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WCMM Fellow | Glia-Immune Interactions Our research The brain has a tight blood-brain barrier limiting the removal of solutes to the vascular compartment, and does not contain any lymphatic vessels. Instead, a peri-vascular bulk flow system, named the glia-lymphatic (glymphatic) facilitates brain-wide clearance. The glymphatic system mediates exchange of solutes and peptides, such as amyloid beta,

https://www.wcmm.lu.se/wallenberg-molecular-medicine-fellow-nervous-system - 2025-10-03

WCMM Fellow | Cell and Molecular Mechanobiology Our research The goal of Laboratory of Cell and Molecular Mechanobiology (LCMM) is to gain a quantitative, molecular-level understanding of how cells and tissues sense, transmit and respond to mechanical information from their environment to regulate critical physiological functions.  Cells in our body exist not only in a rich biochemical environment

https://www.wcmm.lu.se/vinay-swaminathan - 2025-10-03

WCMM Fellow | Vascular Biology Our research Cardiovascular disease, such as heart attack, stroke, and peripheral vascular disease, is the number-one health problem in the world. Despite remarkable progress in diagnosis and prevention, cardiovascular diseases cause disability and death at an astounding rate. The best opportunities to develop and implement new strategies for preventing and treating

https://www.wcmm.lu.se/anja-meissner - 2025-10-03

WCMM Fellow | Diabetes & Brain Function Our research Our purpose is to understand molecular determinants of cognitive impairment associated with metabolic disease, metabolic syndrome component such as including obesity, dyslipidaemia, hypertension, insulin resistance and hyperglycaemia. Our team is interested in understanding regulation of neuron-glia metabolic interactions, how energy metabolism

https://www.wcmm.lu.se/joao-duarte - 2025-10-03

WCMM Fellow | Regenerative Immunology Our researchThere is tremendous variation in how different species respond to injuries. Following an injury, humans are able to heal wounds, but are left with a scar. This limited regenerative ability is also seen following the amputation of a limb, where humans are unable to regenerate following amputation. In contrast, salamanders are able to fully regenerat

https://www.wcmm.lu.se/nicholas-leigh - 2025-10-03

WCMM Fellow | Clinical Memory Research Our research Alzheimer’s disease (AD) is a common neurodegenerative disease, which causes immense suffering for tens of millions of patients and their relatives, and huge financial burdens for societies worldwide. Despite intense research efforts, there is still no cure or disease-modifying treatment for AD, although recent breakthroughs have created hopes th

https://www.wcmm.lu.se/niklas-mattsson-carlgren - 2025-10-03

WCMM Fellow | Lung Bioengineering and Regeneration Our research The Lung Bioengineering and Regeneration (LBR) Lab at Lund University focuses on growing new lung tissue in the lab for transplantation or to use this bioengineered tissue to study how the extracellular environment directs stem cell behavior. We use a multidisciplinary approach using advances in materials science (polymer design and s

https://www.wcmm.lu.se/darcy-wagner - 2025-10-03

WCMM Clinical Researcher | Cardiovascular Research - Translational Studies Our research Type 2 diabetes (T2D) is increasing rapidly and patients suffering from T2D have a greatly increased risk to suffer from cardiovascular events due to accelerated atherosclerosis with more frequent plaque ruptures. Yet, why atherosclerotic plaques tend to rupture more frequently in T2D remains unknown. Our resea

https://www.wcmm.lu.se/andreas-edsfeldt - 2025-10-03

WCMM Clinical Researcher | Medical Imaging Our research Medical imaging has profoundly changed medicine as it allows for non-invasive examination of both morphology and function. For translational science, imaging is a powerful tool, as the same imaging techniques can be used to evaluate treatment response in pre-clinical animal models, early human experiments, and finally in large clinical studie

https://www.wcmm.lu.se/einar-heiberg - 2025-10-03

WCMM Clinical Researcher: Nuclear Medicine Imaging Our research Positron emission tomography (PET) is a nuclear medicine imaging technique that depicts the spatial distribution of metabolic or biochemical activity in the body. It is most often combined with a computed tomography (CT) to obtain anatomic images. PET-CT is the fastest growing imaging modality with increasing use in different clinical

