On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors
Popular Abstract in Swedish Systemisk lupus erythematosus (SLE) är en autoimmun reumatisk systemsjukdom som drabbar flera av kroppens olika organsystem, såsom rörelseapparat, hud och inre organ. Vidare ses en mångfald störningar i kroppens immunsystem. Sjukdomen drabbar oftast kvinnor. Vad som orsakar SLE är ännu så länge ofullständigt klarlagt, men man vet att yttre faktorer (miljöfaktorer) samveSystemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement syste
