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Evidence of arterial pulse pressure variations caused by cardio-pulmonary interactions, and their connection to volume status via the Frank–Starling relationship, are well documented in the literature. Computation of pulse pressure variations from arterial pressure measurements is complicated by the fact that systolic and diastolic peaks are not evenly spaced in time. A robust, structurally uncomp
Parkinson's Disease (PD) is a complex and heterogeneous neurodegenerative disease characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta and pathological intracellular accumulation of alpha-synuclein (α-syn). In the vast majority of PD patients, the disease has a complex etiology, defined by multiple genetic and environmental risk factors. Common genetic
Disasters and subsequent recovery efforts often reinforce social inequality and marginalization, hampering sustainable development paths. This paper presents an analysis of inequality and marginalization effects of post-disaster reconstruction from a risk governance perspective. Using a mixed-methods approach, we examine the Fischerdorf and Natternberg districts of the German city of Deggendorf, s
The aim of this study was to identify molecules that trigger complement activation in rheumatic joints. C4d, the final cleavage product of C4 activation, is found in the diseased joint and can bind covalently to complement-activating molecules. By using a highly specific Ab against a cleavage neoepitope in C4d, several molecules that were specifically bound to C4d were identified from pooled synov
The dominating form of analysis in the transport sector is cost–benefit analysis (CBA). This study investigates the purpose and use of an alternative analysis intended to complement CBA in the Swedish high-speed rail project. According to CBA calculations, the project is heavily unprofitable. While some politicians called for project termination, the project leadership launched an alternative bene
Evaporation of sulfuric acid from particles can be important in the atmospheres of Earth and Venus. However, the equilibrium constant for the dissociation of H2SO4 to bisulfate ions, which is the one of the fundamental parameters controlling the evaporation of sulfur particles, is not well constrained. In this study we explore the volatility of sulfate particles at very low relative humidity. We m
Type 2 diabetes is characterized by insulin resistance, which arises from malfunctions in the intracellular insulin signaling network. Knowledge of the insulin signaling network is fragmented, and because of the complexity of this network, little consensus has emerged for the structure and importance of the different branches of the network. To help overcome this complexity, systems biology mathem
Radio-based localization has the potential to provide centimeter-level position information. In this paper we apply joint probabilistic data association to multipath-assisted simultaneous localization and mapping (SLAM) for this purpose. In multipath-assisted localization, position-related information in multipath components (MPCs) is exploited to increase the accuracy and robustness of indoor tra
More than 95% of testicular cancer are cured but they are at increased long-term risk of cardiovascular disease. The risk of cardiovascular disease and treatment intensity was reported, but it is unknown whether this effect of cancer therapy is direct or indirect, mediated through androgen deficiency. Our aim was, therefore, to evaluate whether testicular cancer patients have increased the prevale
The aim of this study was to measure the impact of genetic data in improving the prediction of type 2 diabetes (T2D) in the Malmö Diet and Cancer Study cohort. The current study was performed in 3,426 Swedish individuals and utilizes of a set of genetic and environmental risk data. We first validated our environmental risk model by comparing it to both the Finnish Diabetes Risk Score and the T2D r
In this chapter, New Public Management (NPM) reforms are discussed, with focus on the Swedish public sector. The purpose is to question assumptions concerning the emergence of NPM within a Swedish context. A historical review reveals that reforms within the Swedish public sector express a heavy influence from the private sector; the idea of letting business and commercial logics guide the rational
Sweden is generally regarded as a country with little corruption, equal rights for men and women and a strong emphasis on democratic values. Still, the appointment of political representatives to the boards of municipal corporations occurs without consideration of these values. One step towards increasing our knowledge about the governance of municipal corporations in Sweden is to look at how curr
Forskningsrapporten undersöker i vilken omfattning barn och unga i behov av särskilt stöd inkluderas i kulturskolors verksamhet, enligt kulturskoleledarna. Resultaten, som bygger på kvantitativ data ur en landsomfattande enkätundersökning med kulturskoleledare, avslöjar att det finns sex stycken kulturskolor som inte inkluderar barn och unga i behov av särskilt stöd.
The academic field in Sweden is in a state of transformation. Demands for change are facing universities and colleges. Drawing on empirical illustrations from the public debate in Sweden and from strategic plans of Lund University, analysis shows the prevalence of two dominant logics in the field - collegiality and managerialism. Leadership becomes a matter of handling these logics and making sens
The development of the Swedish welfare state is often characterized by several comprehensive social reforms and organizational changes. In previous research, as in the previous chapters of this book, scholars often tend to direct their interest towards these reforms. Often left out are the tacit administrative technological infrastructures that enabled these. The Swedish social security number, th
The article explores the degree to which memory studies has become established as an academic field. Although we acknowledge that there are drawbacks to formal institutionalization, we contend that it is useful to think strategically about the future of memory studies. We argue that three key developments must take place in order for a field to become institutionalized. First, individual scholars
Our chapter illustrates how citizens can enact varying styles and degrees of political engagement through social media. It also investigates if citizens engage with political content in ways unhindered by national boundaries. We distinguish between three primary types of content styles (factual, partisan and moral) and four degrees of engagement (making, commenting, diffusing and listening). Moreo
