Sökresultat

Filtyp

Din sökning på "*" gav 529446 sökträffar

Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

Popular Abstract in Swedish I denna avhandlig undersöks hur mekanisk sträckning påverkar den glatta muskulaturen som omger våra blodkärl. En ökad sträckning av blodkärlen sker till exempel vid högt blodtryck vilket leder till en förändrad struktur av kärlet, så kallad remodellering. Ett annat mekaniskt stimuli utgörs av blodets friktion mot de endotelceller som täcker blodkärlens kontaktyta mot blThe vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. The molecular mechanisms involved are not well defined, but c

Värdering av kvalitet i lokal kollektivtrafik med Stated Preferences-metoden

Popular Abstract in Swedish För att pröva om värdering av kvalitet i kollektivtrafik med Stated Preferences-metoden kan göras i brevenkäter skickades olika enkäter ut till i förväg kontaktade bussresenärer. Studien visar att metoden kan användas i brev och att typen med parvisa val i så fall bör användas. En annan studie visar att erfarenheten av det man värderar har stor betydelse för värderingenTo test whether it was possible to conduct a Stated Preference study by mail, six different types of questionnaires were sent out to previously contacted bus passengers. Several quality comparisons showed that binary choices worked best. Another study showed that the experiences of travellers are of great importance to their evaluations.

The single stage AMS machine at Lund University: Status report

In May 2003 Lund University, Sweden, ordered a new AMS facility from National Electrostatics Corp. (NEC), Wisconsin. The system is the first low energy, open air, single stage AMS system (SSAMS). The machine is equipped with a dual ion source sequential injector, which allows measurements of carbon with the masses 12, 13 and 14. The machine operates at 250 kV with the gas stripper, high energy mag

Development of a dosing strategy for a heavy-duty diesel exhaust cleaning system based on NOx storage and reduction technology by Design of Experiments

A dosing strategy for the transient control of an exhaust after-treatment system using the NOx storage and reduction approach was developed on a heavy-duty diesel engine rig equipped with an I I I diesel engine. The catalysts were oxidation catalysts of 8.41 and NOx storage and reduction catalysts of 16.8 1 total volume. The dosing strategy has been tested in a European Transient Cycle (ETC) resul

Derivative Prices for Models using Levy Processes and Markov Switching

Popular Abstract in Swedish Denna avhandling behandlar matematik, finans och dator simuleringar. I matematiska termer handlar den om tillämpad sannolikhetsteori och från ett finansiellt perspektiv handlar den om derivatprissättning. Avhandlingen är organiserad som följer. De två första kapitlen presenterar derivatprissättning och levy processer. Kapitel 3 beskriver och undersöker en simulerings mThis thesis contributes to mathematics, finance and computer simulations. In terms of mathematics this thesis concerns applied probability and Lévy processes and from the financial point of view the thesis concerns derivative pricing. Within these two areas several simulation techniques are investigated. The thesis is organized as follows. The first two chapters are to be considered as reviews on

Arterial occlusion due to Listeria meningoencephalitis in an immunocompromised boy

Sequential CAT scan studies of the brain were performed in a 7-year-old boy with Listeria monocytogenes serotype 1 meningoencephalitis. The infection occurred while he was receiving maintenance chemotherapy for T-cell non-Hodgkin lymphoma. A lesion in the right hemisphere during the infection resulted in an excessive enlargement of the right ventricle 10 months later, most probably caused by arter

Euroquest: the validity of a new symptom questionnaire

The new questionnaire Euroquest was designed to study effects from exposure to organic solvents, and it covers the most commonly reported symptoms associated with long-term solvent exposure. Its convergence and criterion validity were evaluated by means of comparison with the two well-established generic symptom questionnaires Symptom Checklist (SCL-90) and General Health Questionnaire (GHQ-30). M

Integration of Molecular Biology and Morphology in Effusions with Focus on in situ Detection of Telomerase and its Components

Popular Abstract in Swedish Den viktigaste uppgiften inom den kliniska cytologin är att påvisa cancerceller i olika typer av cellprover. Många olika cancertumörer sprider sig till lungsäcken och bukhålan och ger då ofta upphov till vätska (exsudat) som innehåller cancerceller. Ofta kan cancerdiagnosen ställas på grundval av cellernas utseende men detta är inte alltid möjligt, eftersom cancercellerClinical cytology is a rapid method to detect malignancy in effusions of the serous cavities, but the morphological characteristics of the cells do not always allow diagnosis and a specific marker for malignant cells would improve the diagnostic performance. Telomerase adds telomere repeats to the chromosome ends. It is the most promising universal indicator of malignancy and the project focuses o

Modulation of postendocytic sorting of G-protein coupled receptors

Recycling of the mu opioid receptor to the plasma membrane after endocytosis promotes rapid resensitization of signal transduction, whereas targeting of the delta opioid receptor (DOR) to lysosomes causes proteolytic down-regulation. We identified a protein that binds preferentially to the cytoplasmic tail of the DOR as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor-as

Orthosis as prognostic instrument in lumbar fusion. No predictive value in 50 cases followed prospectively

To evaluate pain relief in a lumbar orthosis as a predictor for good clinical results after solid fusion, all patients scheduled for such a surgical procedure were preoperatively encouraged to use an orthosis, soft or rigid, for 3 weeks. Grade of back pain relief as a percent using the orthosis was assessed by the patients and was registered before surgery. After surgery, at 1-year follow-up, pati

Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation

Multipotent self-renewing hematopoietic stem cells (HSCs) are responsible for reconstitution of all blood cell lineages. Whereas growth stimulatory cytokines have been demonstrated to promote HSC self-renewal, the potential role of negative regulators remains elusive. Receptors for tumor necrosis factor (TNF) and Fas ligand have been implicated as regulators of steady-state hematopoiesis, and if o

Identification of brain tumours in rats using laser-induced fluorescence and haematoporphyrin derivative

Laser-induced fluorescence has been used for the identification of brain tumours in rats, which have been previously given tumour-seeking haematoporphyrin derivative. A pulsed nitrogen laser (λ=337 nm) was used in conjunction with an optical multichannel analyzer. For both inoculated RG-2 and TCVC rat-brain-tumour models, the blue autofluorescence was strongly reduced in the tumour compared with

MR imaging in recurrent pain after back surgery. A comparative study using standard and high doses of gadolinium contrast agents

PURPOSE: To compare the diagnostic results following injection of (a) a high dose (0.3 mmol/kg b.w.) of gadodiamide injection and (b) the standard dose (0.1 mmol/kg b.w.) of Gd-DTPA, in patients with recurrent symptoms after surgery for lumbar disc herniation. MATERIAL AND METHODS: Twenty patients with recurrent or sustained symptoms after surgery for lumbar disc herniations were examined. MR imag

Oligosaccharide mapping of proteoglycan-bound and xyloside-initiated dermatan sulfate from fibroblasts

The copolymeric structure of dermatan sulfate chains synthesized by skin fibroblasts has been examined. Chains initiated onto exogeneous p-nitrophenyl-beta-D-xylopyranoside or attached to protein in a large proteoglycan, PG-L, and two small proteoglycans, PG-S1 and PG-S2, have been compared by using high resolution electrophoresis and gel chromatography of oligosaccharides generated by specific en

The European Frontier : Clashes and Compromises in the Middle Ages

During the Middle Ages the concepts of `them and us' became concrete in the shape of fiercely defended frontiers, some of which were physical, geographic and political, while others were more ideological. This volume, the proceedings of an international symposium held at Lund University in 2000, presents twenty-four papers which examine the archaeological evidence for frontiers across Europe. Divi