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Aim: To summarise key epidemiological and therapeutic research on osteoarthritis (OA) published between April 2024 and March 2025. Methods: A narrative review was conducted using the MEDLINE database, focusing on English-language studies involving human participants published between April 1, 2024 and March 31, 2025. Eligible studies included observational longitudinal studies, systematic reviews,
Integrated pest management (IPM) is an important tool for sustainable crop production. IPM includes a diversity of methods, e.g., the use of biological control agents (BCAs) for disease control or growth promotion. While there is an increasing interest in the use of BCAs, less is known about their environmental costs and benefits on wild species, such as wild crop relatives. For example, a BCA may
Femoral neck fractures (FNFs) are associated with loss of function in all ages and excess mortality. The societal costs are high. Treatment needs to be tailored based on fracture type, functional demand, and physiological age of the patient. Internal fixation is often preferred for undisplaced FNFs and for displaced FNFs in young patients. Anatomical reduction is essential, but slight valgus is ac
When developing a research roadmap for human behaviour in fires, it is necessary to identify areas that require additional research. A general overview – from a multidisciplinary perspective – of gaps in human behaviour in fires research across multiple contexts is missing. The goal of this paper was to perform a scoping review to identify research gaps and themes in all aspects of human behaviour
This study investigates how the seven core resilience principles are integrated into assessments of forest system resilience to natural or human-induced disturbances across engineering, ecological, and social-ecological resilience concepts. Following PRISMA guidelines, a literature search in the Web of Science database using the keywords “resilience”, “forest” and “ecosystem services” yielded 1828
Endophytic fungi, which reside within plants without causing disease, are recognized for their ability to produce bioactive metabolites with antibacterial, antifungal, and antioxidant properties, as well as their role in enhancing plant defense mechanisms. Due to these valuable traits, endophytic fungi have attracted significant attention in biotechnology and microbiology. The four endophytic
Background: Perioperative stress or discomfort in shoulder arthroplasty (SA) patients can be reduced using more individually tailored patient education and expectation management. Most published studies assess pain and function for the first time at 6 weeks or 3 months. Consequently, there is no thorough understanding of day-to-day recovery trajectories within the first postoperative weeks, hinder
This study evaluated the psychometric properties of the Swedish version of the Behavior Rating Inventory of Executive Function – Second Edition (BRIEF2) across self-, parent-, and teacher-report forms in a gender- and age-balanced community sample of Swedish youth. We examined factor structure, internal consistency, inter-rater reliability, measurement invariance, and age- and gender-related diffe
Objectives: Breast-fed (BF) have lower risk of infections during infancy compared to those formula-fed (FF). A higher content of alpha-lactalbumin (α-lac) in breast milk, which may promote a more favorable gut microbiota, could be one reason. In this study, we evaluated whether increased concentration of α-lac in low-protein infant formula affects the immune response and the incidence of infection
BACKGROUND: As the global population ages, the demand for palliative care is expected to increase. However, studies show that older patients often receive inadequate palliative care, partly due to healthcare professionals lacking sufficient training and tools to identify and address palliative care needs effectively. This study aims to explore healthcare professionals' experiences regarding facili
Background: Viral infections, including COVID-19, are associated with an increased risk for type 1 diabetes (T1D), but potential underlying mechanisms remain unexplored. We evaluated whether COVID-19 or influenza A infection is characterized by differential DNA methylation at immune and T1D susceptibility genes in young children at risk for T1D. Methods: Epigenome-wide association analysis using t
Trust is a prerequisite for successful learning.From previous work we know that teachers use multiplestrategies to build trust with students – for example todemonstrate knowledge, skill and competence, or showinginterpersonal care and concern. We also know from studentsthat they trust teachers who ask, listen, and respond. But sincewe conducted those studies, Generative Artificial Intelligence(Gen
Background and study aims Surgical resection is standard treatment of T2 rectal cancer due to risk of concomitant lymph node metastases (LNM). Local resection could potentially be an alternative to surgical treatment in a subgroup of patients with low risk of LNM. The aim of this study was to identify clinical and histopathological risk factors of LNM in T2 rectal cancer. Patients and methods This
In this work, we investigate the cryogenic performance of hafnia-based ferroelectric capacitors with and without an aluminum oxide (ALO) interlayer, comparing conventional metal-ferroelectric-metal (MFM) structures to metal-ferroelectric-insulator-metal (MFIM) counterparts. Devices employing Hf0.5Zr0.5O2 as the ferroelectric layer were characterized from 300 K down to 10 K, targeting temperature r
INTRODUCTION: The gold standard for monitoring long-term glucose levels in patients with diabetes mellitus is glycated hemoglobin (HbA1c). In conditions where the erythrocyte half-life is decreased, for example, in long-term kidney diseases and hemoglobinopathies, HbA1C may underestimate the long-term glucose exposure. Therefore, in these patient groups, other methods to monitor long-term glucose
INTRODUCTIONThis study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access.METHODSUsing nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016. The analysis guided by the Andersen healthcare utilization framework, considered predisposing, enabling, and need-
One of the major causes of dwell time delays is the behaviour of passengers during the alighting and boarding processes, such as an uneven spread of boarding passengers and queues formed in front of the doors. Therefore, changing the behaviour of passengers so that it does not negatively affect the time needed for alighting and boarding is one of the ways to reduce the risk of dwell time delays. P
UNLABELLED: Systemic targeted therapy in prostate cancer is primarily focused on ablating androgen signaling. Androgen deprivation therapy and second-generation androgen receptor (AR)-targeted therapy selectively favor the development of treatment-resistant subtypes of metastatic castration-resistant prostate cancer (mCRPC), defined by AR and neuroendocrine (NE) markers. Molecular drivers of doubl
