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The Microcirculation in Trauma and Sepsis

The microcirculation plays a vital part for fluid-, gas- and solute-exchange, and changes in permeability during trauma or sepsis, that are in part necessary for the natural healing process, may also cause hypovolemia and edema formation, leading to disturbances in microvascular exchange. This thesis discusses changes is microvascular flow, permeability and plasma volume (PV) loss after experiment

Do male ornaments signal immunity in the common yellowthroat?

Male ornaments may advertise genetic benefits to females choosing mates. These benefits may come in the form of genes for resistance to parasites and disease. Thus, females that prefer more ornamented males as mates may receive genes for enhanced immune system function for their offspring. The common yellowthroat (Geothlypis trichas) is the only species to date in which a male plumage ornament (si

Hyperfine characterization and spin coherence lifetime extension in Pr3+:La-2(WO4)(3)

Rare-earth ions in dielectric crystals are interesting candidates for storing quantum states of photons. A limiting factor on the optical density and thus the conversion efficiency is the distortion introduced in the crystal by doping elements of one type into a crystal matrix of another type. Here we investigate the system Pr3+:La-2(WO4)(3), where the similarity of the ionic radii of Pr and La mi

A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2.

The variable regions of allergen-specific IgE, the isotype mediating allergic responses, are poorly defined to date. In this study we define the character of human antibody binding sites recognizing Phl p 2, a major allergen from timothy grass pollen. Independently raised specificities developed by phage display technology tended to have common sequence motifs (idiotypes), such as IGHV4-31 germlin

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

Objectives The aim of this study was to confirm the influence of TNFSF4 polymorphisms on systemic sclerosis (SSc) susceptibility and phenotypic features. Methods A total of 8 European populations of Caucasian ancestry were included, comprising 3014 patients with SSc and 3125 healthy controls. Four genetic variants of TNFSF4 gene promoter (rs1234314, rs844644, rs844648 and rs12039904) were selected

Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays

Antibody microarrays enable extensive protein expression profiling, and provide a valuable complement to DNA microarray-based gene expression profiling. In this study, we used DotScan™ antibody microarrays that contain antibodies against 82 different cell surface antigens, to determine phenotypic protein expression profiles for human B cell sub-populations. We then demonstrated that the B cell pro

The affective profiles, psychological well-being, and harmony: environmental mastery and self-acceptance predict the sense of a harmonious life

Background. An important outcome from the debate on whether wellness equals happiness, is the need of research focusing on how psychological well-being might influence humans' ability to adapt to the changing environment and live in harmony. To get a detailed picture of the influence of positive and negative affect, the current study employed the affective profiles model in which individuals are c

Effects of lifestyle factors on concentrations of salivary cortisol in healthy individuals

Objective . Salivary cortisol is widely used in occupational health research. However, many ordinary daily activities can influence the concentrations of cortisol and the interpretation of field studies. The aim of the present study was to evaluate the effect of lifestyle factors on salivary cortisol in everyday settings. Material and methods . Healthy employees participated in one or more sub-stu

A Coherent Signature of Anthropogenic Nitrogen Deposition to Remote Watersheds of the Northern Hemisphere

Humans have more than doubled the amount of reactive nitrogen (Nr) added to the biosphere, yet most of what is known about its accumulation and ecological effects is derived from studies of heavily populated regions. Nitrogen (N) stable isotope ratios (N-15:N-14) in dated sediments from 25 remote Northern Hemisphere lakes show a coherent signal of an isotopically distinct source of N to ecosystems

Uncovering the corporate brand's core values

Purpose - This paper aims to describe the uncovering of a corporate brand's core values and implications for strategic management of its track record. Design/methodology/approach - The paper examines the specific track records of Volvo, IKEA, IBM, and Scanpump, focusing on core values and how they evolve. Based on multiple sources of evidence, the track records of the case companies emerge as patt

The case of PRO

Icelandic case agreement suggests that nominative case is active in PRO infinitives in much the same way as in finite clauses, thus posing a difficult and a long-standing problem for generative (GB and minimalist) case theory and the PRO Theorem. In this article, I examine the Icelandic facts in detail, illustrating that the unmarked and common nominative morphology in Icelandic PRO infinitives is

Variants in MTNR1B influence fasting glucose levels

To identify previously unknown genetic loci associated with fasting glucose concentrations, we examined the leading association signals in ten genome-wide association scans involving a total of 36,610 individuals of European descent. Variants in the gene encoding melatonin receptor 1B (MTNR1B) were consistently associated with fasting glucose across all ten studies. The strongest signal was observ

Measurement of the cross-section for b-jets produced in association with a Z boson at root s=7 TeV with the ATLAS detector ATLAS Collaboration

A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons,

Measurement of the differential cross-sections of inclusive, prompt and non-prompt J/psi production in proton-proton collisions at root s=7 TeV

The inclusive J/psi production cross-section and fraction of J/psi mesons produced in B-hadron decays are measured in proton proton collisions at root s = 7 TeV with the ATLAS detector at the LHC, as a function of the transverse momentum and rapidity of the J/psi, using 2.3 pb(-1) of integrated luminosity. The cross-section is measured from a minimum P-T of 1 GeV to a maximum of 70 GeV and for rap