https://www.wcmm.lu.se/elin-tragardh - 2025-10-03

WCMM Clinical Researcher | Translational Neurology Our research Being a neurologist, my vision is to contribute to discovery, development and clinical implementation of novel therapies for neurological disorders. As such, I perform clinical trials and also have a preclinical research group. The overarching goal of our research is to modify disease progression. We are especially interested in peric

https://www.wcmm.lu.se/gesine-paul-visse - 2025-10-03

WCMM Clinical Researcher | Molecular Epidemiology & Cardiology Our research Heart disease remains the leading cause of death globally. Major transitions in the spectrum of heart disease have occurred over time while the end-result, failure of the human heart to maintain sufficient output of blood for the demands of the body, referred to as heart failure, remains a common condition with high mortal

https://www.wcmm.lu.se/gustav-smith - 2025-10-03

WCMM Clinical Researcher | Vessel Wall Biology Our research Pulmonary hypertension (PH), high blood pressure in the lung, is a devastating condition where no curative treatment is available. It can be idiopathic (of unknown cause) or associated with other conditions. In children, PH associated with congenital heart disease is one of the most common types.  Ongoing projects in the group are aimed a

https://www.wcmm.lu.se/karin-tran-lundmark - 2025-10-03

WCMM Clinical Researcher | Hematopoietic & Immune Development Our research Hematopoietic cell transplantation (HCT) is often considered a last treatment resort for a number of serious diseases, including malignancies. Prior to HCT, high doses of chemotherapy are administered to the patients in means to eliminate the underlying malignancy such as leukemia. Also, it aims to create space for donor he

https://www.wcmm.lu.se/kees-jan-pronk - 2025-10-03

WCMM Clinical Researcher | Infection Medicine Our research My research group studies the airway microbiome and respiratory tract infections in lung transplant recipients and patients with the genetic disorder cystic fibrosis (CF). Both groups of patients have an altered airway microbiome due to the underlying disease and frequent antibiotic treatments. Acute and chronic airway infections are commo

https://www.wcmm.lu.se/lisa-pahlman - 2025-10-03

WCMM Clinical Researcher | Cardiovascular Research Our research The core my groups research is to bridge the surprisingly under-explored gap between the “omics” of epidemiology (e.g., genomics, metabolomics, proteomics and target biomarkers) and biological and clinical function. Thus, a major component of my research aims to enhance the understanding of causes to progressing diabetes and cardiovas

https://www.wcmm.lu.se/martin-magnusson - 2025-10-03

WCMM Clinical Researcher | Pediatric Rheumatology Our research Can children get rheumatic joint disease? Is it a life-long disease? Does my child really need all these drugs?! These are the questions we hear every week when meeting families to children with newly diagnosed inflammatory joint disease. To get a chronic disease will have a major impact on your day-to-day life and suddenly you are dif

https://www.wcmm.lu.se/robin-kahn - 2025-10-03

WCMM Clinical Researcher | Translational Lung Transplantation & Cell Therapy Research Our research The Lindstedt group is led by Professor Sandra Lindstedt, a senior consultant in thoracic surgery specializing in heart and lung transplantation, with a long-standing interest in lung transplantation related research, post-transplant complications and lung regeneration. Lung transplantation (LTx) is

https://www.wcmm.lu.se/sandra-lindstedt - 2025-10-03

WCMM Clinical Researcher | Tumor Microenvironment Our research Despite recent advances, there is still a substantial unmet medical need for novel cancer therapeutics. A new class of pharmacological compounds, based on RNA, open up new possibilities to specifically target numerous cancer cell vulnerabilities. Cytosolic delivery of the macromolecular RNA molecules is the biggest hurdle to translate

https://www.wcmm.lu.se/anders-wittrup - 2025-10-03

The WCMM Friday club started in spring 2019 as a monthly scientific meeting for all clinical and preclinical PIs at WCMM Lund. It serves as a platform for presenting ongoing scientific work in each member’s research program. The informal format allows for open discussions, brainstorming and encourages new collaborations. WCMM Friday Club | November 2024 29th November  | Host: Leigh Lab12:00-12:30

https://www.wcmm.lu.se/whats/wcmm-friday-club - 2025-10-03