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Mild hyperventilation with preserved exercise capacity in patients with self-reported long-term dyspnea after COVID-19-a prospective cohort study in a primary healthcare setting

BACKGROUND: Post COVID-19 condition remains a complex and challenging issue, with diverse manifestations, despite accumulating research and clinical experience. Dyspnea is one of the most common symptoms reported in post COVID-19 condition. Cardiopulmonary exercise testing (CPET) offers a cohesive assessment of dyspnea and exercise limitations. The Nijmegen questionnaire is a form for assessment o

A dispositional, state-directed epistemology

The paper combines a truthmaker semantics with a dispositional view of beliefs according to which they are dispositions of agents to act as if truthmakers obtain. This has a number of virtues in that it gives us (i) an exact semantics for belief reports; as well as plausible accounts of both (ii) epistemic closure and (iii) contradictory beliefs. In particular, it allows us to analyze knowledge in

Jerome and His Readers : Authority, Community, and the Ideal of Humility

Jerome of Stridon was one of the most important biblical exegetes in early Christianity. Analyzing letters as well as prefaces to biblical commentaries written by Jerome, this article discusses four criteria which he considered to be necessary for orthodox exegesis to take place: 1) education and learning; 2) studying the Scriptures as part of an ascetic lifestyle; 3) divine help; and 4) learning

Allergen-specific human IgE isolated through an allergen-agnostic pipeline—understanding immune response and allergen recognition

Allergy, characterised by antibody responses of the IgE isotype, is a major health concern. The set of monoclonal human IgE used for studying the molecular mechanisms of allergies is limited. Single-cell sequencing offers opportunities to establish novel antibodies for researching, diagnosis, and treatment of allergies. We describe and exploit a pipeline for generating recombinant IgE directly fro

How Greenland became visible on screen – and why who films it matters

In recent years, Kalaallit Nunaat, as Greenland is known in Kalaallisut (Greenlandic), has come under ever intensifying scrutiny — featuring in debates about geopolitics, climate change and natural resources. As US interest in the island continues, the EU is now stepping into the fray, with Ursula von der Leyen, the president of the European Commission, poised to visit Greenland and the wider Arct

A skin colonizer disrupts inflammatory and humoral immune defenses in hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with a polybacterial dysbiosis devoid of a known pathogen. Here, we report that HS patients mount IgA and IgG responses against skin colonizers, notably Porphyromonas uenonis (Pu), a rare species selectively enriched in severe disease. In these patients, Pu foci are detected in the epidermis, surrounded by IgA deposits

In Focus introduction : 'Runaway Scandinavia'

This introduction to the In Focus section ‘Runaway Scandinavia’ provides background on the phenomenon of runaway and mobile screen production and presents the four short articles that follow. As the first joint effort to address this topic, the In Focus outlines, from a range of perspectives, how the region has become increasingly shaped by global production mobility, incentive-driven competition

Longitudinal Speech Outcomes in Foreign-Born and Native-Born Children in Sweden with Cleft Palate, and Influence of Palatal Surgery Timing

Objective To compare longitudinal speech outcomes at ages 5 and 10 years in foreign-born and Swedish-born children with cleft palate with or without cleft lip (CP ± L), and assess impact of cleft type, additional diagnosed conditions, sex, and age at completed primary palatal surgery.DesignLongitudinal, registry-based cohort study.SettingRegional public care university hospitals in Sweden.Particip

Samernas försvinnande och återkomst? : en studie om framställning av samer i svenska historieläroböcker i gymnasiet under 1970–2025

Denna studie undersöker hur samer har framställts i svenska historieläroböcker för gymnasiet under perioden 1970–2025. Syftet är att analysera hur språkbruk, innehåll och perspektiv har förändrats över tid samt att förstå dessa förändringar i relation till skiftande samhälleliga värderingar och politisk kultur. Studien bygger på ett omfattande källmaterial bestående av 52 läroböcker och kombinerarThis study examines how the Sámi have been represented in Swedish upper secondary school history textbooks between 1970 and 2025. The aim is to analyse changes in language, content, and perspectives over time, and to understand these shifts in relation to broader societal values and political culture. The study is based on an extensive body of source material consisting of 52 textbooks and combine

Evaluation of Thermal Sensor Calibrations Below 1 K For a Horizontal Dilution Refrigerator in a Cryomagnet

Accurate thermometry is essential for experiments in cryogenic environments, particularly those using dilution refrigeration to reach milli-Kelvin temperatures. In this thesis, the calibration range of a Cernox CX1050 sensor was extended below its nominal lower limit of 1.4 K. In addition, the response of RuOx sensors at different positions within the dilution refrigerator was examined to assess t

Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster

A particularly well-studied evolutionary model is the vinegar fly Drosophila melanogaster, a cosmopolitan insect of ancestral southern-central African origin. Recent work suggests that it expanded out of Africa ∼9,000 years ago, and spread from the Middle East into Europe ∼1,800 years ago. During its global expansion, this human commensal adapted to novel climate zones and habitats. Despite much w

Body mass index and subsequent fracture risk: a meta-analysis to update FRAX

The aim of this international meta-analysis was to quantify the predictive value of BMI for incident fracture and relationship of this risk with age, sex, follow-up time, and BMD. A total of 1667922 men and women from 32 countries (63 cohorts), followed for a total of 16.0 million person-years were studied. 293325 had FN BMD measured (2.2 million person-years follow-up). An extended Poisson model

Assessing Eligibility for Anti‐Amyloid Treatment Among Primary Care Patients with Cognitive Symptoms

BackgroundPrimary care is key to early identification and referral of patients with Alzheimer’s disease (AD). Assessing eligibility for new anti-amyloid treatment may guide appropriate referrals and prevent overburdening specialized care. In this study we determined eligibility for anti-amyloid treatment in patients undergoing cognitive evaluation in primary care.MethodPatients were selected from