a critical component of modern transportation systems, but their efficiency is often challenged by disturbances that propagate through the network, leading to delays and reduced punctuality. This thesis investigates station-level disturbances and their duration, with the aim of developing a foundation for an online tool that can estimate disturbance durations. Using historical

The possibilities of artificial intelligence (AI) have become evident in recent years, with new applications manifesting the potential. The field of supplier quality management is no exception, as AI shows promise of transforming the field. AI can boost efficiency, increase transparency while also removing human biases, and ensuring one coherent way of working across the organization. Understandin

The All Pairs Shortest Path (APSP) problem is ubiquitous in computer science. The problem consists of finding for any vertex pair, the weighted shortest paths in a network with real-weighted edges. The problem has been studied thoroughly, both for dense graphs, where the number of edges can be quadratic in the number of vertices, and for sparse graphs, where the number of edges is considerably low

The human brain has a built-in capacity to perform selective hearing, allowing us to focus on a single speaker in noisy environments while subconsciously filtering out background chatter and other noise. This ability is colloquially known as the cocktail party effect and is often impaired in individuals with reduced hearing or other neurological conditions. This results in an overall reduced quali

This thesis in collaboration with ESS proposes a workflow for developing, deploying, and integrating machine learning models into the control system. Machine learning offers a promising potential for control systems but often introduces technical debt, with the actual model code representing only a small fraction of the total code base. To address this a data-centric process is proposed for retrie

BackgroundDietary shift is necessary for improving public health, mitigating climate change, and achieving the Sustainable Development Goals. Adaption of climate-friendly diets might prevent chronic diseases and reduce mortality; however, consuming diets with a low climate impact have been suggested to increase risk of some micronutrient deficiencies.ObjectivesThis study aimed to examine whether s

Herpes simplex virus type 1 (HSV-1) delivers its genome into the host nucleus via docking of the viral capsid at the nuclear pore complex (NPC), a process mediated by the capsid vertex-specific complex (CVSC), composed of UL17, UL25, and UL36. While prior in vivo studies have implicated UL25 and UL36 in NPC interactions, their interpretation is complicated by indirect effects from viral traffickin

Hypoplastic left heart syndrome (HLHS) represents a severe spectrum of congenital cardiac malformations, which lead to systemic blood supply being dependent on patency of the arterial duct after birth. Antenatal diagnosis, advances in postnatal care and modifications of surgical palliation strategies have led to improved outcomes with the majority of patients born in the current era being expected

Objective: Emergency department (ED) staff need to rapidly establish accurate diagnosis and management for children with arrhythmias. Limited data are available on the presenting features, epidemiology and management of arrhythmias encountered in the ED. The aim of this study was to characterise the incidence, presenting features, management and outcomes of arrhythmias at a large tertiary children

The provision of safe care is complex and difficult to achieve. Awareness of what happens in real time is one of the ways to develop a safe system within a culture of safety. At Great Ormond Street Hospital, we developed and tested a tool specifically designed for patients and families to report harm, with the aim of raising awareness and opportunities for staff to continually improve and provide

IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing

Ayatollah Ali Khamenei, who has served as Supreme Leader of the Islamic Republic of Iran since 1989, remains unchallenged as the most powerful figure within the country’s theocratic dictatorship. Now 85 years old, renewed attention is being drawn to persistent speculation about his declining health. As Iran prepares for an era without its leading figure, the opaque process of succession once again

As the urgency of environmental challenges grows, companies are increasingly expected to reduce their negative impact and rethink their current practices. In light of this time of change, the aim with the following thesis is to increase the understanding of the conjunction between Sustainable Business Model transformation and Sustainability-Oriented Innovation, and contribute to existing literatur

Background: Developmental exposures to neurotoxic insecticides, as pyrethroids and chlorpyrifos are of growing concern. Objective: To study associations between low prenatal and childhood exposure to pyrethroids and chlorpyrifos and motor skills at age 7. Materials and methods: Data consisted of sub-samples of women and children from the Odense Child Cohort; 883 mother-child pairs with maternal ur

Background: Tattoo inks are mixtures of organic and inorganic color pigments and having a tattoo may be adversely associated with biomarkers of male fecundity. Objective: To examine the association between tattoo exposure and biomarkers of male fecundity. Methods: Participants were young adult Danish males (aged 18–21 years) sampled from the Danish National Birth Cohort. Upon recruitment in 2017–2