Filtyp
The successful planning, design and management of a traffic system is impossible without knowledge of how the traffic environment affects the behaviour of road users and how the behaviour is related to the main qualities of the traffic system (e.g. safety, efficiency). Automated video analysis is a promising tool for traffic behaviour research in that it enables collection of micro-level behaviour
Kulturartikel om dinosaurietrenden inom film och tv med anledning av tv-serien Dinosauriernas tid (Walking with Dinosaurs) och filmen Dinosaurier (Dinosaurs).
OBJECTIVE: We have evaluated a new technique of cardiac de-airing that is aimed at a) minimizing air from entering into the pulmonary veins by opening both pleurae and allowing lungs to collapse and b) flushing out residual air from the lungs by staged cardiac filling and lung ventilation. These air emboli are usually trapped in the pulmonary veins and may lead to ventricular dysfunction, life-thr
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In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in
OBJECTIVE: To investigate the recently defined Positive and Negative Syndrome Scale for Schizophrenia remission criteria in a naturalistic setting of psychotic patients; to identify causal factors that change remission status; and to validate the criteria against global indices of illness, cognitive functions, and social outcome. METHODS: This was a longitudinal naturalistic study of 162 patients,
Patients with rheumatoid arthritis (RA)-related autoantibodies have an increased mortality rate. Different autoantibodies are frequently co-occurring and it is unclear which autoantibodies associate with increased mortality. In addition, association with different causes of death is thus far unexplored. Both questions were addressed in three early RA populations.
The aims were to evaluate the cognitive performance and clinical diagnosis in patients (<75 years) seeking help for subjective memory complaints, to determine the prevalence of certain psychiatric symptoms and to conduct follow-up examinations. At baseline 41% showed normal cognitive performance (subjective memory impairment; SMI), 37% fulfilled criteria for mild cognitive impairment (MCI) and 22%
Thymic expression of insulin has been suggested to play a major role in negative selection of autoreactive T cells and tolerance induction against pancreatic beta cells. Furthermore, the expression of insulin in peripheral antigen-presenting cells (APC) has been clearly demonstrated but whether thymic negative selection and tolerance induction also depends on peripheral influx of self-antigens (Ag
Recent research in the field of on-line handwriting recognition has been focused on statistical systems such as Hidden Markov Models, Neural Networks or a combination of these. There are however merits of employing an approach based on template matching. The first part of this thesis presents a new strategy for parameterization of on-line handwritten character samples. A novel efficient template m
Många studier har visat på svårigheten att hantera komplexa, gränsöverskridande problem i kortsiktig projektform; likväl fortsätter politikens projektifiering. I denna artikel genomförs en empirisk studie av Malmö stads projektverksamheter i syfte att undersöka förändrande och stabiliserande effekter av projekt. Ett vidare syfte är att utveckla den statsvetenskapliga förståelsen av den ökade använ
Mitochondrial dysfunction is an important cause for neonatal liver disease. Disruption of genes encoding oxidative phosphorylation (OXPHOS) components usually causes embryonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondrial disease with liver and kidney involvement, caused by a homozygous BCS1L mutation (232A>G). This
The observations that hormone-sensitive lipase (HSL) is located in close association to insulin granules in beta-cells and that cholesterol ester hydrolase activity is completely blunted in islets of HSL null mice made us hypothesize that the role of HSL in beta-cells is to provide cholesterol for the exocytosis of insulin. To test this hypothesis, wild type (wt) and HSL null islets were depleted
The national Swedish policy on alcohol has been eroded since the country joined the European Union (EU) in 1996, leading to a steep increase in the private import of alcohol. The paper investigates the impact on drinking patterns of the greater availability of alcohol among adolescents. Two cross-sectional data sets, collected in 2003 (n = 2,760) and 2005 (n = 2,031) in schools in southern Sweden,
