Background: The t(6;9)(p23;q34) chromosomal translocation is found in 1% of acute myeloid leukemia and encodes the fusion protein DEK-NUP214 (formerly DEK-CAN) with largely uncharacterized functions. Methods: We expressed DEK-NUP214 in the myeloid cell lines U937 and PL-21 and studied the effects on cellular functions. Results: In this study, we demonstrate that expression of DEK-NUP214 increases

This paper aims to highlight the changing and diversifying nature of academic work related to various forms of knowledge production and diffusion. Focusing on the changing research policy landscape in Sweden, three interrelated questions are investigated: what academics do in terms of commercialisation and public dissemination; how they perform these activities; and why they engage in these activi

Previously found oxidized III-V semiconductor surfaces have been generally structurally disordered and useless for applications. We disclose a family of well-ordered oxidized InAs, InGaAs, InP, and InSb surfaces found by experiments. The found epitaxial oxide-III-V interface is insulating and free of defects related to the harmful Fermi-level pinning, which opens up new possibilities to develop lo

Laser extinction, signal attenuation and multiple scattering are the three main phenomena limiting qualitative and quantitative measurements in planar laser imaging of sprays. In this paper, a method is presented where structured laser illumination planar imaging is used to remove the signal contribution from multiply scattered light. Based on this technique, data from side scattering and transmis

Sepsis is a serious condition characterized by a systemic inflammatory response to an infection. Increased vascular leakage, vasodilation and heart failure cause circulatory disturbances challenging the intensivist. Despite modern medication and high technology supportive care, mortality is high. Key strategies include to find and take care of causative agents at the infection site. Unfortunately,

The recent increase in R&D offshoring has raised fears that knowledge and competitiveness in advanced countries may be at risk of 'hollowing out'. At the same time, economic research has stressed that this process is also likely to allow some reverse technology transfer and foster growth at home. This paper addresses this issue by investigating the extent to which R&D offshoring is associa

The Middle Ordovician (466 Ma) Osmussaar breccia, situated along the northwestern coast of Estonia, is rich in angular chromite grains of extraterrestrial origin (>13 grains kg(-1)) and shocked quartz. The angularity of the chromite grains implies that they have not been transported or reworked to any large extent, connoting that the brecciation is the result of a contemporary impactor, either as

We set up a tasting venue at a local supermarket and invited passerby shoppers to sample two different varieties of jam and tea, and to decide which alternative in each pair they preferred the most. Immediately after the participants had made their choice, we asked them to again sample the chosen alternative, and to verbally explain why they chose the way they did. At this point we secretly switch

Lubricants are used in numerous applications in our society, for instance, as hydraulic fluids. When used in forestry, 60-80% of these hydraulic fluids are released into the environment. This is one of the reasons for the growing interest for developing and utilising hydraulic fluids with good environmental performance. Another driving force in the development of hydraulic fluids is to replace fos

Purpose - The purpose of this paper is to describe a retrospective reflection over unconscious, emergent learning among employees of an organization and to suggest how to capture these moments of experiential learning for future organizational learning. Methodology - Action research in organizations is undertaken in interaction with the employees of the organization studied. The outcome is charact

Popular Abstract in English Clothing plays an important role in our lives. It serves four main functions: adornment, status, modesty and protection. Wearing popular clothing with one’s favourite decorations, contributes to a person reaching his or her mental comfort. Clothing is also a symbol of status, and was particularly so in ancient times. Moreover, it protects the human body from injury fromClothing evaporative resistance is one of the most important inputs for both the modelling and for standards dealing with thermal comfort and heat stress. It might be determined on guarded hotplates, on sweating manikins or even on human subjects. Previous studies have demonstrated that the thermal manikin is the most ideal instrument for testing clothing evaporative resistance. However, the repea

Glypicans are cell-surface heparan sulfate proteoglycans that regulate Wnt, Hedgehog, bone morphogenetic protein, and fibroblast growth factor signaling through their heparan sulfate chains. Recent studies have shown that glypican core proteins also have functional roles in growth factor signaling, but biochemical and structural knowledge regarding the core proteins is limited. Glypican-1 is invol

The well-known Mesolithic cemeteries of Northern Europe have long been viewed as evidence of developing social complexity in those regions in the centuries immediately before the Neolithic transition. These sites also had important symbolic connotations. This study uses new and more detailed analysis of the burial practices in one of these cemeteries to argue that much more is involved than social

Trophic niche divergence is considered to be a major process by which species coexistence is facilitated. When studying niche segregation in lake ecosystems, we tend to view the niche on a one-dimensional pelagic-littoral axis. In reality, however, the niche use may be more complex and individual fidelity to a niche may be variable both between and within populations. In order to study this comple

A novel method for QRST cancellation during atrial fibrillation (AF) is introduced for use in recordings with two or more leads. The method is based on an echo state neural network which estimates the time-varying, nonlinear transfer function between two leads, one lead with atrial activity and another lead without, for the purpose of canceling ventricular activity. The network has different sets

The response of a matrix of 25 lead tungstate (PWO) scintillator detectors, operated at -25 degrees C, to photons in the range 13 MeV-64 MeV has been measured at the tagged-photon facility at MAX-lab, Lund. The tapered PWO crystals, each with a length of 200 mm and a cross-section of 24.4 x 24.4 mm(2) in the front end, read out by 19 mm photomultiplier tubes, were arranged in a 5 x 5 matrix. The r

Applications of microchannel heat sinks for dissipating heat loads have received great attention. Wavy channels are recognized to be an alternative cooling technology to enhance the heat transfer, and are successfully applied in heat exchangers. In this article, three kinds of liquid-cooling double-layer microchannel heat sinks, such as a rectangular straight microchannel heat sink, a parallel-flo