Plasmodium falciparum is the causative agent of the most severe type of malaria, a life-threatening disease affecting the lives of over three billion people. Factors like widespread resistance against available drugs and absence of an effective vaccine are seriously compounding control of the malaria parasite. Thus, there is an urgent need for the identification and validation of new drug targets.

Individual variation of the female sex pheromone signal in Agrotis segetum was determined by gas chromatographic analysis. The individuals varied extensively, both in absolute and relative amounts of the three major pheromone components; Z5-10:OAc, Z7-12:OAc and Z9-14:OAc. Within individuals there was a strong correspondence between the sex pheromone gland content and the signal actually emitted.

The metallation of tetrapyrroles is believed to proceed via a sitting-atop (SAT) complex, in which some of the pyrrole nitrogen atoms are protonated and the metal ion resides above the ring plane. No crystal structure of such a complex has been presented, but NMR and EXAFS (extended X-ray absorption fine structure) data has been reported for Cu2+ in acetonitrile, which have been interpreted as the

Paroxysmalt förmaksflimmer initieras av extraslag som ofta uppstår i lungvenerna. Kateterablation av impulsledning från lungvenerna kan bota paroxysmalt förmaksflimmer. Även andra impulsursprung kan elimineras genom kateterablation, förutsatt att lokalisationen kartläggs elektroanatomiskt.

Do altered land management practices offer possibilities to sequester carbon in the soil and thereby mitigate increasing atmospheric CO2 as well as improve local soil fertility? This study investigates the impact of fallow periods on soil organic carbon in semiarid subsistence agroecosystems on sandy and poor soils in Kordofan, Sudan. The area is characterized by low-input cultivation of millet an

Introduction: Biokinetic and dosimetry studies in small animals often precede clinical radionuclide therapies. As in human studies, a reliable evaluation of therapeutic efficacy is essential and must be based on accurate dosimetry, which must be based on a realistic dosimetry model. The aim of this study was to evaluate the differences in the results when using a more anatomic realistic mouse phan

In a prospective study, peripheral pulses, claudication, peripheral oedema, and rest pain were evaluated in 314 sequentially presenting diabetic patients with foot ulcers. In the ulcerated limb pedal pulses were found to be present in 44% of the patients, peripheral oedema in 38%, and rest pain in 19%. Twelve per cent had claudication. Presence of pedal pulses was more common in patients whose ulc

High-spin levels in the heaviest stable isotope of chromium were observed following the fusion-evaporation reaction C-12(Ca-48, alpha 2n)Cr-54 at a beam energy of 157 MeV, using the GAMMASPHERE and MICROBALL detector arrays. Numerous yrast and near yrast levels are reported, and previously assigned 7(+) and 9(+) levels are suggested to be 5(+) and 7(+), respectively. The inferred level scheme is c

BchI, belonging to the AAA+-protein family, forms the enzyme magnesium chelatase together with BchD and BchH. This enzyme catalyses the insertion of Mg2+ into protoporphyrin IX upon ATP hydrolysis. Previous studies have indicated that BchI forms ATP-dependent complexes and it is a member of the AAA+-protein family (ATPases associated with various cellular activities) and it was suggested based on

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Light-induced absorbance changes were investigated in vivo in the fungus V. agaricinum (Link) Corda. There was a broad light-induced absorbance decrease in the blue and near UV with a maximum at 384 nm. An action spectrum indicated that the absorbance changes were due to photo-bleaching of a pigment with an absorption spectrum that was similar to the action spectrum. Neither redox reactions nor en

This paper presents results from dynamic calorespirometric measurements on the two mould fungi Penicillium roqueforti and P. camemberti growing on agar. The measurements were made with two isothermal heat conduction calorimeters connected by a tube. In one of the calorimeters, the sample was placed and the other contained a carbon dioxide absorbent. Pressure sensors were connected to both the ampo

Continuous full filling capillary electrochromatography with nanoparticles as pseudostationary phase interfaced with electrospray ionisation mass spectrometric detection was used for reversed phase separations with very high separation efficiency. Several batches of nanoparticles were synthesised and their electrochromatographic performance were evaluated. Different parameters, such as repeatabili

Purpose: The isolated bladder expresses autonomous activity, which may contribute to the generation of lower urinary tract sensation or pathophysiology. We evaluated how the effect of a cholinergic agonist on autonomous activity alters with increasing volume and in the presence of substances known to modulate functional bladder capacity. Materials and Methods: The bladder of 22 adult female C57 bl