The 125th Anniversary of the Troger's Base Molecule: Synthesis and Applications of Troger's Base Analogues
In 2012 we celebrate the 125th anniversary of the unique molecule Troger's base (TB), first synthesized by Julius Troger in 1887. Being a V-shaped C2-symmetric chiral molecule, it possesses many interesting features. The TB field was reopened in 1985, when Craig S. Wilcox published the first crystallographic study of TB and described the synthesis and potential applications of TB analogues in supr