Background: Both lifestyle and genetic predisposition determine the development of type 2 diabetes (T2D), and studies have indicated interactions between specific dietary components and individual genetic variants. However, it is unclear whether the importance of overall dietary habits, including T2D-related food intakes, differs depending on genetic predisposition to T2D. We examined interaction

Background: Early initiation of breastfeeding (EIBF) lowers the risk for all-cause mortality in babies, including those with low birth weight. However, rates of neonatal mortality and delayed initiation of breastfeeding remain high in most low- and middle-income countries. This study aimed to assess the trends and factors associated with EIBF in Namibia from 2000 to 2013. Methods: An analysis of E

Many features of the development of reptiles are affected by temperature, but very little is known about how incubation temperature affects gene expression. Here, we provide a detailed case study of gene expression profiles in common wall lizard (Podarcis muralis) embryos developing at stressfully low (15°C) versus benign (24°C) temperature. For maximum comparability between the two temperature re

Background: The unanticipated difficult airway is a potentially life-threatening event during anaesthesia or acute conditions. An unsuccessfully managed upper airway is associated with serious morbidity and mortality. Several bedside screening tests are used in clinical practice to identify those at high risk of difficult airway. Their accuracy and benefit however, remains unclear. Objectives: The

Regression trees are evaluated with respect to mean square error (MSE), mean integrated square error (MISE), and integrated squared error (ISE), as the size of the training sample goes to infinity. The asymptotically MSE- and MISE minimizing (locally adaptive) regression trees are characterized. Under an optimal tree, MSE is O(n^{-2/3}). The estimator is shown to be asymptotically normally distrib

Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot

Several studies have shown that time domain reflectometry (TDR) can be used to measure water content and solute concentration during steady-state experiments with constant soil water content. Few studies have been carried out to identify the relationship between bulk electrical conductivity (σa) and soil solution electrical conductivity (σw) to be used for transient conditions with varying water c

Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein (oxLDL), apoptotic cells and several pathogens like Streptococcus pneumoniae. Immunoglobulin M against PC (IgM anti-PC) has the ability to inhibit uptake of oxLDL by macrophages and increase clearance of apoptotic cells. From our genome-wide association studies (GWASs) in four Europeanancestry cohorts, six single nucleotide p

We experimentally explore the role of collective incentives in sustaining cooperation in finitely repeated public goods games with imperfect monitoring. In our experiment players only observe noisy signals about individual contributions, while total output is perfectly observed. We consider sanctioning mechanisms that allow agents to commit to collective punishment in case total output fall short

Although Singapore, a linguistically and ethnically diverse city–state, uses four official languages, namely Malay, Mandarin, Tamil, and English, which are supposed to enjoy equal status, there appears to be a pecking order to these languages. English seems to be the dominant language when taking into consideration the bilingual education policy, numerous campaigns promoting its use in terms of sp

Rye kernel bread (RKB) evening meals improve glucose tolerance, enhance appetite regulation and increase satiety in healthy volunteers. These beneficial effects on metabolic responses have been shown to be associated with increased gut fermentation. The present study aimed to elucidate if RKB evening meals may cause rapid alterations in microbiota composition that might be linked to metabolic-, im

Pedagogik är en av de klassiska vetenskapliga disciplinerna och har som universitetsämne en hundraårig tradition. I takt med att samhället förändras har även det innehåll som sysselsätter pedagogiken ändrats. Var befinner sig det vetenskapliga ämnet pedagogik i dag? Hur ser den historiska bakgrunden till ämnets framväxt ut? Vilka är de fundament som håller samman pedagogikämnet? Vilka framtida utm

Quantitative imaging, where every pixel of an image represents a physical quantity (e.g. timeor velocity) is being increasingly used in the field of diagnostic radiology and has potential toenhance medical diagnosis. Quantitative methods for Magnetic Resonance Imaging (MRI)enables measurements of velocity and flow using a technique called Phase Contrast MagneticResonance (PC-MR), and different tim

If not accounted for, temperature effects on the water content and electrical conductivity measured with time domain reflectometry (TDR) will introduce significant errors. In this study, an automated TDR system was used to quantify the temperature dependence of the apparent dielectric constant and electrical conductivity in wet soils. Sandy, clayey, and organic soils were used to examine the effec

Co-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in thCo-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in th