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The aggregation of the protein Amyloid-beta (Abeta) into plaques outside the nerve cells has been recognized in patients with Alzheimer’s disease since 1905. But eliminating the plaques has not helped patients so far. Still, Tomas Roos thinks that Abeta matters, but we may need to focus on the aggregates elsewhere. On February 17, he defends his thesis about prion-like proteins in neurodegeneratio

https://www.multipark.lu.se/article/does-alzheimers-disease-start-inside-neurons-phd-interview-tomas-roos - 2025-12-27

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamine nerve cells which are lost in the p

https://www.multipark.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-12-27

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers. The result, published in the journal Science, paves the way for the formation of fully integrated electronic circuits in living organisms. This news was initially publish

https://www.multipark.lu.se/article/electrodes-grown-brain - 2025-12-27

Kajsa Brolin explores how our genes and environment affect the risk of developing Parkinson’s disease. March 27, she defends her Ph.D. project partly based on MultiPark’s biobank sample collection. Here, she tells about the newly discovered genetic risk factor that might be specific to people in the southern part of Sweden. And is coffee really protective? Tell us about your research! “My research

https://www.multipark.lu.se/article/genes-and-environment-pd-phd-interview-kajsa-brolin - 2025-12-27

After a decade of protocol development and preparations, MultiPark researchers have finally launched the clinical trial. Recently, dopamine-producing cells generated from embryonic stem cells were transplanted into the first Parkinson's patient at Skåne University Hospital. During the autumn 2022, the Swedish MPA (Läkemedelsverket) approved the clinical STEM-PD study. Several of MultiParks PIs hav

https://www.multipark.lu.se/article/stem-pd-bench-bedside-story-multipark-researchers-0 - 2025-12-27

Looking for the next step in your career? In need of some scientific inspiration? Or are you just curious about what MultiPark´s senior researchers are doing and their professional journey? Listen to MultiPark’s new podcast series “Meet our scientists”! In a newly launched podcast, young MultiPark researchers interview our research group leaders about their academic journey and main scientific foc

https://www.multipark.lu.se/article/meet-our-scientists-new-podcast-young-multipark-researchers - 2025-12-27

In the early 1950s, no one knew what caused Parkinson's disease. Then, Arvid Carlsson's discovery of dopamine opened the door to world-leading transplantations for Parkinson's patients. Thanks to the pioneering basic research at MultiPark, stemcell-derived neural cells can now be tested in a clinical trial for the first time. In Parkinson's disease, the nerve cells in an area of the brain that con

https://www.multipark.lu.se/article/world-parkinsons-day-transplantations-parkinsons-disease-time-travel - 2025-12-27

Genetics are one of the keys to understanding neurodegenerative disease. That is why MultiPark researchers with expertise in genetics gather across research groups. Genetics of neurodegenerative diseases is a new special interest group (SIG) addressing scientific and technological needs to unravel the genetics behind diseases such as Parkinson’s and Alzheimer’s. Andreas Puschmann tells about how h

https://www.multipark.lu.se/article/genetics-neurodegenerative-diseases-special-interest-group - 2025-12-27

Three researchers at Lund University, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. Two of them are MultiPark research leaders. They do research on chaperone proteins’ function in neurodegenerative diseases and blood tests for rapid screening of drugs in the treat

https://www.multipark.lu.se/article/double-success-multipark-research-groups-prestigious-eu-grant-round - 2025-12-27

Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international pharmaceutical symposium sponsored by MultiPark. Sarah Tabrizi, a high profile Huntington researcher, and some of MultiPark's own researchers will speak. Medications are the physician's primary tool when treating their patients,

https://www.multipark.lu.se/article/superstars-coming-lund-pharmaceutical-symposium-sponsored-multipark - 2025-12-27

Recent studies indicate that acquired brain injuries, such as traumatic brain injury, trigger potentially harmful responses that may lead to neurodegenerative pathology. “Acquired brain injuries and their links to neurodegeneration diseases” is a new special interest group (SIG) collaborating across research groups to elucidate molecular processes that may mediate the relation between acquired bra

https://www.multipark.lu.se/article/acquired-brain-injuries-special-interest-group - 2025-12-27

Thanks to the recent development of diagnostic tools based on blood biomarkers linked to Alzheimer’s, it is possible to predict whether an individual will develop the disease. Therefore, MultiPark researchers gather across groups to investigate hidden opportunities and develop implementable tools also for other brain conditions with similar approaches. “Development and implementation of fluid biom

https://www.multipark.lu.se/article/fluid-biomarkers-special-interest-group - 2025-12-27

