Colorectal cancer risk in association with colorectal cancer as a second malignancy in relatives : a nationwide cohort study
BACKGROUND: Increasing number of individuals will have first-degree relatives (FDRs) diagnosed with colorectal cancer (CRC), as a second primary malignancy (CRCa-2) after a non-CRC cancer. We aimed to estimate whether and to what extent a family history of CRCa-2 is associated with an increased CRC risk.METHODS: In this Swedish nationwide cohort study, rate ratio (RR) and cumulative incidence of C