Objective: Women with psoriatic arthritis (PsA) may have reduced tumor necrosis factor inhibitor (TNFi) effectiveness compared to men. We examined sex differences in treatment response and retention rates during 24 months of follow-up among patients with PsA initiating their first TNFi. Methods: Data from patients with PsA across 13 European Spondyloarthritis Research Collaboration Network registr

We investigate the spatial characteristics of high-order harmonic radiation generated in argon and observe cross-like patterns in the far field. An analytical model describing harmonics from an astigmatic driving beam reveals that these patterns result from the order and generation position-dependent divergence of harmonics. Even small amounts of driving field astigmatism may result in cross-like

A novel photoemission type of X-ray Beam Position Monitor (XBPM) for the 'white' undulator radiation is proposed. The XBPM employs beamline frontend fixed mask as a source of photocurrent signal. Signal spatial distribution and XBPM response were analyzed for various undulator radiation parameters.

Feedforward control loops are used in numerous applications to correct process variables. While feedforward control loops correct process variables according to the expected behavior of a system at any given setpoint, feedback loops require measurements of the output to correct deviations from the setpoint. At MAX IV, a generic multi-dimensional input and output feedforward controller was implemen

We present a detailed investigation into a source of distortion that affects the classic bootstrapped switch. Our analysis reveals that the transition phase between track mode and hold mode is a critical factor in causing the distortion. To address this issue, we propose a novel technique that effectively mitigates the problem. Our results, based on simulations conducted using a 22-nm FDSOI CMOS p

Recent methods on privacy-preserving image-based localization use a random line parameterization to protect the privacy of query images and database maps. The lifting of points to lines effectively drops one of the two geometric constraints traditionally used with point-to-point correspondences in structure-based localization. This leads to a significant loss of accuracy for the privacy-preserving

Introduction: Analysis of an individual’s immunoglobulin (IG) gene repertoire requires the use of high-quality germline gene reference sets. When sets only contain alleles supported by strong evidence, AIRR sequencing (AIRR-seq) data analysis is more accurate and studies of the evolution of IG genes, their allelic variants and the expressed immune repertoire is therefore facilitated. Methods: The

In this paper, we present a novel algorithmic and hardware co-design approach specifically tailored for efficient 2D convolution implementations, a crucial operation in convolutional neural networks (CNNs). Our method addresses the limitations of existing software-based solutions and hardware-based architectures, delivering significant improvements in asymptotic behavior for generic convolution ca

Beyond-5G wireless communication systems will feature advanced, key technologies such as large intelligent surfaces (LISs) composed of a very large number of antenna elements. The concomitant tremendous data rate requirements, due to the communication between these antennas, necessitate careful algorithm-architecture codesign. This paper presents an application-specific integrated circuit (ASIC) a

Based on the results of an on-going monitoring program of 1612 MHz OH masers in OH/IR stars, we determined a lifetime encompassing late AGB and early post-AGB evolution of at least 4500 years. Fading of the OH masers observed with the Nançay Radio Telescope is detected in several post-AGB OH/IR stars on timescales of decades, while AllWISE/NEOWISE light curves taken almost in parallel show diverse

The anticipated continuation of the last three decades of growth of global demand for high-speed high-coverage mobile data, calls for massive investments in cellular infrastructure, for the ongoing roll out of the fifth generation of mobile systems, but also later for the sixth generation. A key enabler, for the high-speed part, is for the cellular system to move up in frequency and support commun

The main purpose of this brief reflection is to examine the relationship between (a) Muslim communal values of neighborliness, mutual support and responsibility for those living together in a defined, spacial community and b)the built environment and structures of mosques and community gathering spaces, with a focus on how the existence of such a built environment and infrastructure helps to devel

Sport-related concussion (SRC) is a serious injury in youth team sports, including handball. While research on the prevention of SRC has made progress over the past 5 years, prevention strategies are lacking in handball. The aim was to explore and develop strategies focusing on information, rules and training that may prevent concussion in youth handball by incorporating knowledge from experts and

BACKGROUND: Partial nitritation-anammox (PNA) is a biological nitrogen removal process commonly used in wastewater treatment plants for the treatment of warm and nitrogen-rich sludge liquor from anaerobic digestion, often referred to as sidestream wastewater. In these systems, biofilms are frequently used to retain biomass with aerobic ammonia-oxidizing bacteria (AOB) and anammox bacteria, which t

High-fidelity numerical simulations of partial differential equations (PDEs) given a restricted computational budget can significantly limit the number of parameter configurations considered and/or time window evaluated. Multi-fidelity surrogate modelling aims to leverage less accurate, lower-fidelity models that are computationally inexpensive in order to enhance predictive accuracy when high-fid

Uncertainty quantification (UQ) tasks, such as sensitivity analysis and parameter estimation, entail a huge computational complexity when dealing with input-output maps involving the solution of nonlinear differential problems, because of the need to query expensive numerical solvers repeatedly. Projection-based reduced order models (ROMs), such as the Galerkin-reduced basis (RB) method, have been

A data-driven method combined with the formulations of boundary integral equations is developed for the frequency-domain analysis of parametrized acoustic systems, arising from the spatial discretization of the linear Helmholtz equation. The method derives surrogate models for the approximation of frequency response functions at selected field points via the construction of neural networks with ra