Forskare vid Lunds universitet har i samarbete med kollegor i tyska Dresden, tagit fram ett sätt att kombinera benersättningsmedel och läkemedel med syftet att återbilda ben och läka allvarliga frakturer i exempelvis lår eller underben. Studien, som publiceras i den vetenskapliga tidskriften Science Advances, är gjord på råttor men forskarna menar att metoden i olika kombinationer snart blir klini

https://www.medicin.lu.se/artikel/ny-metod-laker-skelettskador-med-konstgjort-ben - 2025-12-27

Framstående insatser inom reumatologi och epidemiologi samt logopedi och audiologi lyfts fram när Medicinska fakulteten utser två nya hedersdoktorer för 2021. Tuhina Neogi och Laurence B. Leonard kommer att promoveras i Lunds domkyrka den 27 maj 2021. Förebild som ledareProfessor Tuhina Neogi är verksam vid Boston University School of Medicine, USA, inom området reumatologi. Hon är en världsledand

https://www.medicin.lu.se/artikel/nya-hedersdoktorer-vid-medicinska-fakulteten-2021 - 2025-12-27

Forskare publicerar nya rön om validerade biomarkörer för individens risk att utveckla Alzheimers sjukdom. Med en modell som kombinerar nivåerna av två specifika proteiner i blodet hos personer med lättare minnessvårigheter kan forskarna förutsäga risken att utveckla alzheimerdemens på individnivå. Forskarna har även utvecklat en onlinetjänst, en app där läkaren skriver in patientens undersöknings

https://www.medicin.lu.se/artikel/biomarkorer-och-app-forutsager-individers-risk-utveckla-alzheimer - 2025-12-27

João Duarte söker kopplingar mellan kognitiv försämring och diabetes. ”Våra fynd kan en dag bidra till utvecklingen av behandling av metabola eller neurologiska sjukdomar”. João Duarte är en av forskarna på Wallenberg centrum för molekylär medicinsk forskning vid Lunds universitet (WCMM LU). Under hösten 2020 presenterar vi varje vecka en forskare verksam vid centrumet. WCMM vid Lunds universitet

https://www.medicin.lu.se/artikel/mot-veckans-wallenbergforskare-joao-duarte - 2025-12-27

Artrosportalen.se är en ny satsning från forskare vid Lunds universitet för att förmedla korrekt och uppdaterad information om ledsjukdomen artros direkt till patienter, anhöriga eller andra intresserade i allmänheten. Artros är en av våra stora folksjukdomar som orsakar smärta, funktionsnedsättning och försämrad livskvalitet hos omkring 10 procent av den vuxna befolkningen. De vanligaste lederna

https://www.medicin.lu.se/artikel/artrosportalen-ny-kalla-till-kunskap-direkt-fran-forskare-vid-lunds-universitet - 2025-12-27

Forskare inom kardiologi vid Lunds universitet har med hjälp av data från hjärtinfarktregistret Swedeheart studerat associationen mellan rörelsemönster och incidensen av hjärtinfarkt under covid-19 pandemin. Resultat i studien visar att social distansering är associerat med minskat insjuknande i hjärtinfarkt. – När aktiviteten runt restauranger, caféer, biografer, nöjes- och shoppingcenter var som

https://www.medicin.lu.se/artikel/hjartinfarkter-kan-forutspas-med-hjalp-av-mobiltelefoner - 2025-12-27

Valet av Nobelpristagare skapar varje höst rubriker världen över, inte minst den som får litteraturpriset. Den som nominerats men inte blivit utvald får ringa uppmärksamhet, om ens någon. – The winner takes it all, the loser’s standing small, säger Nils Hansson, forskare i medicinens historia och etik vid Düsseldorfs universitet. Tillsammans med kollegor i Tyskland och forskare vid Lunds universit

https://www.medicin.lu.se/artikel/lite-ljus-pa-lakare-som-missat-nobelpriset-0 - 2025-12-27

I en unik studie från Lunds universitet har hälsan hos äldre personer med intellektuell funktionsnedsättning och psykisk ohälsa kartlagts. Fokus har varit på affektiv sjukdom och ångestsjukdom. Resultaten visar på flerfaldig sårbarhet hos den studerade gruppen, med ökad risk för samsjuklighet, övermedicinering, fler oplanerade vårdbesök och fler besök inom slutenvården. – Vi har velat undersöka sa

https://www.medicin.lu.se/artikel/vard-uppfyller-inte-behov-hos-aldre-med-intellektuell-funktionsnedsattning-och-psykisk-ohalsa - 2025-12-27