Den här uppsatsen handlar om stokastiska optimerings metoder. Inom områdena Artificiell intelligens och Maskininlärning är det vanligt att man vill skatta parametrar i en statistisk modell för att kunna göra prediktioner. Man använder sig då av en kostnadsfunktion som bestraffar prediktioner som ligger långt ifrån det riktiga värdet och minimerar denna med avseende på de statistiska parametrarna. This thesis is concerned with stochastic optimization methods. The pioneering work in the field is the article “A stochastic approximation algorithm” by Robbins and Monro [1], in which they proposed the stochastic gradient descent; a stochastic version of the classical gradient descent algorithm. Since then, many improvements and extensions of the theory have been published, as well as new version

Background: Hospital-acquired hyponatremia remains a feared event in patients receiving hypotonic fluid therapy. Our objectives were to assess post-operative plasma-sodium concentration and to provide a physiological explanation for plasma-sodium levels over time in children with acute appendicitis. Methods: Thirteen normonatremic (plasma-sodium ≥135 mmol/L) children (8 males), median age 12.3 (IQ

Researchers are increasingly recognizing that social movements are crucial for realizing deliberative democratic values. However, this raises two important questions: (1) what actions should count as deliberation and (2) whether we should demand more from activists than merely provoking or encouraging deliberation in a society. Building on current research on activists’ actual engagement with deli

We report on a study of the α-decay fine structure and the associated Eα-Eγ correlations in the decays of Os171,172 and Ir171,172,174. In total, 13 new α-decay energy lines have been resolved, and three new γ-ray transitions have been observed following the new decay branches to Re168 and W167. The weak α-decay branch from the bandhead of the νi13/2 band in Os171 observed in this work highlights a

Purpose: To present age- and sex-specific cumulative annual incidences of primary traumatic lateral patellar dislocation (LPD) and to detail patient characteristics and concomitant chondral injuries including osteochondral fractures, as visualized on magnetic resonance imaging (MRI), in a large consecutive cohort of knee-injured individuals. Methods: Data on primary traumatic lateral patellar disl

Drawing theoretic inspiration from the spatial turn within humanities, this article attempts to develop methods for studying placemaking in news media. This is done by a case study of the newspaper Þjóðviljinn, published in Ísafjörður, Iceland, in the late nineteenth century. The concept ‘banal placemaking’ is suggested for the kinds of spatial conceptions that occur in the paper without the expli

With this special issue and as part of the ELJ's endeavour to foster collaborative research projects on European integration, two of its board members, Jacob Öberg and Valsamis Mitsilegas, threw down a challenge to fellow expertsin European criminal law: to reflect on the normative foundations of European criminal law. This challenge first tookshape with an online symposium organised by Jacob with

Objective: Primary stenting of the superficial femoral artery (SFA) in intermittent claudication (IC) has been shown to increase health related quality of life (HRQoL) after 12 and 24 months. An extended follow up of HRQoL 36 and 60 months after randomisation is presented. Methods: A multicentre randomised controlled trial was conducted at seven vascular clinics in Sweden between 2010 and 2020. On

Acoustic separation of suspension cells can be achieved by altering the properties of the cell medium. Cells of different types can then migrate in opposing directions in the sound field due to differences in their relative density and compressibility with respect to the surrounding fluid. For near-zero acoustic contrast the acoustic radiation force on cells becomes negligible, and it is the prima

Placental dysfunction may increase the offspring’s later-life disease risk. The objective of this systematic review was to describe associations between pathological placental changes and neuropsychological outcomes in children after the neonatal period. The inclusion criteria were human studies; original research; direct placental variables; neuropsychological outcomes; and analysis between their

BACKGROUND: Hereditary angioedema (HAE) is caused by low levels of or defects in C1 inhibitor. Although disease activity may be modified by prophylaxis, emergency treatment, treatment for comorbidities, and oral contraceptives, the extent of their use is unclear. OBJECTIVE: To investigate trends in the use of disease-specific and interfering drugs in patients with HAE compared with the general pop

Background and purpose Hip fractures should be treated based on the best available evidence and cost-effectively to optimize the outcome for this large group of frail patients. This study examined nationwide variation in surgical methods used for hip fractures. Methods In this cohort study 46,243 patients ≥65 years with a trochanteric hip fracture (THF) or a femoral neck fracture (FNF) registered

Oat (Avena sativa) is susceptible to Fusarium head blight (FHB). The quality of oat grain is threatened by the accumulation of mycotoxins, particularly the trichothecene deoxynivalenol (DON), which also acts as a virulence factor for the main pathogen Fusarium graminearum. The plant can defend itself, e.g., by DON detoxification by UGT-glycosyltransferases (UTGs) and accumulation of PR-proteins, e

With the advent of nationwide mammography screening programmes, a number of natural history models of breast cancers have been developed and used to assess the effects of screening. The first half of this article provides an overview of a class of these models and describes how they can be used to study latent processes of tumour progression from observational data. The second half of the article

Antimony (Sb) is a toxic metalloid, which has been increasingly used in the brake lining of vehicles, and increased concentrations have been found in soils near abundant traffic. However, since very few investigations of Sb accumulation in urban vegetation have been undertaken there exists a knowledge gap. We studied the concentrations of Sb in leaves and needles of trees in the Gothenburg City ar

This article contributes guidance on how to approach the development of a course curriculum in general and presents a specific example from medical research education. The purpose of this study is to discuss a model for translating needs assessments of targeted learners into a course curriculum. The model employs established methods for data collection, such as different interview approaches and s

Purpose: Recommender systems (RS) are designed to communicate with users and drive consumers' engagement with the platform. However, little is known about the strength of this relationship and how RS can create stronger consumer engagement (CE) with the platform brand. Addressing this gap, this paper examines the role of RS in converting consumers' short-term engagement with the RS to their longer

Purpose: Corporate brands increasingly use influential, high reach human brands (e.g. influencers, celebrities), who have strong parasocial relationships with their followers and audiences, to promote their offerings. However, despite emerging understanding of the benefits arising from human brand-based campaigns, knowledge about their potentially negative effects on the corporate brand remains li