The gene fusion technique is widely used in protein engineering and in this thesis it constitutes the basis of both the construction of artificial bifunctional enzymes and the display of two novel peptides. Artificial bifunctional enzymes have been used as model systems in the studies of native multifunctional enzymes and proximity effects within these complexes. Two various constructs are descri

A strategically minded CFO will realize that strategic corporate risk management is about finding the right balance between risk prevention and proactive value generation. Efficient risk and performance management requires adequate assessment of risk and risk exposures on the one hand and performance on the other. Properly designed, a risk measure should provide information on to what extend the f

Background: Autism spectrum disorders (ASD) are a group of severe childhood neurodevelopmental disorders with still unknown etiology. One of the most frequently reported associations is the presence of recurrent de novo or inherited microdeletions and microduplications on chromosome 16p11.2. The analysis of rare variations of 8 candidate genes among the 27 genes located in this region suggested SE

The overall aim of this work was to increase our knowledge of newborn infants and their mothers, gain a better understanding of attachment and the infants' development and identify infants at risk for poorer emotional, social and cognitive development. An interdisciplinary approach was used. Six studies are included in the thesis. Non-nutritive sucking (NNS) and its relation to neurobehavioural st

The ability to understand packaging and how it contributes to the establishment of efficient logistics and the creation of individualised values for consumers is becoming increasingly important. This licentiate thesis stresses the importance of applying a holistic view of packaging in order to be able to understand how to adapt the distribution channel to meet consumer demands. The study focuses o

Popular Abstract in Swedish Polyaminer finns i alla levande celler, såväl i bakterier som i växter, djur och människor, och utgör en mycket viktig beståndsdel i dessa. Utan dessa polyaminer kan inte cellerna växa och dela sig. Polyaminerna putrescin, spermidin och spermin bildas i cellen från aminosyran ornitin. Till sin hjälp för denna bildning har cellerna ett enzym vid namn ornitindekarboxylas The polyamines putrescine, spermidine and spermine have been shown to be involved in cell growth and differentiation, and are considered to be crucial components of the living cell. The synthesis of polyamines in the cell is strictly regulated. The first and rate-limiting step in the biosynthesis of polyamines is catalysed by the enzyme ornithine decarboxylase (ODC). Mammalian ODC has a very fast